(Q36994561)

17 August 2017

1 reference

title

Metalloproteases and gamma-secretase: new membrane partners regulating p75 neurotrophin receptor signaling? (English)

1 reference

17 August 2017

Francisca C Bronfman

1

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17 August 2017

language of work or name

English

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publication date

1 November 2007

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Journal of Neurochemistry

17 August 2017

published in

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17 August 2017

volume

103 Suppl 1

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17 August 2017

page(s)

91-100

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ADAMs family members as amyloid precursor protein alpha-secretases

17 August 2017

cites work

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p75NTR is positively promiscuous: novel partners and new insights

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ADAMs: key components in EGFR signalling and development

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Multi-tasking by the p75 neurotrophin receptor: sortilin things out?

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Endosomal transport of neurotrophins: roles in signaling and neurodegenerative diseases

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Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations

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A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

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Rab5 and Rab7 control endocytic sorting along the axonal retrograde transport pathway

21 January 2018

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RAC1 inhibition targets amyloid precursor protein processing by gamma-secretase and decreases Abeta production in vitro and in vivo.

21 January 2018

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Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding.

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MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth

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A RIP tide in neuronal signal transduction

21 January 2018

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Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

21 January 2018

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The cytoplasmic and transmembrane domains of the p75 and Trk A receptors regulate high affinity binding to nerve growth factor.

21 January 2018

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Ectodomain shedding of TGF-alpha and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades

21 January 2018

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Characterization of growth factor-induced serine phosphorylation of tumor necrosis factor-alpha converting enzyme and of an alternatively translated polypeptide

21 January 2018

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Nuclear translocation of the p75 neurotrophin receptor cytoplasmic domain in response to neurotrophin binding

21 January 2018

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Association of the atypical protein kinase C-interacting protein p62/ZIP with nerve growth factor receptor TrkA regulates receptor trafficking and Erk5 signaling

21 January 2018

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Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling

21 January 2018

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TRAF6-mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor

21 January 2018

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p75 neurotrophin receptor signaling regulates growth cone filopodial dynamics through modulating RhoA activity.

21 January 2018

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Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury

21 January 2018

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Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes

21 January 2018

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Dissecting the diverse actions of pro- and mature neurotrophins

21 January 2018

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The localization, trafficking and retrograde transport of BDNF bound to p75NTR in sympathetic neurons

21 January 2018

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Modulation of cellular cholesterol transport and homeostasis by Rab11.

21 January 2018

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Trk receptors: roles in neuronal signal transduction

21 January 2018

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Nerve growth factor signaling in caveolae-like domains at the plasma membrane

21 January 2018

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Shedding light on ADAM metalloproteinases

21 January 2018

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Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Metalloprotease-disintegrin (ADAM) genes are widely and differentially expressed in the adult CNS

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Nectin-1alpha, an immunoglobulin-like receptor involved in the formation of synapses, is a substrate for presenilin/gamma-secretase-like cleavage

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-subunit regulates cell adhesion and migration

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

ERK1/2 is an endogenous negative regulator of the gamma-secretase activity

21 January 2018

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Gamma-secretase: proteasome of the membrane?

21 January 2018

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Subcellular topography of neuronal Abeta peptide in APPxPS1 transgenic mice

21 January 2018

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Amyloid excess in Alzheimer's disease: what is cholesterol to be blamed for?

21 January 2018

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Regulation of cell survival by secreted proneurotrophins

21 January 2018

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Neurotrophin receptor interacting factor (NRIF) is an essential mediator of apoptotic signaling by the p75 neurotrophin receptor

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

The yin and yang of neurotrophin action

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Rho GTPases in neuronal morphogenesis

21 January 2018

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A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Roles for NF-kappaB in nerve cell survival, plasticity, and disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Sortilin/neurotensin receptor-3: a new tool to investigate neurotensin signaling and cellular trafficking?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

The Nogo-66 receptor: focusing myelin inhibition of axon regeneration

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Not just a sink: endosomes in control of signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Neurotrophin signalling pathways regulating neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

A novel p75 neurotrophin receptor-related protein, NRH2, regulates nerve growth factor binding to the TrkA receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Activation of beta2-adrenergic receptor stimulates gamma-secretase activity and accelerates amyloid plaque formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Sortilin, SorCS1b, and SorLA Vps10p sorting receptors, are novel gamma-secretase substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

A pro-apoptotic fragment of the p75 neurotrophin receptor is expressed in p75NTRExonIV null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Pro-NGF from Alzheimer's disease and normal human brain displays distinctive abilities to induce processing and nuclear translocation of intracellular domain of p75NTR and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Tumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Neurotrophin signaling through the p75 neurotrophin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Antagonistic effects of TrkB and p75(NTR) on NMDA receptor currents in post-synaptic densities transplanted into Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Differences in the surface binding and endocytosis of neurotrophins by p75NTR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Complete ablation of the neurotrophin receptor p75NTR causes defects both in the nervous and the vascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Syndecan 3 intramembrane proteolysis is presenilin/gamma-secretase-dependent and modulates cytosolic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

The ADAMs family of metalloproteases: multidomain proteins with multiple functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Neurotrophin-induced melanoma cell migration is mediated through the actin-bundling protein fascin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

The p75 neurotrophin receptor interacts with multiple MAGE proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Spatial segregation of gamma-secretase and substrates in distinct membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Zinc metalloproteinase-mediated cleavage of the human Nogo-66 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Evidence for a critical role of the tumor necrosis factor alpha convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

ADAMs: modulators of cell–cell and cell–matrix interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Activation of p75NTR by proBDNF facilitates hippocampal long-term depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Mechanisms of neurotrophin receptor vesicular transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

The p75 neurotrophin receptor negatively modulates dendrite complexity and spine density in hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Cleavage of p75 neurotrophin receptor by alpha-secretase and gamma-secretase requires specific receptor domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Cessation of rapid late endosomal tubulovesicular trafficking in Niemann-Pick type C1 disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Presenilin/gamma-secretase activity regulates protein clearance from the endocytic recycling compartment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

Functions and mechanisms of retrograde neurotrophin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

C-terminal Fragment of Presenilin Is the Molecular Target of a Dipeptidic γ-Secretase-specific Inhibitor DAPT (N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycinet-Butyl Ester)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04781.X

10.1111/J.1471-4159.2007.04781.X

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference