(Q37039071)

English

Ectodomain cleavage of the EGF ligands HB-EGF, neuregulin1-beta, and TGF-alpha is specifically triggered by different stimuli and involves different PKC isoenzymes

scientific article published on 29 August 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Ectodomain cleavage of the EGF ligands HB-EGF, neuregulin1-beta, and TGF-alpha is specifically triggered by different stimuli and involves different PKC isoenzymes (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

membrane protein ectodomain proteolysis

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

5

object named as

Harvey Lodish

1 reference

Europe PubMed Central

17 August 2017

PMC publication ID

author name string

Andreas Herrlich

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Eva Klinman

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Jonathan Fu

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Cameron Sadegh

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

0 references

publication date

29 August 2008

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

22

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

4281-4295

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Enhancement of alpha-secretase cleavage of amyloid precursor protein by a metalloendopeptidase nardilysin.

1 reference

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ADAMs in cancer cell proliferation and progression.

1 reference

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Targeting TACE-dependent EGFR ligand shedding in breast cancer

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Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx

1 reference

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29 September 2017

Nardilysin enhances ectodomain shedding of heparin-binding epidermal growth factor-like growth factor through activation of tumor necrosis factor-alpha-converting enzyme

1 reference

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ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors

1 reference

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ADAMs, cell migration and cancer

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Phosphorylation of TNF-alpha converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation.

1 reference

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29 September 2017

Cytoplasmic domain phosphorylation of heparin-binding EGF-like growth factor.

1 reference

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29 September 2017

ADAM-mediated ectodomain shedding of HB-EGF in receptor cross-talk

1 reference

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G protein coupling and second messenger generation are indispensable for metalloprotease-dependent, heparin-binding epidermal growth factor shedding through angiotensin II type-1 receptor

1 reference

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ERBB receptors and cancer: the complexity of targeted inhibitors

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29 September 2017

Role of proneuregulin 1 cleavage and human epidermal growth factor receptor activation in hypertonic aquaporin induction

1 reference

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29 September 2017

ADAM binding protein Eve-1 is required for ectodomain shedding of epidermal growth factor receptor ligands

1 reference

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29 September 2017

Cell-matrix interaction via CD44 is independently regulated by different metalloproteinases activated in response to extracellular Ca(2+) influx and PKC activation

1 reference

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29 September 2017

Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor

1 reference

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29 September 2017

A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model

1 reference

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29 September 2017

Beta-secretase inhibition for the treatment of Alzheimer's disease--promise and challenge

1 reference

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29 September 2017

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands

1 reference

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29 September 2017

Matrix metalloproteinase inhibitor development and the remodeling of drug discovery

1 reference

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29 September 2017

EGFR signal transactivation in cancer cells

1 reference

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29 September 2017

Neuropeptide-induced transactivation of a neuronal epidermal growth factor receptor is mediated by metalloprotease-dependent formation of heparin-binding epidermal growth factor

1 reference

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29 September 2017

Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking

1 reference

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29 September 2017

PACSIN3 binds ADAM12/meltrin alpha and up-regulates ectodomain shedding of heparin-binding epidermal growth factor-like growth factor

1 reference

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TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells

1 reference

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Neuregulins: functions, forms, and signaling strategies

1 reference

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TACE is required for the activation of the EGFR by TGF-alpha in tumors

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New functions for the matrix metalloproteinases in cancer progression

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How matrix metalloproteinases regulate cell behavior

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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4 September 2018

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy

1 reference

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A dual signaling cascade that regulates the ectodomain shedding of heparin-binding epidermal growth factor-like growth factor

1 reference

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1 reference

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4 December 2018

An essential role for ectodomain shedding in mammalian development

1 reference

https://pubmed.ncbi.nlm.nih.gov/18757500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential shedding of transmembrane neuregulin isoforms by the tumor necrosis factor-alpha-converting enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/18757500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors: a co-culture system for identifying intermediates upstream and downstream of heparin-binding EGF shedding

1 reference

https://pubmed.ncbi.nlm.nih.gov/18757500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1096/FJ.08-113852

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

ResearchGate publication ID

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