(Q37043008)

English

Synergistic combination therapy with nanoliposomal C6-ceramide and vinblastine is associated with autophagy dysfunction in hepatocarcinoma and colorectal cancer models

scientific article published on 07 May 2013

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scholarly article

1 reference

Europe PubMed Central

17 August 2017

Synergistic combination therapy with nanoliposomal C6-ceramide and vinblastine is associated with autophagy dysfunction in hepatocarcinoma and colorectal cancer models (English)

1 reference

Europe PubMed Central

17 August 2017

0 references

colorectal cancer

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

colorectal carcinoma

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

9

object named as

Mark Kester

1 reference

Europe PubMed Central

17 August 2017

Jeffrey D Clogston

2

object named as

Jeffrey D Clogston

1 reference

Europe PubMed Central

17 August 2017

author name string

Pavan P Adiseshaiah

1

1 reference

Europe PubMed Central

17 August 2017

Christopher B McLeland

3

1 reference

Europe PubMed Central

17 August 2017

Jamie Rodriguez

4

1 reference

Europe PubMed Central

17 August 2017

Timothy M Potter

5

1 reference

Europe PubMed Central

17 August 2017

Barry W Neun

6

1 reference

Europe PubMed Central

17 August 2017

Sarah L Skoczen

7

1 reference

Europe PubMed Central

17 August 2017

Sriram S Shanmugavelandy

8

1 reference

Europe PubMed Central

17 August 2017

Stephan T Stern

10

1 reference

Europe PubMed Central

17 August 2017

Scott E McNeil

11

1 reference

Europe PubMed Central

17 August 2017

language of work or name

0 references

publication date

7 May 2013

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Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

337

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Europe PubMed Central

17 August 2017

2

1 reference

Europe PubMed Central

17 August 2017

254-265

1 reference

Europe PubMed Central

17 August 2017

Autophagy in lysosomal storage disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Pharmacological control of autophagy: therapeutic perspectives in inflammatory bowel disease and colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Induction of Mitochondrial Pathways and Endoplasmic Reticulum Stress for Increasing Apoptosis in Ectopic and Orthotopic Neuroblastoma Xenografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Sustained antitumor activity by co-targeting mTOR and the microtubule with temsirolimus/vinblastine combination in hepatocellular carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Autophagy regulation in cancer development and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Principles and current strategies for targeting autophagy for cancer treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Monitoring nanoparticle-treated hepatocarcinoma cells for apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Acetylated microtubules are required for fusion of autophagosomes with lysosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Autophagy and aging: lessons from progeria models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Fullerenol cytotoxicity in kidney cells is associated with cytoskeleton disruption, autophagic vacuole accumulation, and mitochondrial dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Targeting of survivin by nanoliposomal ceramide induces complete remission in a rat model of NK-LGL leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Augmentation of therapeutic efficacy in drug-resistant tumor models using ceramide coadministration in temporal-controlled polymer-blend nanoparticle delivery systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Chloroquine and its analogs: a new promise of an old drug for effective and safe cancer therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Ceramide starves cells to death by downregulating nutrient transporter proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Down-regulation of Bax-interacting factor-1 in colorectal adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Induction of autophagy in porcine kidney cells by quantum dots: a common cellular response to nanomaterials?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Autophagy: from phenomenology to molecular understanding in less than a decade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Combined therapeutic effects of vinblastine and rapamycin on human neuroblastoma growth, apoptosis, and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Loss of autophagy in the central nervous system causes neurodegeneration in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

The role of autophagy in cancer development and response to therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Systemic delivery of liposomal short-chain ceramide limits solid tumor growth in murine models of breast adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Liposomal delivery enhances short-chain ceramide-induced apoptosis of breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Induction of autophagy and inhibition of tumorigenesis by beclin 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

29 September 2017

Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

27 June 2018

Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

27 June 2018

Purification of autophagosomes from rat hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

4 September 2018

Rapid distribution of liposomal short-chain ceramide in vitro and in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

4 September 2018

Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722309

4 December 2018

Vinblastine-induced phosphorylation of Bcl-2 and Bcl-XL is mediated by JNK and occurs in parallel with inactivation of the Raf-1/MEK/ERK cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/23664889

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of autophagic vacuoles from rat kidney cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/23664889

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nanoliposomal ceramide prevents in vivo growth of hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23664889

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of cytotoxicity of nanoparticulate materials in porcine kidney cells and human hepatocarcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23664889

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.CANLET.2013.04.034

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

1 reference

Europe PubMed Central

17 August 2017

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