(Q37082951)

18 August 2017

1 reference

title

The role of IGF-I and its binding proteins in the development of type 2 diabetes and cardiovascular disease (English)

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18 August 2017

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cardiovascular disease

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3

Stephen B Wheatcroft

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18 August 2017

4

Mark T Kearney

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18 August 2017

1

Vivienne A Ezzat

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18 August 2017

Edward R Duncan

2

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18 August 2017

language of work or name

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1 March 2008

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Diabetes, Obesity and Metabolism

18 August 2017

published in

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18 August 2017

volume

10

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18 August 2017

issue

3

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18 August 2017

page(s)

198-211

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Determinants of atherosclerosis in the young. Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group.

18 August 2017

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21 January 2018

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21 January 2018

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Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

21 January 2018

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IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms

21 January 2018

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Cellular actions of the insulin-like growth factor binding proteins

21 January 2018

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21 January 2018

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Reduced levels of insulin-like growth factor-1 in patients with angina pectoris, positive exercise stress test, and angiographically normal epicardial coronary arteries.

21 January 2018

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Insulin-like growth factor-I and insulin-like growth factor binding protein-1 in a representative population of type 2 diabetic patients in Sweden.

21 January 2018

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C-reactive protein and the insulin-like growth factor (IGF)-system in relation to risk of cardiovascular disease in different ethnic groups

21 January 2018

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21 January 2018

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Close relation of fasting insulin-like growth factor binding protein-1 (IGFBP-1) with glucose tolerance and cardiovascular risk in two populations.

21 January 2018

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Circulating insulin-like growth factor-I levels are correlated with the atherosclerotic profile in healthy subjects independently of age.

21 January 2018

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Markedly reduced insulin-like growth factor-1 in the acute phase of myocardial infarction

21 January 2018

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Growth hormone and insulin-like growth factor-1 in acute myocardial infarction.

21 January 2018

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Low serum insulin-like growth factor I is associated with increased risk of ischemic heart disease: a population-based case-control study

21 January 2018

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The prospective association of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-1 levels with all cause and cardiovascular disease mortality in older adults: the Rancho Bernardo Study

21 January 2018

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Serum total IGF-I, free IGF-I, and IGFB-1 levels in an elderly population: relation to cardiovascular risk factors and disease.

21 January 2018

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A polymorphism in the gene for IGF-I: functional properties and risk for type 2 diabetes and myocardial infarction

21 January 2018

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Endogenous hormones and carotid atherosclerosis in elderly men.

21 January 2018

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Low circulating levels of insulin-like growth factor binding protein-1 (IGFBP-1) are closely associated with the presence of macrovascular disease and hypertension in type 2 diabetes.

21 January 2018

1 reference

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Inhibition of vascular smooth muscle cell growth through antisense transcription of a rat insulin-like growth factor I receptor cDNA.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

IGF-1 and macrovascular complications of diabetes: alternative interpretations of recently published data

21 January 2018

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Defect in insulin-like growth factor-1 survival mechanism in atherosclerotic plaque-derived vascular smooth muscle cells is mediated by reduced surface binding and signaling

21 January 2018

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Liver-derived insulin-like growth factor-I is involved in the regulation of blood pressure in mice

21 January 2018

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Atherosclerosis — An Inflammatory Disease

21 January 2018

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Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide

21 January 2018

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Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

21 January 2018

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Nitric oxide: an endogenous modulator of leukocyte adhesion

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

An L-arginine/nitric oxide pathway present in human platelets regulates aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Recombinant human insulin-like growth factor-I increases forearm blood flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Direct demonstration of insulin-like growth factor-I-induced nitric oxide production by endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Expression, regulation, and function of IGF-1, IGF-1R, and IGF-1 binding proteins in blood vessels

21 January 2018

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Impaired insulin-like growth factor I vasorelaxant effects in hypertension.

21 January 2018

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The somatomedin hypothesis: 2001.

21 January 2018

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Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

21 January 2018

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Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

21 January 2018

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Evidence that IRS-2 phosphorylation is required for insulin action in hepatocytes.

21 January 2018

1 reference

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Signaling via the insulin-like growth factor-I receptor: does it differ from insulin receptor signaling?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Signalling through IGF-I and insulin receptors: where is the specificity?

