(Q37072116)

English

Specific interactions between the viral coreceptor CXCR4 and the biguanide-based compound NB325 mediate inhibition of human immunodeficiency virus type 1 infection

scientific article published on December 2008

In more languages

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Specific interactions between the viral coreceptor CXCR4 and the biguanide-based compound NB325 mediate inhibition of human immunodeficiency virus type 1 infection (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

author name string

Nina Thakkar

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Vanessa Pirrone

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Shendra Passic

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Wei Zhu

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Vladyslav Kholodovych

5

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

William Welsh

6

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Robert F Rando

7

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Mohamed E Labib

8

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Brian Wigdahl

9

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Fred C Krebs

10

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

0 references

publication date

1 December 2008

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

53

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

631-638

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

An update in the development of HIV entry inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

HIV entry inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

Microbicide drug candidates to prevent HIV infection

1 reference

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29 September 2017

HIV co-receptor inhibitors as novel class of anti-HIV drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

Microbicides and other topical strategies to prevent vaginal transmission of HIV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

Distinct functional sites for human immunodeficiency virus type 1 and stromal cell-derived factor 1alpha on CXCR4 transmembrane helical domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

Anti-CXCR4 monoclonal antibodies recognizing overlapping epitopes differ significantly in their ability to inhibit entry of human immunodeficiency virus type 1.

1 reference

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29 September 2017

Anti-HIV activity and conformational studies of peptides derived from the C-terminal sequence of SDF-1.

1 reference

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29 September 2017

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

1 reference

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29 September 2017

Structural and functional characterization of human CXCR4 as a chemokine receptor and HIV-1 co-receptor by mutagenesis and molecular modeling studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

Pharmacological evidence for complex and multiple site interaction of CXCR4 with SDF-1alpha: implications for development of selective CXCR4 antagonists

1 reference

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29 September 2017

The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivity

1 reference

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29 September 2017

A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5

1 reference

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29 September 2017

International union of pharmacology. XXII. Nomenclature for chemokine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

HIV-1 envelope induces activation of caspase-3 and cleavage of focal adhesion kinase in primary human CD4(+) T cells

1 reference

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29 September 2017

Vaginal disinfection with chlorhexidine during childbirth

1 reference

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29 September 2017

Mutagenesis of CXCR4 identifies important domains for human immunodeficiency virus type 1 X4 isolate envelope-mediated membrane fusion and virus entry and reveals cryptic coreceptor activity for R5 isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

T cell-tropic HIV gp120 mediates CD4 and CD8 cell chemotaxis through CXCR4 independent of CD4: implications for HIV pathogenesis

1 reference

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29 September 2017

0.25% chlorhexidine gluconate gel. A protective topical microbicide

1 reference

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29 September 2017

The second extracellular loop of CXCR4 is involved in CD4-independent entry of human immunodeficiency virus type 2.

1 reference

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29 September 2017

Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

Role of the first and third extracellular domains of CXCR-4 in human immunodeficiency virus coreceptor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

CD4-independent infection by HIV-2 (ROD/B): use of the 7-transmembrane receptors CXCR-4, CCR-3, and V28 for entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

Role of the amino-terminal extracellular domain of CXCR-4 in human immunodeficiency virus type 1 entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

CD4-independent association between HIV-1 gp120 and CXCR4: functional chemokine receptors are expressed in human neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

29 September 2017

Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes

1 reference

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29 September 2017

A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

1 reference

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29 September 2017

Inhibition of gp160 and CD4 maturation in U937 cells after both defective and productive infections by human immunodeficiency virus type 1.

1 reference

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29 September 2017

Separation of functional subsets of human T cells by a monoclonal antibody

1 reference

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Maraviroc: integration of a new antiretroviral drug class into clinical practice

1 reference

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Marked structural and functional heterogeneity in CXCR4: separation of HIV-1 and SDF-1alpha responses

1 reference

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27 June 2018

Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: rapid internalization and recycling upon activation.

1 reference

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27 June 2018

CD4-independent infection by HIV-2 is mediated by fusin/CXCR4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

27 June 2018

Effects of chlorhexidine gluconate douche on normal vaginal flora

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

27 June 2018

Polybiguanides, particularly polyethylene hexamethylene biguanide, have activity against human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

4 September 2018

Impact of antimicrobial gauze on bacterial colonies in wounds that require packing.

1 reference

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4 September 2018

In vitro efficacy of a polyhexamethylene biguanide-impregnated gauze dressing against bacteria found in veterinary patients.

1 reference

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4 September 2018

Effect of a polyhexamethylene biguanide mouthrinse on bacterial counts and plaque

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630669

4 September 2018

Entry of R5X4 and X4 human immunodeficiency virus type 1 strains is mediated by negatively charged and tyrosine residues in the amino-terminal domain and the second extracellular loop of CXCR4.

1 reference

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4 September 2018

Stromal cell-derived factor-1alpha associates with heparan sulfates through the first beta-strand of the chemokine.

1 reference

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4 September 2018

In vitro and in vivo effects of polyhexamethylene biguanide against herpes simplex virus infection.

1 reference

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4 September 2018

G protein-coupled chemokine receptors induce both survival and apoptotic signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Propidium iodide as a nuclear counterstain for immunofluorescence studies on cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of Acanthamoeba keratitis with polyhexamethylene biguanide

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047650

12 December 2020

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inferred from PubMed ID database lookup

Evaluating the preservative effectiveness of RGP lens care solutions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047650

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Mapping the binding of the N-terminal extracellular tail of the CXCR4 receptor to stromal cell-derived factor-1alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.00866-08

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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