(Q37102932)

18 August 2017

Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing (English)

1 reference

18 August 2017

0 references

Zhen Shao

4

0 references

Gregory C Ippolito

object named as

Gregory C Ippolito

7

0 references

author name string

Jian Xu

1

1 reference

18 August 2017

Cong Peng

2

1 reference

18 August 2017

Vijay G Sankaran

3

1 reference

18 August 2017

Erica B Esrick

5

1 reference

18 August 2017

Bryan G Chong

6

1 reference

18 August 2017

Yuko Fujiwara

8

1 reference

18 August 2017

Benjamin L Ebert

9

1 reference

18 August 2017

Philip W Tucker

10

1 reference

18 August 2017

Stuart H Orkin

11

1 reference

18 August 2017

language of work or name

English

0 references

publication date

13 October 2011

1 reference

18 August 2017

1 reference

18 August 2017

334

1 reference

18 August 2017

6058

1 reference

18 August 2017

993-996

1 reference

Combination therapy utilizing shRNA knockdown and an optimized resistant transgene for rescue of diseases caused by misfolded proteins

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Transcriptional regulation of fetal to adult hemoglobin switching: new therapeutic opportunities

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

A complex task? Direct modulation of transcription factors with small molecules

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Direct inhibition of the NOTCH transcription factor complex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Developmental and species-divergent globin switching are driven by BCL11A

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

A specific chemical difference between the globins of normal human and sickle-cell anaemia haemoglobin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Bcl11a is essential for normal lymphoid development

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Correction of sickle cell disease in transgenic mouse models by gene therapy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Second generation knockout sickle mice: the effect of HbF.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Knocking down disease with siRNAs

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

A mouse model for visualization and conditional mutations in the erythroid lineage

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Hereditary persistence of fetal hemoglobin: a study of 79 affected persons in 15 Negro families in Baltimore

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Transgenic knockout mice with exclusively human sickle hemoglobin and sickle cell disease

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

Mortality in sickle cell disease. Life expectancy and risk factors for early death.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746545

5-Azacytidine Selectively Increases γ-Globin Synthesis in a Patient with β+Thalassemia

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21998251

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Knockout-transgenic mouse model of sickle cell disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21998251

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Two families showing interaction of haemoglobin C or thalassaemia with high foetal haemoglobin in adults

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21998251

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1211053

1 reference

18 August 2017

1 reference

18 August 2017

1 reference