(Q37111796)

18 August 2017

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title

Emerging chemotherapeutic strategies and the role of treatment stratification in Ewing sarcoma (English)

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18 August 2017

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Beatrice M Seddon

1

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18 August 2017

Jeremy S Whelan

series ordinal

2

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18 August 2017

publication date

1 January 2008

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18 August 2017

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18 August 2017

volume

10

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18 August 2017

issue

2

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18 August 2017

page(s)

93-105

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Sensitive detection of occult Ewing's cells by the reverse transcriptase-polymerase chain reaction

18 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.2165%2F00148581-200810020-00004

Retinoid targets for the treatment of cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.2165%2F00148581-200810020-00004

Depression, correlates of depression, and receipt of depression care among low-income women with breast or gynecologic cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.2165%2F00148581-200810020-00004

Temozolomide and intravenous irinotecan for treatment of advanced Ewing sarcoma

21 January 2018

1 reference

12 December 2020

Inhibition of EWS-FLI-1 fusion protein with antisense oligodeoxynucleotides

1 reference

12 December 2020

Predictive factors of histological response to primary chemotherapy in Ewing's sarcoma

1 reference

12 December 2020

Multimodal therapy for the management of primary, nonmetastatic Ewing's sarcoma of bone: a long-term follow-up of the First Intergroup study

1 reference

12 December 2020

The rapamycin-sensitive signal transduction pathway as a target for cancer therapy

1 reference

12 December 2020

p38MAPK-Dependent sensitivity of Ewing's sarcoma family of tumors to fenretinide-induced cell death

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12 December 2020

Detection of (11;22)(q24;q12) translocation-bearing cells in peripheral blood progenitor cells of patients with Ewing's sarcoma family of tumors

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12 December 2020

Does expression of different EWS chimeric transcripts define clinically distinct risk groups of Ewing tumor patients?

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12 December 2020

The use of bisphosphonates in cancer patients

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12 December 2020

The use of paediatric chemotherapy protocols at full dose is both a rational and feasible treatment strategy in adults with Ewing's family tumours.

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12 December 2020

Biology of EWS/ETS fusions in Ewing's family tumors

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12 December 2020

The predictive potential of molecular detection in the nonmetastatic Ewing family of tumors.

1 reference

12 December 2020

High-dose therapy with autologous stem cell rescue for pediatric sarcomas

1 reference

12 December 2020

Primary chemotherapy and delayed surgery (neoadjuvant chemotherapy) for osteosarcoma of the extremities. The Istituto Rizzoli Experience in 127 patients treated preoperatively with intravenous methotrexate (high versus moderate doses) and intraarter

1 reference

12 December 2020

Loss of tumorigenicity of Ewing's sarcoma cells expressing antisense RNA to EWS-fusion transcripts

1 reference

12 December 2020

Neoadjuvant chemotherapy for Ewing's sarcoma of bone: no benefit observed after adding ifosfamide and etoposide to vincristine, actinomycin, cyclophosphamide, and doxorubicin in the maintenance phase--results of two sequential studies

1 reference

12 December 2020

Where do teenagers and young adults receive treatment for cancer?

1 reference

12 December 2020

Treatment of metastatic Ewing's sarcoma or primitive neuroectodermal tumor of bone: evaluation of combination ifosfamide and etoposide--a Children's Cancer Group and Pediatric Oncology Group study

1 reference

12 December 2020

High-dose melphalan, etoposide, total-body irradiation, and autologous stem-cell reconstitution as consolidation therapy for high-risk Ewing's sarcoma does not improve prognosis.

1 reference

12 December 2020

Overexpression of the pseudoautosomal gene MIC2 in Ewing's sarcoma and peripheral primitive neuroectodermal tumor

1 reference

12 December 2020

Primary chemotherapy and delayed surgery for nonmetastatic osteosarcoma of the extremities. Results in 164 patients preoperatively treated with high doses of methotrexate followed by cisplatin and doxorubicin

1 reference

12 December 2020

Neoadjuvant chemotherapy for Ewing's tumour of bone: recent experience at the Rizzoli Orthopaedic Institute.

