(Q37101211)

18 August 2017

1 reference

title

Mechanisms of disease: ion channel remodeling in the failing ventricle (English)

1 reference

18 August 2017

Robert D Nass

1

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18 August 2017

Takeshi Aiba

series ordinal

2

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18 August 2017

Gordon F Tomaselli

series ordinal

3

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18 August 2017

Fadi G Akar

series ordinal

4

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18 August 2017

publication date

4 March 2008

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Nature Clinical Practice Cardiovascular Medicine

18 August 2017

published in

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18 August 2017

volume

5

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18 August 2017

issue

4

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18 August 2017

page(s)

196-207

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Prevalence and mortality rate of congestive heart failure in the United States

18 August 2017

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7 January 2021

Ionic remodeling in the heart: pathophysiological significance and new therapeutic opportunities for atrial fibrillation

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7 January 2021

Mechanisms underlying conduction slowing and arrhythmogenesis in nonischemic dilated cardiomyopathy

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7 January 2021

IKs blockade reduces dispersion of repolarization in heart failure

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7 January 2021

Role of the calcium-independent transient outward current I(to1) in shaping action potential morphology and duration

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7 January 2021

K+ channels and control of ventricular repolarization in the heart

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7 January 2021

Molecular basis of transient outward potassium current downregulation in human heart failure: a decrease in Kv4.3 mRNA correlates with a reduction in current density

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7 January 2021

Molecular basis of transient outward K+ current diversity in mouse ventricular myocytes.

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7 January 2021

Phenotypic differences in transient outward K+ current of human and canine ventricular myocytes: insights into molecular composition of ventricular Ito.

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7 January 2021

Molecular mechanisms underlying K+ current downregulation in canine tachycardia-induced heart failure.

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7 January 2021

In vivo cardiac gene transfer of Kv4.3 abrogates the hypertrophic response in rats after aortic stenosis

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7 January 2021

Properties, expression and potential roles of cardiac K+ channel accessory subunits: MinK, MiRPs, KChIP, and KChAP.

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7 January 2021

Molecular physiology and modulation of somatodendritic A-type potassium channels

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7 January 2021

Modulation of A-type potassium channels by a family of calcium sensors

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7 January 2021

Regulation of KChIP2 potassium channel beta subunit gene expression underlies the gradient of transient outward current in canine and human ventricle

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7 January 2021

The MinK-related peptides

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7 January 2021

Differential distribution of inward rectifier potassium channel transcripts in human atrium versus ventricle

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7 January 2021

Biological pacemaker created by gene transfer

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7 January 2021

Blockade of the inward rectifying potassium current terminates ventricular fibrillation in the guinea pig heart

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7 January 2021

Up-regulation of the inward rectifier K+ current (I K1) in the mouse heart accelerates and stabilizes rotors

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7 January 2021

Acquired delayed rectifier channelopathies: how heart disease and antiarrhythmic drugs mimic potentially-lethal congenital cardiac disorders

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7 January 2021

Transmural action potential and ionic current remodeling in ventricles of failing canine hearts

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7 January 2021

Potassium channel subunit remodeling in rabbits exposed to long-term bradycardia or tachycardia: discrete arrhythmogenic consequences related to differential delayed-rectifier changes

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7 January 2021

Ionic remodeling of cardiac Purkinje cells by congestive heart failure

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7 January 2021

Unique topographical distribution of M cells underlies reentrant mechanism of torsade de pointes in the long-QT syndrome

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7 January 2021

KvLQT1 modulates the distribution and biophysical properties of HERG. A novel alpha-subunit interaction between delayed rectifier currents

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7 January 2021

Overexpression of a human potassium channel suppresses cardiac hyperexcitability in rabbit ventricular myocytes

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7 January 2021

Differences in the effect of metabolic inhibition on action potentials and calcium currents in endocardial and epicardial cells

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7 January 2021

Myocardial K(ATP) channels in preconditioning

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7 January 2021

The mitochondrial origin of postischemic arrhythmias

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7 January 2021

Mitochondrial criticality: a new concept at the turning point of life or death.

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7 January 2021

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

1 reference

7 January 2021

Characterization of the hyperpolarization-activated current, I(f), in ventricular myocytes from human failing heart

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Hyperpolarization-activated inward current in ventricular myocytes from normal and failing human hearts

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Occurrence and properties of the hyperpolarization-activated current If in ventricular myocytes from normotensive and hypertensive rats during aging

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

A family of hyperpolarization-activated mammalian cation channels

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Sinus node dysfunction and hyperpolarization-activated (HCN) channel subunit remodeling in a canine heart failure model

1 reference

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7 January 2021

Bioartificial sinus node constructed via in vivo gene transfer of an engineered pacemaker HCN Channel reduces the dependence on electronic pacemaker in a sick-sinus syndrome model

