(Q37023053)

English

Hepatic stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not ceramide concentrations are increased in the nonalcoholic human fatty liver

scientific article published on 24 October 2008

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scholarly article

1 reference

Europe PubMed Central

17 August 2017

Hepatic stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not ceramide concentrations are increased in the nonalcoholic human fatty liver (English)

1 reference

Europe PubMed Central

17 August 2017

1 reference

based on heuristic

inferred from title

Tuulikki Seppänen-Laakso

2

object named as

Tuulikki Seppänen-Laakso

0 references

object named as

Matej Oresic

7

0 references

Hannele Yki-Järvinen

8

object named as

Hannele Yki-Järvinen

1 reference

Europe PubMed Central

17 August 2017

5

object named as

Johanna Arola

1 reference

Europe PubMed Central

17 August 2017

1

object named as

Anna Kotronen

1 reference

Europe PubMed Central

17 August 2017

Anna-Liisa Ruskeepää

6

object named as

Anna-Liisa Ruskeepää

1 reference

Europe PubMed Central

17 August 2017

Jukka Westerbacka

3

object named as

Jukka Westerbacka

1 reference

Europe PubMed Central

17 August 2017

Tuula Kiviluoto

4

object named as

Tuula Kiviluoto

1 reference

Europe PubMed Central

17 August 2017

language of work or name

0 references

publication date

24 October 2008

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

58

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Europe PubMed Central

17 August 2017

203-208

1 reference

Europe PubMed Central

17 August 2017

1

1 reference

Europe PubMed Central

17 August 2017

Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606873

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Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance

1 reference

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Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis

1 reference

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Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

1 reference

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1 reference

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Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction

1 reference

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Thematic review series: patient-oriented research. Recent advances in liver triacylglycerol and fatty acid metabolism using stable isotope labeling techniques

1 reference

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MZmine: toolbox for processing and visualization of mass spectrometry based molecular profile data

1 reference

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29 September 2017

Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans

1 reference

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Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease

1 reference

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Mechanisms of regulation of gene expression by fatty acids

1 reference

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PKC-theta knockout mice are protected from fat-induced insulin resistance

1 reference

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Structure, function, and dietary regulation of delta6, delta5, and delta9 desaturases

1 reference

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Site and mechanism of leptin action in a rodent form of congenital lipodystrophy

1 reference

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29 September 2017

Regulation of stearoyl-CoA desaturases and role in metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606873

29 September 2017

Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference

1 reference

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29 September 2017

Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity

1 reference

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29 September 2017

Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss

1 reference

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29 September 2017

Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells

1 reference

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29 September 2017

The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1

1 reference

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29 September 2017

Molecular characterization of human acetyl-CoA synthetase, an enzyme regulated by sterol regulatory element-binding proteins

1 reference

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29 September 2017

Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606873

29 September 2017

Sterol regulatory element binding protein-1 expression is suppressed by dietary polyunsaturated fatty acids. A mechanism for the coordinate suppression of lipogenic genes by polyunsaturated fats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606873

29 September 2017

Sterol regulation of acetyl coenzyme A carboxylase promoter requires two interdependent binding sites for sterol regulatory element binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606873

29 September 2017

Biosynthesis of triacylglycerols

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606873

29 September 2017

Human fatty acid synthesis is stimulated by a eucaloric low fat, high carbohydrate diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606873

29 September 2017

A model cell line to study regulation of stearoyl-CoA desaturase gene 1 expression by insulin and polyunsaturated fatty acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606873

29 September 2017

Diacylglycerol/protein kinase C signalling: a mechanism for insulin resistance?

1 reference

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Protein kinase C is increased in the liver of humans and rats with non-insulin-dependent diabetes mellitus: an alteration not due to hyperglycemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606873

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Evaluation of methods for the measurement of low-density lipoprotein cholesterol.

1 reference

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Parallel activation of de novo lipogenesis and stearoyl-CoA desaturase activity after 3 d of high-carbohydrate feeding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606873

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Quantitative lipid analysis of human liver needle biopsy specimens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606873

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Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.

1 reference

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Determination of free and total insulin and C-peptide in insulin-treated diabetics

1 reference

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Effect of liver fat on insulin clearance.

1 reference

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Long term nutritional intake and the risk for non-alcoholic fatty liver disease (NAFLD): a population based study

1 reference

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A lipidomic analysis of nonalcoholic fatty liver disease.

1 reference

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Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity.

1 reference

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Prolonged n-3 polyunsaturated fatty acid supplementation ameliorates hepatic steatosis in patients with non-alcoholic fatty liver disease: a pilot study.

1 reference

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Overproduction of large VLDL particles is driven by increased liver fat content in man.

1 reference

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Temporal pattern of de novo lipogenesis in the postprandial state in healthy men.

1 reference

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Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated receptor-alpha.

1 reference

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Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms

1 reference

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Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease

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Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis

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A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis

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Hepatic secretion of VLDL fatty acids during stimulated lipogenesis in men.

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Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver

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Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acid-induced skeletal muscle insulin resistance in vitro

1 reference

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12 December 2020

based on heuristic

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Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18952834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid composition of human liver biopsy specimens

1 reference

https://pubmed.ncbi.nlm.nih.gov/18952834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in the expression and cellular localization of protein kinase C isozymes epsilon and theta are associated with insulin resistance in skeletal muscle of the high-fat-fed rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/18952834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of hepatic lipogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18952834

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DB08-1074

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

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