1 reference

12 December 2020

Blockage of insulin-like growth factor-I receptor inhibits the growth of Ewing's sarcoma in athymic mice

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12 December 2020

Contrasting levels of p21ras activation and expression of neurofibromin in peripheral primitive neuroectodermal tumour and neuroblastoma cells, and their response to retinoic acid

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12 December 2020

Total-body irradiation and autologous bone marrow transplant in the treatment of high-risk Ewing's sarcoma and rhabdomyosarcoma

1 reference

12 December 2020

High-dose busulphan/melphalan with autologous stem cell rescue in Ewing's sarcoma.

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12 December 2020

Randomised trial of two regimens of chemotherapy in operable osteosarcoma: a study of the European Osteosarcoma Intergroup

1 reference

12 December 2020

Preclinical in vivo study of new insulin-like growth factor-I receptor--specific inhibitor in Ewing's sarcoma

1 reference

12 December 2020

Prognostic factors in localized Ewing's tumours and peripheral neuroectodermal tumours: the third study of the French Society of Paediatric Oncology (EW88 study)

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12 December 2020

Interferon gamma enhances the effectiveness of tumor necrosis factor-related apoptosis-inducing ligand receptor agonists in a xenograft model of Ewing's sarcoma

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12 December 2020

How to treat the Ewing's family of sarcomas in adult patients

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12 December 2020

Predictive potential of testing for bone marrow involvement in Ewing tumor patients by RT-PCR: a preliminary evaluation.

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12 December 2020

Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone

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12 December 2020

Primary metastatic (stage IV) Ewing tumor: survival analysis of 171 patients from the EICESS studies. European Intergroup Cooperative Ewing Sarcoma Studies.

1 reference

12 December 2020

Safety assessment of intensive induction with vincristine, ifosfamide, doxorubicin, and etoposide (VIDE) in the treatment of Ewing tumors in the EURO-E.W.I.N.G. 99 clinical trial

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12 December 2020

Increased risk of systemic relapses associated with bone marrow micrometastasis and circulating tumor cells in localized ewing tumor.

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12 December 2020

Megatherapy in children with high-risk Ewing's sarcoma in first complete remission

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12 December 2020

Prognostic significance of histopathologic response to chemotherapy in nonmetastatic Ewing's sarcoma of the extremities

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12 December 2020

Detection of tumour cells in peripheral blood and bone marrow from Ewing tumour patients by RT-PCR.

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12 December 2020

Ewing's sarcoma family tumors are sensitive to tumor necrosis factor-related apoptosis-inducing ligand and express death receptor 4 and death receptor 5.

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12 December 2020

High dose chemotherapy with bone marrow or peripheral stem cell rescue is an effective treatment option for patients with relapsed or progressive Ewing's sarcoma family of tumours

1 reference

12 December 2020

Ewing's tumors with primary lung metastases: survival analysis of 114 (European Intergroup) Cooperative Ewing's Sarcoma Studies patients

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12 December 2020

Chemotherapy-induced tumor necrosis as a prognostic factor in localized Ewing's sarcoma of the extremities

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12 December 2020

Initial symptoms and clinical features in osteosarcoma and Ewing sarcoma

1 reference

12 December 2020

Treatment of nonmetastatic osteosarcoma of the extremity with preoperative and postoperative chemotherapy: a report from the Children's Cancer Group

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12 December 2020

Inhibitory effects of a new bisphosphonate, minodronate, on proliferation and invasion of a variety of malignant bone tumor cells

1 reference

12 December 2020

Deregulation of the IGF axis in cancer: epidemiological evidence and potential therapeutic interventions

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12 December 2020

EICESS 92 (European Intergroup Cooperative Ewing's Sarcoma Study)-- preliminary results

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12 December 2020

Sensitivity of Ewing's sarcoma to TRAIL-induced apoptosis

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12 December 2020

Ewing family tumors: potential prognostic value of reverse-transcriptase polymerase chain reaction detection of minimal residual disease in peripheral blood samples.

