(Q37076763)

18 August 2017

Preclinical evaluation of a novel ATM inhibitor, KU59403, in vitro and in vivo in p53 functional and dysfunctional models of human cancer (English)

1 reference

18 August 2017

Michael A Batey

1

1 reference

18 August 2017

Yan Zhao

2

1 reference

18 August 2017

Suzanne Kyle

3

1 reference

18 August 2017

Caroline Richardson

4

1 reference

18 August 2017

Andrew Slade

5

1 reference

18 August 2017

Niall M B Martin

6

1 reference

18 August 2017

Alan Lau

7

1 reference

18 August 2017

David R Newell

8

1 reference

18 August 2017

Nicola J Curtin

9

1 reference

18 August 2017

language of work or name

1 reference

19 March 2013

1 reference

Molecular Cancer Therapeutics

18 August 2017

1 reference

18 August 2017

12

1 reference

18 August 2017

6

1 reference

18 August 2017

959-967

1 reference

Guidelines for the welfare and use of animals in cancer research

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

Cell-cycle checkpoints and cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

G1 cell-cycle control and cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

Ataxia-telangiectasia, an evolving phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

ATM as a target for novel radiosensitizers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

Cooperation between p53 and hMLH1 in a human colocarcinoma cell line in response to DNA damage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

The ATM-mediated DNA-damage response: taking shape.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

Disruption of the ATM gene in breast cancer.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736091

The role of DNA single- and double-strand breaks in cell killing by ionizing radiation

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23512991

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Loss of atm radiosensitizes multiple p53 null tissues

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23512991

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Competitive and noncompetitive inhibition of the DNA-dependent protein kinase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23512991

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1535-7163.MCT-12-0707

1 reference

18 August 2017

1 reference

18 August 2017

PubMed publication ID

23512991

1 reference