(Q37059658)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18202699%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

review article

1 reference

title

Turn me on: regulating HIF transcriptional activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18202699%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18202699%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

author name string

K Lisy

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18202699%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

publication date

18 January 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18202699%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

1 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18202699%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18202699%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18202699%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

page(s)

642-649

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18202699%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4402315

1 January 2020

exact match

0 references

cites work

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The hypoxia-inducible factors: key transcriptional regulators of hypoxic responses.

21 January 2018

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Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression

21 January 2018

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Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible splicing variant of the hypoxia-inducible factor-3alpha locus

21 January 2018

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Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

21 January 2018

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RACK1 vs. HSP90: competition for HIF-1 alpha degradation vs. stabilization

21 January 2018

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Novel DNA binding by a basic helix-loop-helix protein. The role of the dioxin receptor PAS domain

21 January 2018

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A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

21 January 2018

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Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide

21 January 2018

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Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways

21 January 2018

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Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension

21 January 2018

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The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha

21 January 2018

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An essential role for p300/CBP in the cellular response to hypoxia

21 January 2018

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Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

21 January 2018

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Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

21 January 2018

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Recruitment of thyroid hormone receptor/retinoblastoma-interacting protein 230 by the aryl hydrocarbon receptor nuclear translocator is required for the transcriptional response to both dioxin and hypoxia

21 January 2018

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The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha

21 January 2018

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Oxygen-regulated and transactivating domains in endothelial PAS protein 1: comparison with hypoxia-inducible factor-1alpha.

21 January 2018

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FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

21 January 2018

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FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

21 January 2018

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Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

21 January 2018

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The role of iron and 2-oxoglutarate oxygenases in signalling

21 January 2018

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Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases

21 January 2018

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Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

21 January 2018

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Signalling hypoxia by HIF hydroxylases

21 January 2018

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Regulating cellular oxygen sensing by hydroxylation.

21 January 2018

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Mitochondrial oxygen sensing: regulation of hypoxia-inducible factor by mitochondrial generated reactive oxygen species

21 January 2018

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Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].

21 January 2018

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Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay

21 January 2018

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Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response

21 January 2018

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Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha

21 January 2018

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Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha

21 January 2018

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Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor

21 January 2018

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Modulation of p300 binding by posttranslational modifications of the C-terminal activation domain of hypoxia-inducible factor-1alpha

21 January 2018

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Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissues.

21 January 2018

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Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

21 January 2018

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Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

21 January 2018

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Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor

21 January 2018

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ASB4 is a hydroxylation substrate of FIH and promotes vascular differentiation via an oxygen-dependent mechanism

21 January 2018

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Siah-1 facilitates ubiquitination and degradation of factor inhibiting HIF-1alpha (FIH).

21 January 2018

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Protein kinase C-mediated modulation of FIH-1 expression by the homeodomain protein CDP/Cut/Cux

21 January 2018

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The length of peptide substrates has a marked effect on hydroxylation by the hypoxia-inducible factor prolyl 4-hydroxylases

21 January 2018

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Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates

21 January 2018

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The transcriptional activation function of the HIF-like factor requires phosphorylation at a conserved threonine

21 January 2018

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Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity

21 January 2018

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MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300

21 January 2018

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Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1alpha.

21 January 2018

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S-nitrosation of Cys-800 of HIF-1alpha protein activates its interaction with p300 and stimulates its transcriptional activity

21 January 2018

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RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402315

Sumoylation increases HIF-1alpha stability and its transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402315

SUMOylation of hypoxia-inducible factor-1alpha reduces its transcriptional activity.

21 January 2018

1 reference

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SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402315

Activity of hypoxia-inducible factor 2alpha is regulated by association with the NF-kappaB essential modulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402315

Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha ) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1)

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4402315

Human hypoxic signal transduction through a signature motif in hepatocyte nuclear factor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402315

Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression

21 January 2018

1 reference

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HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402315

Hypoxia requires notch signaling to maintain the undifferentiated cell state

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402315

Interaction of the PAS B domain with HSP90 accelerates hypoxia-inducible factor-1alpha stabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402315

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402315

7 January 2021

Hypoxia rapidly activates HIF-3alpha mRNA expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402315

7 January 2021

Mechanical loading regulates expression of talin and its mRNA, which are concentrated at myotendinous junctions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402315

7 January 2021

Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402315

7 January 2021

Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402315

7 January 2021

Cell-specific regulation of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha stabilization and transactivation in a graded oxygen environment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402315

7 January 2021

Transitional change in interaction between HIF-1 and HNF-4 in response to hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402315

7 January 2021