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7 January 2021

Heart rate slowing for myocardial dysfunction/heart failure

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7 January 2021

The electrophysiological characteristics of hypertrophied ventricular myocytes from the spontaneously hypertensive rat

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Ionic basis of action potential prolongation of hypertrophied cardiac myocytes isolated from hypertensive rats of different ages

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7 January 2021

Ca2+ currents in compensated hypertrophy and heart failure.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Electrical Remodeling in Cardiac Hypertrophy

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7 January 2021

Calcium currents in diseased human cardiac cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Membrane current changes in left ventricular myocytes isolated from guinea pigs after abdominal aortic coarctation

1 reference

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7 January 2021

Increased availability and open probability of single L-type calcium channels from failing compared with nonfailing human ventricle

1 reference

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7 January 2021

A critical role for L-type Ca2+ current in the regulation of Ca2+ release from the sarcoplasmic reticulum in human ventricular myocytes from dilated cardiomyopathy

1 reference

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7 January 2021

Gene therapy to inhibit the calcium channel beta subunit: physiological consequences and pathophysiological effects in models of cardiac hypertrophy

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7 January 2021

A mechanism of transition from ventricular fibrillation to tachycardia : effect of calcium channel blockade on the dynamics of rotating waves

1 reference

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7 January 2021

Structure and regulation of voltage-gated Ca2+ channels

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Voltage-gated T-type Ca2+ channels and heart failure.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

T-type Ca2+ current is expressed in hypertrophied adult feline left ventricular myocytes

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Calcium channel heterogeneity in canine left ventricular myocytes

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, II: model studies

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, I: experimental studies

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Sites on the cytoplasmic region of phospholamban involved in interaction with the calcium-activated ATPase of the sarcoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Dissociation of phospholamban regulation of cardiac sarcoplasmic reticulum Ca2+ATPase by quercetin

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Stimulation of sarcoplasmic reticulum Ca(2+)-ATPase by gingerol analogues

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Overwhelming evidence of the beneficial effects of SERCA gene transfer in heart failure

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Targeted gene transfer increases contractility and decreases oxygen cost of contractility in normal rat hearts.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Restoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Calcium handling proteins in the failing human heart

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Targeting phospholamban by gene transfer in human heart failure

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Phospholamban gene ablation improves calcium transients but not cardiac function in a heart failure model

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Contribution of reverse-mode sodium-calcium exchange to contractions in failing human left ventricular myocytes

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Functional properties of failing human ventricular myocytes

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Altered Na/Ca exchange activity in cardiac hypertrophy and heart failure: a new target for therapy?

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Alterations in sarcoplasmic reticulum gene expression in human heart failure. A possible mechanism for alterations in systolic and diastolic properties of the failing myocardium

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Partial inhibition of sodium/calcium exchange restores cellular calcium handling in canine heart failure

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Alterations of Sarcoplasmic Reticulum Proteins in Failing Human Dilated Cardiomyopathy

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Chronic unloading by left ventricular assist device reverses contractile dysfunction and alters gene expression in end-stage heart failure

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Activity of cAMP-dependent protein kinase and Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human hearts

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Calcium, calmodulin, and calcium-calmodulin kinase II: heartbeat to heartbeat and beyond.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Modulation of cardiac ryanodine receptors of swine and rabbit by a phosphorylation-dephosphorylation mechanism

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Increased sarcoplasmic reticulum calcium leak but unaltered contractility by acute CaMKII overexpression in isolated rabbit cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Disease mechanisms and emerging therapies: protein kinases and their inhibitors in myocardial disease

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Intracellular Na in animal models of hypertrophy and heart failure: contractile function and arrhythmogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade des pointes in LQT2 and LQT3 models of the long-QT syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Alterations of Na+ currents in myocytes from epicardial border zone of the infarcted heart. A possible ionic mechanism for reduced excitability and postrepolarization refractoriness

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Repolarization abnormalities in cardiomyocytes of dogs with chronic heart failure: role of sustained inward current

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Increased Na+/H+-exchange activity is the cause of increased [Na+]i and underlies disturbed calcium handling in the rabbit pressure and volume overload heart failure model

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

[Na+]i and the driving force of the Na+/Ca2+-exchanger in heart failure

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

The myocardial Na+/H+ exchanger: a potential therapeutic target for the prevention of myocardial ischaemic and reperfusion injury and attenuation of postinfarction heart failure

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

Clinical potential of sodium-calcium exchanger inhibitors as antiarrhythmic agents

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1130

7 January 2021

GUARD During Ischemia Against Necrosis (GUARDIAN) trial in acute coronary syndromes

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7 January 2021

Identifiers

DOI

10.1038/NCPCARDIO1130

1 reference

release_gpxz7wxilbhixohbets4wdi4cu

18 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gpxz7wxilbhixohbets4wdi4cu

24 November 2022

mapped directly with Wikidata item

1 reference