(Q37113691)

18 August 2017

Microtubule binding and disruption and induction of premature senescence by disorazole C(1). (English)

1 reference

18 August 2017

15

John S Lazo

1 reference

18 August 2017

5

Peter Wipf

1 reference

18 August 2017

14

Celeste E Reese

1 reference

18 August 2017

13

Alexander P Ducruet

1 reference

18 August 2017

2

Carolyn A Kitchens

1 reference

18 August 2017

Marni Brisson Tierno

1

1 reference

18 August 2017

Bethany Petrik

3

1 reference

18 August 2017

Thomas H Graham

4

1 reference

18 August 2017

Fengfeng L Xu

6

1 reference

18 August 2017

William S Saunders

7

1 reference

18 August 2017

Brianne S Raccor

8

1 reference

18 August 2017

Raghavan Balachandran

9

1 reference

18 August 2017

Billy W Day

10

1 reference

18 August 2017

Jane R Stout

11

1 reference

18 August 2017

Claire E Walczak

12

1 reference

18 August 2017

language of work or name

English

0 references

publication date

9 December 2008

1 reference

Journal of Pharmacology and Experimental Therapeutics

18 August 2017

1 reference

18 August 2017

328

1 reference

18 August 2017

715-722

1 reference

18 August 2017

3

1 reference

Spindle checkpoint function and cellular sensitivity to antimitotic drugs

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Cellular senescence and cancer treatment.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Deciphering protein function during mitosis in PtK cells using RNAi

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Senescence-associated beta-galactosidase is lysosomal beta-galactosidase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Cellular analysis of disorazole C and structure-activity relationship of analogs of the natural product

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Production of the tubulin destabilizer disorazol in Sorangium cellulosum: biosynthetic machinery and regulatory genes.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

The microtubule stabilizing agent discodermolide is a potent inducer of accelerated cell senescence

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Microtubules as a target for anticancer drugs

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Tumor cell senescence in cancer treatment

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Cell senescence and hypermitogenic arrest

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Autophagic cell death, polyploidy and senescence induced in breast tumor cells by the substituted pyrrole JG-03-14, a novel microtubule poison

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Structure-activity and high-content imaging analyses of novel tubulysins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Two distinct modes of cell death induced by doxorubicin: apoptosis and cell death through mitotic catastrophe accompanied by senescence-like phenotype

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Disorazol A1, a highly effective antimitotic agent acting on tubulin polymerization and inducing apoptosis in mammalian cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Correlation between methylation status of the p16/CDKN2 gene and the expression of p16 and Rb proteins in primary non-small cell lung cancers.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Separation of active tubulin and microtubule-associated proteins by ultracentrifugation and isolation of a component causing the formation of microtubule bundles.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Cancer Regression by Senescence

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649750

Total synthesis of (-)-disorazole C1

4 December 2018

1 reference

12 December 2020

Interaction of dolastatin 10 with tubulin: induction of aggregation and binding and dissociation reactions

1 reference

12 December 2020

The spongistatins, potently cytotoxic inhibitors of tubulin polymerization, bind in a distinct region of the vinca domain

1 reference

12 December 2020

Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts

1 reference

12 December 2020

A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents

1 reference

12 December 2020

Antibiotics from Gliding Bacteria, LIX. Disorazoles, Highly Cytotoxic Metabolites from the Sorangicin-Producing BacteriumSorangium Cellulosum, Strain So ce12

1 reference

COCI

https://opencitations.net/index/api/v1/citations/10.1002/JLAC.199419940802

9 March 2024

Identifiers

DOI

10.1124/JPET.108.147330

1 reference

18 August 2017

1 reference

18 August 2017

1 reference