(Q40810330)

English

The telomerase reverse transcriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters

scientific article published on April 2001

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scholarly article

1 reference

Europe PubMed Central

23 September 2017

The telomerase reverse transcriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters (English)

1 reference

Europe PubMed Central

23 September 2017

suicide prevention

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inferred from title

author name string

Majumdar AS

1

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Europe PubMed Central

23 September 2017

Hughes DE

2

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Europe PubMed Central

23 September 2017

Lichtsteiner SP

3

1 reference

Europe PubMed Central

23 September 2017

Wang Z

4

1 reference

Europe PubMed Central

23 September 2017

Lebkowski JS

5

1 reference

Europe PubMed Central

23 September 2017

Vasserot AP

6

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Europe PubMed Central

23 September 2017

publication date

1 April 2001

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Europe PubMed Central

23 September 2017

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Europe PubMed Central

23 September 2017

8

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Europe PubMed Central

23 September 2017

568-578

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Europe PubMed Central

23 September 2017

7

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Europe PubMed Central

23 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.gt.3301421

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Molecular chemotherapy for breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Progress in transcriptionally targeted and regulatable vectors for genetic therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Telomerase catalytic subunit homologs from fission yeast and human

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Differentiation of immortal cells inhibits telomerase activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Down-regulation of telomerase activity is an early event of cellular differentiation without apparent telomeric DNA change.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Suppression of telomerase reverse transcriptase (hTERT) expression in differentiated HL-60 cells: regulatory mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Expression of TERT in early premalignant lesions and a subset of cells in normal tissues.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Immuno-histochemical detection of human telomerase catalytic component, hTERT, in human colorectal tumor and non-tumor tissue sections.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

The serial cultivation of human diploid cell strains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Telomeres shorten during ageing of human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Telomere loss: mitotic clock or genetic time bomb?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Specific association of human telomerase activity with immortal cells and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

A survey of telomerase activity in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

The RNA component of human telomerase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Induction of hTERT expression and telomerase activity by estrogens in human ovary epithelium cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Direct activation of TERT transcription by c-MYC.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

In vivo and in vitro analyses of Myc for differential promoter activities of the human telomerase (hTERT) gene in normal and tumor cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Gene therapy for lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Changes in gene expression and targets for therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Gene therapy: designer promoters for tumour targeting

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Low levels of herpes simplex virus thymidine- thymidylate kinase are not limiting for sensitivity to certain antiviral drugs or for latency in a mouse model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Gene therapy of experimental malignant mesothelioma using adenovirus vectors encoding the HSVtk gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Efficacy of herpes simplex virus thymidine kinase in combination with cytokine gene therapy in an experimental metastatic breast cancer model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

21 January 2018

Telomerase is active in normal gastrointestinal mucosa and not up-regulated in precancerous lesions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantitative reevaluation of telomerase activity in cancerous and noncancerous gastrointestinal tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

7 January 2021

based on heuristic

inferred from DOI database lookup

Telomerase activity concentrates in the mitotically active segments of human hair follicles

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

7 January 2021

based on heuristic

inferred from DOI database lookup

Antiviral activity and mechanism of action of ganciclovir

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

7 January 2021

based on heuristic

inferred from DOI database lookup

The Wilms' tumor 1 tumor suppressor gene represses transcription of the human telomerase reverse transcriptase gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301421

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.GT.3301421

1 reference

Europe PubMed Central

23 September 2017

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1 reference

Europe PubMed Central

23 September 2017

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