(Q37054538)

English

IL4 and IL-17A provide a Th2/Th17-polarized inflammatory milieu in favor of TGF-β1 to induce bronchial epithelial-mesenchymal transition (EMT).

scientific article published on 15 July 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

IL4 and IL-17A provide a Th2/Th17-polarized inflammatory milieu in favor of TGF-β1 to induce bronchial epithelial-mesenchymal transition (EMT). (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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14

object named as

Xudong Xiang

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Europe PubMed Central

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18 August 2017

9

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Subo Gong

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18 August 2017

1

object named as

Xiaoying Ji

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18 August 2017

author name string

Jinxiu Li

2

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18 August 2017

Li Xu

3

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18 August 2017

Wenjing Wang

4

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Europe PubMed Central

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18 August 2017

Ming Luo

5

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18 August 2017

Shuangling Luo

6

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Europe PubMed Central

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18 August 2017

Libing Ma

7

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Europe PubMed Central

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18 August 2017

Keng Li

8

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Europe PubMed Central

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18 August 2017

Long He

10

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18 August 2017

Zhijun Zhang

11

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Europe PubMed Central

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18 August 2017

Ping Yang

12

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18 August 2017

Zhiguang Zhou

13

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18 August 2017

Cong-Yi Wang

15

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18 August 2017

publication date

15 July 2013

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Europe PubMed Central

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18 August 2017

International Journal of Clinical and Experimental Pathology

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18 August 2017

6

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18 August 2017

8

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18 August 2017

1481-1492

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18 August 2017

Pediatric severe asthma is characterized by eosinophilia and remodeling without T(H)2 cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Airway epithelial cells from asthmatic children differentially express proremodeling factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Epithelial-mesenchymal-transition induced by EGFR activation interferes with cell migration and response to irradiation and cetuximab in head and neck cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

T(H)17 cells in asthma and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Chronic respiratory aeroallergen exposure in mice induces epithelial-mesenchymal transition in the large airways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Loss of Jak2 selectively suppresses DC-mediated innate immune response and protects mice from lethal dose of LPS-induced septic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Evidence for airway remodeling in chronic asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Biomarkers for epithelial-mesenchymal transitions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

TGF-beta1 induces human bronchial epithelial cell-to-mesenchymal transition in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Inflammatory and remodeling events in asthma with chronic exposure to house dust mites: a murine model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Transforming growth factor-beta induces epithelial to mesenchymal transition by down-regulation of claudin-1 expression and the fence function in adult rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Epithelial cell proliferation contributes to airway remodeling in severe asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Transforming growth factor beta: a central modulator of pulmonary and airway inflammation and fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Interleukin (IL)-4 and IL-13 up-regulate monocyte chemoattractant protein-1 expression in human bronchial epithelial cells: involvement of p38 mitogen-activated protein kinase, extracellular signal-regulated kinase 1/2 and Janus kinase-2 but not c-J

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Epithelial to mesenchymal transition in Madin-Darby canine kidney cells is accompanied by down-regulation of Smad3 expression, leading to resistance to transforming growth factor-beta-induced growth arrest.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Ultrastructural examination of bronchial biopsy specimens from children with moderate asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Consequences of long-term inflammation. Airway remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

29 September 2017

Loss of methyl-CpG-binding domain protein 2 enhances endothelial angiogenesis and protects mice against hind-limb ischemic injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

27 June 2018

House dust mite-promoted epithelial-to-mesenchymal transition in human bronchial epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

27 June 2018

Apoptosis and loss of adhesion of bronchial epithelial cells in asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

27 June 2018

Loss of dicer exacerbates cyclophosphamide-induced bladder overactivity by enhancing purinergic signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

4 September 2018

Interleukin-17A induces glucocorticoid insensitivity in human bronchial epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

4 September 2018

Transition of asthmatic bronchial fibroblasts to myofibroblasts is inhibited by cell-cell contacts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

4 September 2018

Differential susceptibility to epithelial-mesenchymal transition (EMT) of alveolar, bronchial and intestinal epithelial cells in vitro and the effect of angiotensin II receptor inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

4 September 2018

The overexpression of heparin-binding epidermal growth factor is responsible for Th17-induced airway remodeling in an experimental asthma model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

4 September 2018

Th17 immunity in patients with allergic asthma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

4 September 2018

Induction of epithelial-mesenchymal transition in primary airway epithelial cells from patients with asthma by transforming growth factor-beta1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

4 September 2018

Transcription factors T-bet and GATA-3 regulate development of airway remodeling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

4 September 2018

Altered protein tyrosine phosphorylation in asthmatic bronchial epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

4 September 2018

Induction of an epithelial to mesenchymal transition in human immortal and malignant keratinocytes by TGF-beta1 involves MAPK, Smad and AP-1 signalling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

4 September 2018

Increased interleukin-4, interleukin-5, and interferon-gamma in airway CD4+ and CD8+ T cells in atopic asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

4 September 2018

Type 2 cytokines in the pathogenesis of sustained airway dysfunction and airway remodeling in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

4 September 2018

Proliferation and inflammation in bronchial epithelium after allergen in atopic asthmatics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

4 September 2018

IL-17A promotes the growth of airway epithelial cells through ERK-dependent signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726963

4 December 2018

Early thickening of the reticular basement membrane in children with difficult asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23923066

12 December 2020

based on heuristic

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Central role for Rho in TGF-beta1-induced alpha-smooth muscle actin expression during epithelial-mesenchymal transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/23923066

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated T cells and cytokines in bronchoalveolar lavages from patients with various lung diseases associated with eosinophilia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23923066

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta 1 in asthma. Measurement in bronchoalveolar lavage fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/23923066

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Der p, IL-4, and TGF-beta cooperatively induce EGFR-dependent TARC expression in airway epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/23923066

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-beta suppresses EGF-induced MAPK signaling and proliferation in asthmatic epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23923066

12 December 2020

based on heuristic

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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