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Analysis of re-replication from deregulated origin licensing by DNA fiber spreading
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Europe PubMed Central
PMC publication ID
2615611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19010964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
title
Analysis of re-replication from deregulated origin licensing by DNA fiber spreading
(English)
1 reference
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Europe PubMed Central
PMC publication ID
2615611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19010964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
author
Jeanette Gowen Cook
series ordinal
4
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Europe PubMed Central
PMC publication ID
2615611
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19010964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
author name string
Elizabeth S Dorn
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1
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Europe PubMed Central
PMC publication ID
2615611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19010964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Paul D Chastain
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2
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PMC publication ID
2615611
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19010964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Jonathan R Hall
series ordinal
3
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Europe PubMed Central
PMC publication ID
2615611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19010964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
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English
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publication date
14 November 2008
1 reference
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Europe PubMed Central
PMC publication ID
2615611
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19010964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
published in
Nucleic Acids Research
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stated in
Europe PubMed Central
PMC publication ID
2615611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19010964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
volume
37
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Europe PubMed Central
PMC publication ID
2615611
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19010964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
issue
1
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Europe PubMed Central
PMC publication ID
2615611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19010964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
page(s)
60-69
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Europe PubMed Central
PMC publication ID
2615611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19010964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
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ImageJ
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Europe PubMed Central
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2615611/fullTextXML
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cites work
Cdt1 and Cdc6 are destabilized by rereplication-induced DNA damage.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
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29 September 2017
Overreplication of short DNA regions during S phase in human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
The ATR-mediated S phase checkpoint prevents rereplication in mammalian cells when licensing control is disrupted.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
ATR pathway is the primary pathway for activating G2/M checkpoint induction after re-replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
The Mre11/Rad50/Nbs1 complex plays an important role in the prevention of DNA rereplication in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
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29 September 2017
Cell cycle regulation of DNA replication.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Cdc6 stability is regulated by the Huwe1 ubiquitin ligase after DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
The intra-S-phase checkpoint affects both DNA replication initiation and elongation: single-cell and -DNA fiber analyses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Unscheduled DNA replication origin activation at inserted HPV 18 sequences in a HPV-18/MYC amplicon
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Strength in numbers: preventing rereplication via multiple mechanisms in eukaryotic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
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29 September 2017
Cdc7-Dbf4 and the human S checkpoint response to UVC
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Distinct action of the retinoblastoma pathway on the DNA replication machinery defines specific roles for cyclin-dependent kinase complexes in prereplication complex assembly and S-phase progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Right place, right time, and only once: replication initiation in metazoans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Disruption of mechanisms that prevent rereplication triggers a DNA damage response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Preventing re-replication of chromosomal DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Degradation of Cdt1 during S phase is Skp2-independent and is required for efficient progression of mammalian cells through S phase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Functional domains of the Xenopus replication licensing factor Cdt1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Regulation of early events in chromosome replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Loss of Geminin induces rereplication in the presence of functional p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
The regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
A p53-dependent checkpoint pathway prevents rereplication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
DNA replication in eukaryotic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Control of DNA replication and chromosome ploidy by geminin and cyclin A
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Oncogenic potential of the DNA replication licensing protein CDT1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
E2Fs up-regulate expression of genes involved in DNA replication, DNA repair and mitosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Amplification of the human dihydrofolate reductase gene via double minutes is initiated by chromosome breaks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
E2F3 activity is regulated during the cell cycle and is required for the induction of S phase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Normal diploid human and rodent cells lack a detectable frequency of gene amplification
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
29 September 2017
Replication fork density increases during DNA synthesis in X. laevis egg extracts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
27 June 2018
Cyclin a is required for the onset of DNA replication in mammalian fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
27 June 2018
Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
4 September 2018
Checkpoint regulation of replication dynamics in UV-irradiated human cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2615611
retrieved
4 September 2018
Role for cyclin A in the dependence of mitosis on completion of DMA replication
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19010964
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
DNA double labelling with IdUrd and CldUrd for spatial and temporal analysis of cell proliferation and DNA replication
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19010964
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/NAR/GKN912
1 reference
stated in
Europe PubMed Central
PMC publication ID
2615611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19010964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
PMC publication ID
2615611
1 reference
stated in
Europe PubMed Central
PMC publication ID
2615611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19010964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
PubMed publication ID
19010964
1 reference
stated in
Europe PubMed Central
PMC publication ID
2615611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19010964%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
ResearchGate publication ID
23475297
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