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12 December 2020

Morphological grades of regression in osteosarcoma after polychemotherapy - study COSS 80

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12 December 2020

Neoadjuvant chemotherapy of osteosarcoma: results of a randomized cooperative trial (COSS-82) with salvage chemotherapy based on histological tumor response

1 reference

12 December 2020

Localized Ewing tumor of bone: final results of the cooperative Ewing's Sarcoma Study CESS 86.

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12 December 2020

High-dose chemotherapy in poor-prognosis adult small round-cell tumors: clinical and molecular results from a prospective study

1 reference

12 December 2020

EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3.

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12 December 2020

Myeloablative radiochemotherapy and hematopoietic stem-cell rescue in poor-prognosis Ewing's sarcoma

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12 December 2020

Factors associated with tumor volume and primary metastases in Ewing tumors: results from the (EI)CESS studies

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12 December 2020

Prognostic factors in Ewing's tumor of bone: analysis of 975 patients from the European Intergroup Cooperative Ewing's Sarcoma Study Group

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12 December 2020

Small round cell tumors of bone

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12 December 2020

Survival after recurrence of Ewing's sarcoma family of tumors

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12 December 2020

Zoledronic acid inhibits primary bone tumor growth in Ewing sarcoma

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12 December 2020

Preoperative chemotherapy for osteogenic sarcoma:Selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy

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12 December 2020

Regulation of apoptosis and proliferation in Ewing's sarcoma--opportunities for targeted therapy

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12 December 2020

Multidisciplinary treatment of primary Ewing's sarcoma of bone. A 6-year experience of a European Cooperative Trial

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12 December 2020

Chemotherapy for nonmetastatic osteogenic sarcoma: the Memorial Sloan-Kettering experience

1 reference

12 December 2020

Cytotoxicity of Tumor necrosis factor related apoptosis-inducing ligand towards Ewing's sarcoma cell lines

1 reference

12 December 2020

Targeting mTOR for cancer treatment.

1 reference

12 December 2020

Multimodal therapy for the management of nonpelvic, localized Ewing's sarcoma of bone: intergroup study IESS-II

1 reference

12 December 2020

Fenretinide cytotoxicity for Ewing's sarcoma and primitive neuroectodermal tumor cell lines is decreased by hypoxia and synergistically enhanced by ceramide modulators

1 reference

12 December 2020

Impact of high-dose busulfan plus melphalan as consolidation in metastatic Ewing tumors: a study by the Société Française des Cancers de l'Enfant.

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12 December 2020

Pilot study of topotecan and high-dose cyclophosphamide for resistant pediatric solid tumors.

1 reference

12 December 2020

Insulin-like growth factor I receptor-mediated circuit in Ewing's sarcoma/peripheral neuroectodermal tumor: a possible therapeutic target

1 reference

12 December 2020

Targeted induction of apoptosis in cancer management: the emerging role of tumor necrosis factor-related apoptosis-inducing ligand receptor activating agents

1 reference

12 December 2020

How effective is dose-intensive/myeloablative therapy against Ewing's sarcoma/primitive neuroectodermal tumor metastatic to bone or bone marrow? The Memorial Sloan-Kettering experience and a literature review

1 reference

12 December 2020

The Ewing Family of Tumors -- A Subgroup of Small-Round-Cell Tumors Defined by Specific Chimeric Transcripts

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12 December 2020

IGF1R signalling and its inhibition

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12 December 2020

Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors.

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12 December 2020

Potentials for RNAi in sarcoma research and therapy: Ewing's sarcoma as a model.

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12 December 2020

CD99 engagement: an effective therapeutic strategy for Ewing tumors

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12 December 2020

A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG

1 reference

12 December 2020

Molecular mechanisms of CD99-induced caspase-independent cell death and cell-cell adhesion in Ewing's sarcoma cells: actin and zyxin as key intracellular mediators.

