(Q37008856)

17 August 2017

Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production (English)

1 reference

17 August 2017

0 references

1 reference

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Paul M Titchenell

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

William J Quinn

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Mingjian Lu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Qingwei Chu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Wenyun Lu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Changhong Li

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Helen Chen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Bobby R Monks

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Julia Chen

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Joshua D Rabinowitz

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

publication date

26 May 2016

1 reference

17 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

1154-1166

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization

7 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Hepatic insulin signalling is dispensable for suppression of glucose output by insulin in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Decreased expression of hepatic glucokinase in type 2 diabetes.

29 September 2017

1 reference

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Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes

29 September 2017

1 reference

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Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors.

29 September 2017

1 reference

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Deletion of hepatic FoxO1/3/4 genes in mice significantly impacts on glucose metabolism through downregulation of gluconeogenesis and upregulation of glycolysis

29 September 2017

1 reference

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Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP

29 September 2017

1 reference

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Strategies for the design of hepatoselective glucokinase activators to treat type 2 diabetes

29 September 2017

1 reference

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Central nervous system control of metabolism.

29 September 2017

1 reference

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Regulation of hepatic glucose uptake and storage in vivo

29 September 2017

1 reference

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Evidence against a physiologic role for acute changes in CNS insulin action in the rapid regulation of hepatic glucose production

29 September 2017

1 reference

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FoxO1 inhibits sterol regulatory element-binding protein-1c (SREBP-1c) gene expression via transcription factors Sp1 and SREBP-1c

29 September 2017

1 reference

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Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover

29 September 2017

1 reference

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Dissociation of the glucose and lipid regulatory functions of FoxO1 by targeted knockin of acetylation-defective alleles in mice

29 September 2017

1 reference

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Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Metabolomic analysis and visualization engine for LC-MS data

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Akt2 is required for hepatic lipid accumulation in models of insulin resistance.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Restoration of hepatic glucokinase expression corrects hepatic glucose flux and normalizes plasma glucose in zucker diabetic fatty rats

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation

29 September 2017

1 reference

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Selective versus total insulin resistance: a pathogenic paradox

29 September 2017

1 reference

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Aberrant Forkhead box O1 function is associated with impaired hepatic metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism

29 September 2017

1 reference

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Critical nodes in signalling pathways: insights into insulin action

29 September 2017

1 reference

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A brain-liver circuit regulates glucose homeostasis

29 September 2017

1 reference

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Hypothalamic K(ATP) channels control hepatic glucose production

29 September 2017

1 reference

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PKC-theta knockout mice are protected from fat-induced insulin resistance

29 September 2017

1 reference

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Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle

29 September 2017

1 reference

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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

29 September 2017

1 reference

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Prevention of fat-induced insulin resistance by salicylate

29 September 2017

1 reference

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Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Correction of diabetic alterations by glucokinase.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Insulin's direct effects on the liver dominate the control of hepatic glucose production

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

A noncanonical, GSK3-independent pathway controls postprandial hepatic glycogen deposition

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Nutrient control of phosphorylation and translocation of Foxo1 in C57BL/6 and db/db mice.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

A glucose sensor role for glucokinase in anterior pituitary cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Phenotypic correction of diabetic mice by adenovirus-mediated glucokinase expression

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

Free fatty acid as a link in the regulation of hepatic glucose output by peripheral insulin

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4909537

The direct and indirect effects of insulin on hepatic glucose production in vivo

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27238637

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2016.04.022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27238637%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference