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Use of the Rad51 promoter for targeted anti-cancer therapy
scholarly article
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
2634908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19106292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
title
Use of the Rad51 promoter for targeted anti-cancer therapy
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2634908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19106292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
author
Christopher Hine
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2634908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19106292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
Vera Gorbunova
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
2634908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19106292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
author name string
Andrei Seluanov
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
2634908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19106292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
language of work or name
English
0 references
publication date
23 December 2008
1 reference
stated in
Europe PubMed Central
PMCID
2634908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19106292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
Europe PubMed Central
PMCID
2634908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19106292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
volume
105
1 reference
stated in
Europe PubMed Central
PMCID
2634908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19106292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
issue
52
1 reference
stated in
Europe PubMed Central
PMCID
2634908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19106292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
page(s)
20810-20815
1 reference
stated in
Europe PubMed Central
PMCID
2634908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19106292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
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Rad51 overexpression contributes to chemoresistance in human soft tissue sarcoma cells: a role for p53/activator protein 2 transcriptional regulation
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Characterisation of the promoter region of the human DNA-repair gene Rad51
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p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene
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29 September 2017
High-level expression of Rad51 is an independent prognostic marker of survival in non-small-cell lung cancer patients
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PubMed Central
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29 September 2017
The RAD51 gene family, genetic instability and cancer
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PubMed Central
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29 September 2017
RAD51, genomic stability, and tumorigenesis
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Midkine promoter-driven suicide gene expression and -mediated adenovirus replication produced cytotoxic effects to immortalised and tumour cells
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Gleevec-mediated inhibition of Rad51 expression and enhancement of tumor cell radiosensitivity
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Transcriptionally targeted gene therapy to detect and treat cancer
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29 September 2017
Telomerase promoter-driven cancer gene therapy
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PubMed Central
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29 September 2017
p53 interacts with hRAD51 and hRAD54, and directly modulates homologous recombination
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Fusion tyrosine kinases induce drug resistance by stimulation of homology-dependent recombination repair, prolongation of G(2)/M phase, and protection from apoptosis
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BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance
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The telomerase reverse transcriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters
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29 September 2017
Ribozyme minigene-mediated RAD51 down-regulation increases radiosensitivity of human prostate cancer cells
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29 September 2017
RAD51 supports spontaneous non-homologous recombination in mammalian cells, but not the corresponding process induced by topoisomerase inhibitors
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29 September 2017
Over-expression of wild-type Rad51 correlates with histological grading of invasive ductal breast cancer
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29 September 2017
DNA repair and recombination factor Rad51 is over-expressed in human pancreatic adenocarcinoma
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PubMed Central
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29 September 2017
In vitro and in vivo potentiation of radiosensitivity of malignant gliomas by antisense inhibition of the RAD51 gene
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PubMed Central
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29 September 2017
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29 September 2017
Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro
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PubMed Central
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29 September 2017
Role of the human RAD51 protein in homologous recombination and double-stranded-break repair.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634908
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Internucleosomal DNA cleavage precedes diphtheria toxin-induced cytolysis. Evidence that cell lysis is not a simple consequence of translation inhibition
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634908
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27 June 2018
In vivo imaging of lymph node metastasis with telomerase-specific replication-selective adenovirus
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634908
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3 September 2018
Cancer-specific activation of the survivin promoter and its potential use in gene therapy
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634908
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3 September 2018
Rad51 overexpression promotes alternative double-strand break repair pathways and genome instability
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634908
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3 September 2018
Direct interstitial infusion of NK1-targeted neurotoxin into the spinal cord: a computational model.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634908
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3 September 2018
Tumor-specific activation of hTERT-derived promoters by tumor suppressive E1A-mutants involves recruitment of p300/CBP/HAT and suppression of HDAC-1 and defines a combined tumor targeting and suppression system
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634908
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3 September 2018
Novel oncolytic adenoviruses targeted to melanoma: specific viral replication and cytolysis by expression of E1A mutants from the tyrosinase enhancer/promoter
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634908
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3 September 2018
Treatment of malignant glioma cells with the transfer of constitutively active caspase-6 using the human telomerase catalytic subunit (human telomerase reverse transcriptase) gene promoter.
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PubMed Central
reference URL
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3 September 2018
Tumor-specific transgene expression from the human telomerase reverse transcriptase promoter enables targeting of the therapeutic effects of the Bax gene to cancers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634908
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3 September 2018
A novel telomerase-specific gene therapy: gene transfer of caspase-8 utilizing the human telomerase catalytic subunit gene promoter
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634908
retrieved
3 September 2018
A telomerase-dependent conditionally replicating adenovirus for selective treatment of cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19106292
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19106292
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19106292
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19106292
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Characterization of the human Rad51 genomic locus and examination of tumors with 15q14-15 loss of heterozygosity (LOH)
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19106292
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.0807990106
1 reference
stated in
Europe PubMed Central
PMCID
2634908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19106292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
ADS bibcode
2008PNAS..10520810H
0 references
PMCID
2634908
1 reference
stated in
Europe PubMed Central
PMCID
2634908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19106292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
PubMed ID
19106292
1 reference
stated in
Europe PubMed Central
PMCID
2634908
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19106292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 January 2020
ResearchGate publication ID
23687971
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