(Q37044525)

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In vitro and in vivo study of epigallocatechin-3-gallate-induced apoptosis in aerobic glycolytic hepatocellular carcinoma cells involving inhibition of phosphofructokinase activity.

scientific article published on 28 June 2016

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16 March 2020

In vitro and in vivo study of epigallocatechin-3-gallate-induced apoptosis in aerobic glycolytic hepatocellular carcinoma cells involving inhibition of phosphofructokinase activity (English)

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16 March 2020

hepatocellular carcinoma

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16 March 2020

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Shunfeng Zhou

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Sainan Li

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Liwei Wu

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Jiao Feng

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Jingjing Li

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Tong Liu

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Rong Zhang

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Shizan Xu

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Yuqing Zhou

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Rui Kong

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Fan Wang

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Jie Lu

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Scientific Reports

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16 March 2020

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28 June 2016

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Epigallocatechin-3-gallate attenuates apoptosis and autophagy in concanavalin A-induced hepatitis by inhibiting BNIP3.

1 reference

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Metabolomics Identifies Biomarker Pattern for Early Diagnosis of Hepatocellular Carcinoma: from Diethylnitrosamine Treated Rats to Patients.

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Astaxanthin Inhibits Proliferation and Induces Apoptosis of Human Hepatocellular Carcinoma Cells via Inhibition of Nf-Κb P65 and Wnt/Β-Catenin in Vitro.

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AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest

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Metabolic Consequences of LDHA inhibition by Epigallocatechin Gallate and Oxamate in MIA PaCa-2 Pancreatic Cancer Cells

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By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice.

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Genetic variants in de novo lipogenic pathway genes predict the prognosis of surgically-treated hepatocellular carcinoma

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A weighted relative difference accumulation algorithm for dynamic metabolomics data: long-term elevated bile acids are risk factors for hepatocellular carcinoma

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Suppression of CYP2C9 by microRNA hsa-miR-128-3p in human liver cells and association with hepatocellular carcinoma.

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29 September 2017

Epigallocatechin gallate inhibits human tongue carcinoma cells via HK2‑mediated glycolysis

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Diagnostic Performance of Des-γ-carboxy Prothrombin for Hepatocellular Carcinoma: A Meta-Analysis

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29 September 2017

Fructose-2,6-bisphosphate synthesis by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth

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29 September 2017

Phosphofructokinase: a mediator of glycolytic flux in cancer progression

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29 September 2017

The synergistic in vitro and in vivo antitumor effect of combination therapy with salinomycin and 5-fluorouracil against hepatocellular carcinoma

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29 September 2017

EGCG enhances the efficacy of cisplatin by downregulating hsa-miR-98-5p in NSCLC A549 cells

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29 September 2017

Anti-miR-197 inhibits migration in HCC cells by targeting KAI 1/CD82.

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29 September 2017

EGCG attenuates autoimmune arthritis by inhibition of STAT3 and HIF-1α with Th17/Treg control

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29 September 2017

Ethyl pyruvate inhibits proliferation and induces apoptosis of hepatocellular carcinoma via regulation of the HMGB1-RAGE and AKT pathways.

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29 September 2017

Genistein inhibits hepatocellular carcinoma cell migration by reversing the epithelial-mesenchymal transition: partial mediation by the transcription factor NFAT1.

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29 September 2017

Green tea polyphenol, (-)-epigallocatechin-3-gallate, induces toxicity in human skin cancer cells by targeting β-catenin signaling

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29 September 2017

Green tea polyphenol epigallocatechin-3-gallate (EGCG) as adjuvant in cancer therapy

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Targeting cellular metabolism to improve cancer therapeutics

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Activating oxidative phosphorylation by a pyruvate dehydrogenase kinase inhibitor overcomes sorafenib resistance of hepatocellular carcinoma

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Phosphofructokinase type 1 kinetics, isoform expression, and gene polymorphisms in cancer cells

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29 September 2017

Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications

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Green tea polyphenol EGCG blunts androgen receptor function in prostate cancer

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29 September 2017

Regulation of mammalian muscle type 6-phosphofructo-1-kinase and its implication for the control of the metabolism

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29 September 2017

Heart 6-phosphofructo-2-kinase activation by insulin requires PKB (protein kinase B), but not SGK3 (serum- and glucocorticoid-induced protein kinase 3).

1 reference

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29 September 2017

Understanding the Warburg effect: the metabolic requirements of cell proliferation

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Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy

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29 September 2017

Acetylsalicylic acid and salicylic acid decrease tumor cell viability and glucose metabolism modulating 6-phosphofructo-1-kinase structure and activity

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29 September 2017

Phosphorylation of Bad at Thr-201 by JNK1 promotes glycolysis through activation of phosphofructokinase-1.

