(Q37048337)

English

Leucine-rich repeat and immunoglobulin domain-containing protein-1 (Lrig1) negative regulatory action toward ErbB receptor tyrosine kinases is opposed by leucine-rich repeat and immunoglobulin domain-containing protein 3 (Lrig3).

scientific article published on 30 May 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Leucine-rich repeat and immunoglobulin domain-containing protein-1 (Lrig1) negative regulatory action toward ErbB receptor tyrosine kinases is opposed by leucine-rich repeat and immunoglobulin domain-containing protein 3 (Lrig3). (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

author name string

Hanine Rafidi

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Francisco Mercado

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Michael Astudillo

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

William H D Fry

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Matthew Saldana

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Kermit L Carraway

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Colleen Sweeney

7

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

0 references

publication date

30 May 2013

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

288

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

30

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

21593-21605

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

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The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor

1 reference

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Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling

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Vertebrate Lrig3-ErbB interactions occur in vitro but are unlikely to play a role in Lrig3-dependent inner ear morphogenesis

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Suppression of the negative regulator LRIG1 contributes to ErbB2 overexpression in breast cancer

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LRIG1 negatively regulates the oncogenic EGF receptor mutant EGFRvIII.

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Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways

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LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy

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Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence

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Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

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Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity

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The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases

1 reference

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LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation

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LRIG1 and epidermal growth factor receptor in renal cell carcinoma: a quantitative RT--PCR and immunohistochemical analysis

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LRIG1 protein in human cells and tissues

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Is LRIG1 a tumour suppressor gene at chromosome 3p14.3?

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Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy

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Identifiers

10.1074/JBC.M113.486050

1 reference

https://api.fatcat.wiki/v0/release/fcfaoayckfgfnmznnckxvm2ama

30 July 2022

based on heuristic

mapped directly with Wikidata item

release_fcfaoayckfgfnmznnckxvm2ama

1 reference

https://api.fatcat.wiki/v0/release/fcfaoayckfgfnmznnckxvm2ama

30 July 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

https://api.fatcat.wiki/v0/release/fcfaoayckfgfnmznnckxvm2ama

30 July 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

https://api.fatcat.wiki/v0/release/fcfaoayckfgfnmznnckxvm2ama

30 July 2022

based on heuristic

mapped directly with Wikidata item

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