1 reference

12 December 2020

The bisphosphonate pamidronate is a potent inhibitor of Ewing's sarcoma cell growth in vitro

1 reference

12 December 2020

Neoadjuvant chemotherapy for Ewing's sarcoma of bone in patients older than thirty-nine years

1 reference

12 December 2020

Establishing long-term survival and cure in young patients with Ewing's sarcoma

1 reference

12 December 2020

Five-year results in Ewing's sarcoma. The Scandinavian Sarcoma Group experience with the SSG IX protocol

1 reference

12 December 2020

Mesenchymal stem cell features of Ewing tumors

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12 December 2020

Combinatorial generation of variable fusion proteins in the Ewing family of tumours.

1 reference

12 December 2020

EWS/FLI-1 antagonists induce growth inhibition of Ewing tumor cells in vitro

1 reference

12 December 2020

A comparison of two short intensive adjuvant chemotherapy regimens in operable osteosarcoma of limbs in children and young adults: the first study of the European Osteosarcoma Intergroup

1 reference

12 December 2020

Small interfering RNAs expressed from a Pol III promoter suppress the EWS/Fli-1 transcript in an Ewing sarcoma cell line

1 reference

12 December 2020

EWS-FLI1 fusion transcript structure is an independent determinant of prognosis in Ewing's sarcoma

1 reference

12 December 2020

EWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells

1 reference

12 December 2020

Targeting CD99 in association with doxorubicin: an effective combined treatment for Ewing's sarcoma

1 reference

12 December 2020

Prognostic factors in non-metastatic Ewing's sarcoma tumor of bone: an analysis of 579 patients treated at a single institution with adjuvant or neoadjuvant chemotherapy between 1972 and 1998.

1 reference

12 December 2020

Phase I trial of temozolomide and protracted irinotecan in pediatric patients with refractory solid tumors

1 reference

12 December 2020

Cyclophosphamide plus topotecan in children with recurrent or refractory solid tumors: a Pediatric Oncology Group phase II study

1 reference

12 December 2020

Long-term results from the first UKCCSG Ewing's Tumour Study (ET-1). United Kingdom Children's Cancer Study Group (UKCCSG) and the Medical Research Council Bone Sarcoma Working Party

1 reference

12 December 2020

High-dose therapy for patients with primary multifocal and early relapsed Ewing's tumors: results of two consecutive regimens assessing the role of total-body irradiation

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12 December 2020

Apoptotic responsiveness of the Ewing's sarcoma family of tumours to tumour necrosis factor-related apoptosis-inducing ligand (TRAIL).

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12 December 2020

Intensive therapy with growth factor support for patients with Ewing tumor metastatic at diagnosis: Pediatric Oncology Group/Children's Cancer Group Phase II Study 9457--a report from the Children's Oncology Group

1 reference

12 December 2020

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

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12 December 2020

Chromosomes in Ewing's sarcoma. I. An evaluation of 85 cases of remarkable consistency of t(11;22)(q24;q12)

1 reference

12 December 2020

Ifosfamide-containing chemotherapy in Ewing's sarcoma: The Second United Kingdom Children's Cancer Study Group and the Medical Research Council Ewing's Tumor Study

1 reference

12 December 2020

EWS-FLI1 and EWS-ERG gene fusions are associated with similar clinical phenotypes in Ewing's sarcoma.

1 reference

12 December 2020

MIC2 is a specific marker for ewing's sarcoma and peripheral primitive neuroectodermal tumors. Evidence for a common histogenesis of ewing's sarcoma and peripheral primitive neuroectodermal tumors from MIC2 expression and specific chromosome aberrati

1 reference

12 December 2020

Detection of circulating tumor cells in patients with Ewing's sarcoma and peripheral primitive neuroectodermal tumor

1 reference

12 December 2020

Where should teenagers with cancer be treated?

1 reference

12 December 2020

Presence of tumor cells in bone marrow but not in blood is associated with adverse prognosis in patients with Ewing's tumor. Société Française d'Oncologie Pédiatrique

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12 December 2020

Rapamycin induces the fusion-type independent downregulation of the EWS/FLI-1 proteins and inhibits Ewing's sarcoma cell proliferation

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12 December 2020

10.2165/00148581-200810020-00004

Identifiers

DOI

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Dimensions Publication ID

18 August 2017

1005541377

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