(Q37010058)

English

Frequent truncating mutation of TFAM induces mitochondrial DNA depletion and apoptotic resistance in microsatellite-unstable colorectal cancer

scientific article published on 05 April 2011

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scholarly article

1 reference

Europe PubMed Central

17 August 2017

Frequent truncating mutation of TFAM induces mitochondrial DNA depletion and apoptotic resistance in microsatellite-unstable colorectal cancer (English)

1 reference

Europe PubMed Central

17 August 2017

apoptotic process

0 references

mitochondrial DNA

0 references

1 reference

based on heuristic

inferred from title

colorectal cancer

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

4

object named as

Xianshu Wang

1 reference

Europe PubMed Central

17 August 2017

author name string

Jianhui Guo

1

1 reference

Europe PubMed Central

17 August 2017

Li Zheng

2

1 reference

Europe PubMed Central

17 August 2017

Wenyong Liu

3

1 reference

Europe PubMed Central

17 August 2017

Zemin Wang

5

1 reference

Europe PubMed Central

17 August 2017

Zehua Wang

6

1 reference

Europe PubMed Central

17 August 2017

Amy J French

7

1 reference

Europe PubMed Central

17 August 2017

Dongchon Kang

8

1 reference

Europe PubMed Central

17 August 2017

Lin Chen

9

1 reference

Europe PubMed Central

17 August 2017

Stephen N Thibodeau

10

1 reference

Europe PubMed Central

17 August 2017

Wanguo Liu

11

1 reference

Europe PubMed Central

17 August 2017

language of work or name

0 references

publication date

5 April 2011

1 reference

Europe PubMed Central

17 August 2017

Cancer Research

1 reference

Europe PubMed Central

17 August 2017

71

1 reference

Europe PubMed Central

17 August 2017

2978-2987

1 reference

Europe PubMed Central

17 August 2017

8

1 reference

Europe PubMed Central

17 August 2017

Mutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt/Dvl/beta-catenin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Mismatch repair protein deficiency compromises cisplatin-induced apoptotic signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

The conserved translocase Tim17 prevents mitochondrial DNA loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Functional genetic screening reveals the role of mitochondrial cytochrome b as a mediator of FAS-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Platinum resistance: the role of DNA repair pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Mitochondrial transcription factor A (TFAM): roles in maintenance of mtDNA and cellular functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons

1 reference

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29 September 2017

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

1 reference

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29 September 2017

Mitochondrial DNA mutations in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Architectural role of mitochondrial transcription factor A in maintenance of human mitochondrial DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

A switch in metabolism precedes increased mitochondrial biogenesis in respiratory chain-deficient mouse hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

P53 physically interacts with mitochondrial transcription factor A and differentially regulates binding to damaged DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Mutations at coding repeat sequences in mismatch repair-deficient human cancers: toward a new concept of target genes for instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Inverse relationship between microsatellite instability and K-ras and p53 gene alterations in colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Increased in vivo apoptosis in cells lacking mitochondrial DNA gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Binding of human mitochondrial transcription factor A, an HMG box protein, to a four-way DNA junction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Genetic modification of survival in tissue-specific knockout mice with mitochondrial cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Denaturing high performance liquid chromatography (DHPLC) used in the detection of germline and somatic mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

DNA methylation and genetic instability in colorectal cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Microsatellite instability in cancer of the proximal colon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

29 September 2017

The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

27 June 2018

The role of DNA mismatch repair in drug resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

27 June 2018

Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

27 June 2018

Microsatellite instability, mismatch repair deficiency, and BRAF mutation in treatment-resistant germ cell tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

4 September 2018

Mitochondrial transcription factor A regulates mtDNA copy number in mammals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

4 September 2018

Oxidative stress-related alteration of the copy number of mitochondrial DNA in human leukocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

4 September 2018

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

4 September 2018

The C-terminal Tail of Mitochondrial Transcription Factor A Markedly Strengthens its General Binding to DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710668

4 December 2018

Methods for assessing binding of mitochondrial transcription factor A (TFAM) to DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/21467167

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA binding properties of recombinant human mitochondrial transcription factor 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21467167

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of cell cycle status and E2F complexes in mobilized CD34+ cells before and after cytokine stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21467167

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial genome instability and mtDNA depletion in human cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/21467167

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-10-3482

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

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