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29 September 2017

EGCG inhibits activation of the insulin-like growth factor (IGF)/IGF-1 receptor axis in human hepatocellular carcinoma cells

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Lactate favours the dissociation of skeletal muscle 6-phosphofructo-1-kinase tetramers down-regulating the enzyme and muscle glycolysis

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Regulation of tumor pH and the role of carbonic anhydrase 9.

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Hypoxia signalling controls metabolic demand

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29 September 2017

(-)-Epigallocatechin gallate and polyphenon E inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells

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Short-term administration of (-)-epigallocatechin gallate reduces hepatic steatosis and protects against warm hepatic ischemia/reperfusion injury in steatotic mice.

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On the Origin of Cancer Cells

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29 September 2017

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Inhibition of carcinogenesis by tea.

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29 September 2017

Tea polyphenols: prevention of cancer and optimizing health

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29 September 2017

Partial ATP depletion induces Fas- and caspase-mediated apoptosis in MDCK cells.

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29 September 2017

Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells

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29 September 2017

c-Myc transactivation of LDH-A: implications for tumor metabolism and growth

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29 September 2017

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

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Maximum activities of key enzymes of glycolysis, glutaminolysis, pentose phosphate pathway and tricarboxylic acid cycle in normal, neoplastic and suppressed cells

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29 September 2017

13 Phosphofructokinase from rabbit skeletal muscle

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29 September 2017

Subunit composition, regulatory properties, and phosphorylation of phosphofructokinase from human gliomas.

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27 June 2018

Factors affecting the activation of rabbit muscle phosphofructokinase by actin.

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27 June 2018

Improving the Anticancer Efficacy of Laminin Receptor-Specific Therapeutic Ruthenium Nanoparticles (RuBB-Loaded EGCG-RuNPs) via ROS-Dependent Apoptosis in SMMC-7721 Cells

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4 September 2018

In vitro and in vivo study of phloretin-induced apoptosis in human liver cancer cells involving inhibition of type II glucose transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4923908

4 September 2018

ATP and fructose-2,6-bisphosphate regulate skeletal muscle 6-phosphofructo-1-kinase by altering its quaternary structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4923908

4 September 2018

Fructose-2,6-bisphosphate counteracts guanidinium chloride-, thermal-, and ATP-induced dissociation of skeletal muscle key glycolytic enzyme 6-phosphofructo-1-kinase: A structural mechanism for PFK allosteric regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4923908

4 September 2018

Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: a metabolic survival role for tumor-associated stroma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4923908

4 September 2018

Involvement of proapoptotic Bcl-2 family members in terbinafine-induced mitochondrial dysfunction and apoptosis in HL60 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4923908

4 September 2018

Calcium influx: a possible role for insulin modulation of intracellular distribution and activity of 6-phosphofructo-1-kinase in human erythrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4923908

4 September 2018

VEGF receptors on chronic lymphocytic leukemia (CLL) B cells interact with STAT 1 and 3: implication for apoptosis resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4923908

4 September 2018

Oral consumption of green tea polyphenols inhibits insulin-like growth factor-I-induced signaling in an autochthonous mouse model of prostate cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4923908

4 September 2018

A radioassay for phosphofructokinase-1 activity in cell extracts and purified enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4923908

4 September 2018

p-Nitrophenylphosphatase activity catalyzed by plasma membrane (Ca(2+) + Mg(2+)ATPase: correlation with structural changes modulated by glycerol and Ca(2+).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4923908

4 September 2018

Why drinking green tea could prevent cancer

1 reference

https://api.crossref.org/works/10.1038%2FSREP28479

21 January 2018

Cell cycle dysregulation by green tea polyphenol epigallocatechin-3-gallate

1 reference

https://pubmed.ncbi.nlm.nih.gov/27349173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Akt Reverses the Acquired Resistance to Sorafenib by Switching Protective Autophagy to Autophagic Cell Death in Hepatocellular Carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/27349173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clotrimazole inhibits and modulates heterologous association of the key glycolytic enzyme 6-phosphofructo-1-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/27349173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Higher discontinuation and lower survival rates are likely in elderly Japanese patients with advanced hepatocellular carcinoma receiving sorafenib

1 reference

https://pubmed.ncbi.nlm.nih.gov/27349173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of 6-phosphofructo-1-kinase oligomeric equilibrium by calmodulin: formation of active dimers

1 reference

https://pubmed.ncbi.nlm.nih.gov/27349173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fructose 2,6-bisphosphate and the control of glycolysis by glucocorticoids and by other agents in rat hepatoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27349173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of tumor cell-derived lactic acid on human T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27349173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SREP28479

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27349173%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27349173%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27349173%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

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