(Q37003852)

English

N-tert-butyl hydroxylamine, a mitochondrial antioxidant, protects human retinal pigment epithelial cells from iron overload: relevance to macular degeneration.

scientific article published on 26 July 2007

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scholarly article

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2 January 2020

N-tert-butyl hydroxylamine, a mitochondrial antioxidant, protects human retinal pigment epithelial cells from iron overload: relevance to macular degeneration (English)

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2 January 2020

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David W. Killilea

2

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2 January 2020

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object named as

Bruce N Ames

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2 January 2020

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Ludmila A Voloboueva

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2 January 2020

Hani Atamna

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2 January 2020

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26 July 2007

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2 January 2020

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2 January 2020

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2 January 2020

4077-4086

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2 January 2020

Iron uptake and metabolism in the new millennium.

1 reference

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29 September 2017

Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome

1 reference

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29 September 2017

Small-molecule screening identifies the selanazal drug ebselen as a potent inhibitor of DMT1-mediated iron uptake

1 reference

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29 September 2017

Confluent monolayers of cultured human fetal retinal pigment epithelium exhibit morphology and physiology of native tissue.

1 reference

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29 September 2017

Mitochondrial involvement in genetically determined transition metal toxicity I. Iron toxicity.

1 reference

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29 September 2017

Nitrogen monoxide (NO)-mediated iron release from cells is linked to NO-induced glutathione efflux via multidrug resistance-associated protein 1.

1 reference

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29 September 2017

Heat shock protein 27 downregulates the transferrin receptor 1-mediated iron uptake

1 reference

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29 September 2017

(R)-alpha-lipoic acid protects retinal pigment epithelial cells from oxidative damage

1 reference

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29 September 2017

Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration

1 reference

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29 September 2017

Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid

1 reference

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29 September 2017

Characterization of beta amyloid assemblies in drusen: the deposits associated with aging and age-related macular degeneration

1 reference

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29 September 2017

Iron Accumulation During Cellular Senescence in Human FibroblastsIn Vitro

1 reference

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29 September 2017

Maculas affected by age-related macular degeneration contain increased chelatable iron in the retinal pigment epithelium and Bruch's membrane.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597693

29 September 2017

Age-related macular degeneration a new viewpoint

1 reference

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29 September 2017

Retinal oxygen: fundamental and clinical aspects

1 reference

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29 September 2017

Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration

1 reference

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29 September 2017

Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival

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29 September 2017

Common eye diseases of elderly people: identifying and treating causes of vision loss

1 reference

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29 September 2017

Molecular bases of cellular iron toxicity

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29 September 2017

Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats.

1 reference

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29 September 2017

The role of heme and iron-sulfur clusters in mitochondrial biogenesis, maintenance, and decay with age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597693

29 September 2017

N-t-Butyl hydroxylamine is an antioxidant that reverses age-related changes in mitochondria in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597693

29 September 2017

The role of oxidative stress in the pathogenesis of age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597693

29 September 2017

A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597693

29 September 2017

Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597693

29 September 2017

Glutathione in human plasma: decline in association with aging, age-related macular degeneration, and diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597693

29 September 2017

Lipofuscin of the retinal pigment epithelium: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597693

29 September 2017

Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group

1 reference

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29 September 2017

Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins

1 reference

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29 September 2017

Chemistry and metabolism of lipids in the vertebrate retina

1 reference

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29 September 2017

Familial apoceruloplasmin deficiency associated with blepharospasm and retinal degeneration

1 reference

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29 September 2017

Oxygen radical chemistry of polyunsaturated fatty acids

1 reference

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29 September 2017

Iron toxicity and oxygen radicals

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597693

29 September 2017

Evaluation of oxidative processes in human pigment epithelial cells associated with retinal outer segment phagocytosis

1 reference

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29 September 2017

Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis

1 reference

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27 June 2018

N-t-butyl hydroxylamine, a hydrolysis product of alpha-phenyl-N-t-butyl nitrone, is more potent in delaying senescence in human lung fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597693

27 June 2018

Copper, iron and zinc in Alzheimer's disease senile plaques.

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27 June 2018

Iron homeostasis, oxidative stress, and DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597693

27 June 2018

Hereditary ceruloplasmin deficiency with hemosiderosis: a clinicopathological study of a Japanese family

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27 June 2018

Posterior penetrating injury in the rabbit eye: effect of blood and ferrous ions

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27 June 2018

N-t-Butyl hydroxylamine regulates heat shock-induced apoptosis in U937 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597693

4 September 2018

Mitochondrial alterations of retinal pigment epithelium in age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597693

4 September 2018

Macular degeneration in a patient with aceruloplasminemia, a disease associated with retinal iron overload

1 reference

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4 September 2018

Immunolocalization and regulation of iron handling proteins ferritin and ferroportin in the retina

1 reference

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4 September 2018

The use of N-t-butyl hydroxylamine for radioprotection in cultured cells and mice

1 reference

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4 September 2018

Iron accumulation, iron-mediated toxicity and altered levels of ferritin and transferrin receptor in cultured astrocytes during incubation with ferric ammonium citrate.

1 reference

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4 September 2018

Impaired retinal iron homeostasis associated with defective phagocytosis in Royal College of Surgeons rats

1 reference

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4 September 2018

Quantitative analysis of cell death and ferritin expression in response to cortical iron: implications for hypoxia-ischemia and stroke

1 reference

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4 September 2018

Risk factors for age-related macular degeneration: Pooled findings from three continents.

1 reference

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4 September 2018

Chemically de-acetylated 2',7'-dichlorodihydrofluorescein diacetate as a probe of respiratory burst activity in mononuclear phagocytes

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4 September 2018

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1 reference

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4 September 2018

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4 September 2018

Fluorescence analysis of the labile iron pool of mammalian cells.

1 reference

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4 September 2018

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4 September 2018

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transformation and cytotoxicity of iron in siderosis bulbi

1 reference

https://pubmed.ncbi.nlm.nih.gov/17656467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental study of the retinal toxicity of hemoglobinic iron

1 reference

https://pubmed.ncbi.nlm.nih.gov/17656467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-performance liquid chromatography of thiols and disulfides: dinitrophenol derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/17656467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release of iron by human retinal pigment epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17656467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of aging and acetyl-L-carnitine on the activity of cytochrome oxidase and adenine nucleotide translocase in rat heart mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17656467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron-induced apoptosis in the photoreceptor cells of rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17656467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cytochrome c oxidase activity by 4-hydroxynonenal (HNE). Role of HNE adduct formation with the enzyme subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/17656467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease and age-related macular degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/17656467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron, ferritin, transferrin, and transferrin receptor in the adult rat retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/17656467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron levels in human retina: sex difference and increase with age

1 reference

https://pubmed.ncbi.nlm.nih.gov/17656467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1096/FJ.07-8396COM

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17656467%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17656467%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17656467%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

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