(Q37008886)

17 August 2017

1 reference

title

Drug transport across the placenta, role of the ABC drug efflux transporters (English)

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17 August 2017

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Javad Behravan

1

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17 August 2017

Micheline Piquette-Miller

series ordinal

2

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17 August 2017

language of work or name

English

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publication date

1 December 2007

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Expert Opinion on Drug Metabolism & Toxicology

17 August 2017

published in

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17 August 2017

volume

3

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17 August 2017

issue

6

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17 August 2017

page(s)

819-830

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Transport of glyburide by placental ABC transporters: implications in fetal drug exposure.

17 August 2017

cites work

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Techniques to study human placental transport.

21 January 2018

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Development of structures and transport functions in the mouse placenta

21 January 2018

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Hormonal regulation of glucose and system A amino acid transport in first trimester placental villous fragments

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Efflux transporters of the human placenta

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Drug transfer and metabolism by the human placenta.

21 January 2018

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Drug use in pregnancy: an overview of epidemiological (drug utilization) studies

21 January 2018

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Antimalarial drugs and pregnancy: safety, pharmacokinetics, and pharmacovigilance.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.3.6.819

The safety of artemisinins during pregnancy: a pressing question

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Placental toxicology: tobacco smoke, abused drugs, multiple chemical interactions, and placental function

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Thalidomide and the Titanic: reconstructing the technology tragedies of the twentieth century.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Dermatologic agents during pregnancy and lactation: an update and clinical review

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Accelerated metabolism of nicotine and cotinine in pregnant smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Pharmacokinetics of fluoxetine and norfluoxetine in pregnancy and lactation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Citalopram in pregnancy and lactation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Ex vivo human placenta models: transport of immunoglobulin G and its subclasses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Designing pregnancy centered medications: drugs which do not cross the human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Culture of syncytiotrophoblast for the study of human placental transfer. Part I: Isolation and purification of cytotrophoblast

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Syncytiotrophoblast is a barrier to maternal-fetal transmission of herpes simplex virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Mechanisms of chloride transport across the syncytiotrophoblast basal membrane in the human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Isoforms of amino acid transporters in placental syncytiotrophoblast: plasma membrane localization and potential role in maternal/fetal transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Nutrient transport across the placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Comparative placental structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Basal Membrane Localization of MRP1 in Human Placental Trophoblast

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Sites of mRNA expression of the cystic fibrosis (CF) and multidrug resistance (MDR1) genes in the human placenta of early pregnancy: No evidence for complementary expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Conditionally immortalized syncytiotrophoblast cell lines as new tools for study of the blood-placenta barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Human placental trophoblast culture: One-sided and two-sided models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Culture of syncytiotrophoblast for the study of human placental transfer. Part II: Production, culture and use of syncytiotrophoblast

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Pharmacophore-based discovery of ligands for drug transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Isolation and expression of a complementary DNA that confers multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Functional expression and localization of P-glycoprotein at the blood brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Expression of P-glycoprotein in human cerebral cortex microvessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

P-glycoprotein and breast cancer resistance protein expression in human placentae of various gestational ages

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Role of MDR1 and MRP1 in trophoblast cells, elucidated using retroviral gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Mammalian ABC transporters in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

P-glycoprotein deficiency in a subpopulation of CF-1 mice enhances avermectin-induced neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Multidrug resistance and the role of P-glycoprotein knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Human placental transport of vinblastine, vincristine, digoxin and progesterone: contribution of P-glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Area/moment and compartmental modeling of pharmacokinetics during pregnancy: applications to maternal/fetal exposures to corticosteroids in sheep and rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Explaining interindividual variability of docetaxel pharmacokinetics and pharmacodynamics in Asians through phenotyping and genotyping strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

The MRP family of drug efflux pumps

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Folate concentration dependent transport activity of the Multidrug Resistance Protein 1 (ABCC1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Folate deprivation results in the loss of breast cancer resistance protein (BCRP/ABCG2) expression. A role for BCRP in cellular folate homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Transport function and substrate specificity of multidrug resistance protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Arsenic transport by the human multidrug resistance protein 1 (MRP1/ABCC1). Evidence that a tri-glutathione conjugate is required

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

The canalicular multispecific organic anion transporter and conjugated hyperbilirubinemia in rat and man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Variable expression of MRP2 (ABCC2) in human placenta: influence of gestational age and cellular differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

A family of drug transporters: the multidrug resistance-associated proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Tissue distribution and induction of human multidrug resistant protein 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

MRP3, an organic anion transporter able to transport anti-cancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Analysis of the structure and expression pattern of MRP7 (ABCC10), a new member of the MRP subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Analysis of the drug resistance profile of multidrug resistance protein 7 (ABCC10): resistance to docetaxel

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

A multidrug resistance transporter from human MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Characterization of oligomeric human half-ABC transporter ATP-binding cassette G2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Stage-specific distribution of P-glycoprotein in first-trimester and full-term human placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Effects of maturation on RNA transcription and protein expression of four MRP genes in human placenta and in BeWo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Expression level of ABCG2 in the placenta decreases from the mid stage to the end of gestation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Lipopolysaccharide treatment downregulates the expression of the pregnane X receptor, cyp3a11 and mdr1a genes in mouse placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

TNF-alpha is a predictor of insulin resistance in human pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Multidrug resistance phosphoglycoprotein (ABCB1) in the mouse placenta: fetal protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Estrogen-mediated post transcriptional down-regulation of P-glycoprotein in MDR1-transduced human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Breast cancer resistance protein (Bcrp1/Abcg2) in mouse placenta and yolk sac: ontogeny and its regulation by progesterone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

The functions and structure of ABC transporters: implications for the design of new inhibitors of Pgp and MRP1 to control multidrug resistance (MDR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Transplacental treatment of fetal tachycardia: implications of drug transporting proteins in placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Rapid Identification of P-glycoprotein Substrates and Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

21 January 2018

Identifiers

DOI

10.1517/17425255.3.6.819

1 reference

17 August 2017

1 reference