21 January 2018

1 reference

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Differential roles of the insulin and insulin-like growth factor-I (IGF-I) receptors in response to insulin and IGF-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Insulin-like growth factor-1 improves postischemic recovery in hypertrophied hearts

21 January 2018

1 reference

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Cardioprotective effect of insulin-like growth factor I in myocardial ischemia followed by reperfusion

21 January 2018

1 reference

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Insulin-like growth factor-1 but not growth hormone augments mammalian myocardial contractility by sensitizing the myofilament to Ca2+ through a wortmannin-sensitive pathway: studies in rat and ferret isolated muscles

21 January 2018

1 reference

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Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: a prospective observational study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Estradiol decreases IGF-1 and IGF-1 receptor expression in rat aortic smooth muscle cells. Mechanisms for its atheroprotective effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Anthropometric and behavioral correlates of insulin-like growth factor I and insulin-like growth factor binding protein 3 in middle-aged Japanese men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Sedentary life impairs self-reparative processes in the brain: the role of serum insulin-like growth factor-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

IGF-I in a normal population: relation to psychosocial factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

A potential inverse association between insulin-like growth factor I and hypertension in a cross-sectional study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Serum insulin-like growth factor-I level is independently associated with coronary artery disease progression in young male survivors of myocardial infarction: beneficial effects of bezafibrate treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

The impact of abnormalities in IGF and inflammatory systems on the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Free insulin-like growth factors -- measurements and relationships to growth hormone secretion and glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Rh/IGF-I/rhIGFBP-3 administration to patients with type 2 diabetes mellitus reduces insulin requirements while also lowering fasting glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Recombinant human insulin-like growth factor-I therapy improves glycemic control and insulin action in the type A syndrome of severe insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

The combination of insulin-like growth factor I and insulin-like growth factor-binding protein-3 reduces insulin requirements in insulin-dependent type 1 diabetes: evidence for in vivo biological activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Randomised placebo-controlled trial of human recombinant insulin-like growth factor I plus intensive insulin therapy in adolescents with insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

IGF-I treatment in adults with type 1 diabetes: effects on glucose and protein metabolism in the fasting state and during a hyperinsulinemic-euglycemic amino acid clamp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Insulin-like growth factors and pancreas beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Pancreatic-specific inactivation of IGF-I gene causes enlarged pancreatic islets and significant resistance to diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Direct functional interactions between insulin-like growth factor-binding protein-3 and retinoid X receptor-alpha regulate transcriptional signaling and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Insulin-like growth factor-binding protein 1 stimulates human trophoblast migration by signaling through alpha 5 beta 1 integrin via mitogen-activated protein Kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Vascular endothelial function and blood pressure homeostasis in mice overexpressing IGF binding protein-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Massive hepatic apoptosis associated with TGF-beta1 activation after Fas ligand treatment of IGF binding protein-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Phosphorylation of insulin-like growth factor (IGF)-binding protein 1 in cell culture and in vivo: effects on affinity for IGF-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Dysregulation of the insulin/IGF binding protein-1 axis in transgenic mice is associated with hyperinsulinemia and glucose intolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Physiological differences in insulin-like growth factor binding protein-1 (IGFBP-1) phosphorylation in IGFBP-1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Insights from insulin-like growth factor binding protein transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Enhancement of insulin-like growth factor I activity by novel antisera: potential structure/function interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Treatment of type A insulin resistance with insulin-like growth factor-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

The insulin-like growth factor system and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Insulin-like growth factor-I treatment of growth disorders, diabetes mellitus and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Randomized double-blind Scandinavian trial of angiopeptin versus placebo for the prevention of clinical events and restenosis after coronary balloon angioplasty.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Effects of octreotide treatment on restenosis after coronary angioplasty: results of the VERAS study. VErringerung der Restenoserate nach Angioplastie durch ein Somatostatin-analogon

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Insulin-like growth factor I and II preserve myocardial structure in postinfarct swine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Insulin-like growth factor-1 exerts Ca2+-dependent positive inotropic effects in failing human myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Strategic advantages of insulin-like growth factor-I expression for cardioprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Cardiovascular risk factors in confirmed prediabetic individuals. Does the clock for coronary heart disease start ticking before the onset of clinical diabetes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Positive association between circulating free insulin-like growth factor–1 levels and coronary flow reserve in arterial systemic hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Decreased Expression of Insulin-like Growth Factor-1 and Apoptosis of Vascular Smooth Muscle Cells in Human Atherosclerotic Plaque

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

Effects of Recombinant Human IGF-I/IGF-Binding Protein-3 Complex on Glucose and Glycerol Metabolism in Type 1 Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2007.00709.X

10.1111/J.1463-1326.2007.00709.X

21 January 2018

Identifiers

DOI

1 reference

18 August 2017

1 reference