(Q37125668)

English

Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-twitch response model

scientific article published on 23 January 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-twitch response model (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

author name string

Clinton E Canal

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Raymond G Booth

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Drake Morgan

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

publication date

23 January 2013

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Europe PubMed Central

PMC publication ID

18 August 2017

Neuropharmacology

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Europe PubMed Central

PMC publication ID

18 August 2017

70

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Europe PubMed Central

PMC publication ID

18 August 2017

112-121

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Oligomer size of the serotonin 5-hydroxytryptamine 2C (5-HT2C) receptor revealed by fluorescence correlation spectroscopy with photon counting histogram analysis: evidence for homodimers without monomers or tetramers

1 reference

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Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor

1 reference

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Head-twitch response in rodents induced by the hallucinogen 2,5-dimethoxy-4-iodoamphetamine: a comprehensive history, a re-evaluation of mechanisms, and its utility as a model

1 reference

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Receptor conformations involved in dopamine D(2L) receptor functional selectivity induced by selected transmembrane-5 serine mutations

1 reference

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The plasticity of the 7TMR signaling machinery and the search for pharmacological selectivity

1 reference

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Drug discovery targeting human 5-HT(2C) receptors: residues S3.36 and Y7.43 impact ligand-binding pocket structure via hydrogen bond formation

1 reference

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1 reference

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Serotonin 2A receptor antagonists for treatment of schizophrenia

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1 reference

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1 reference

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1 reference

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1 reference

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Interaction of 5-HT2A and 5-HT2C Receptors in R(−)-2,5-Dimethoxy-4-iodoamphetamine-Elicited Head Twitch Behavior in Mice

1 reference

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Serotonin 5-HT(2A) receptor antagonists in the treatment of insomnia: present status and future prospects

1 reference

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The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen

1 reference

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Psychedelics and the human receptorome

1 reference

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The serotonin 5-HT(2A) receptor agonist TCB-2: a behavioral and neurophysiological analysis

1 reference

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PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors

1 reference

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14 September 2017

Antagonism of serotonergic 5-HT2A/2C receptors: mutual improvement of sleep, cognition and mood?

1 reference

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14 September 2017

(1R, 3S)-(-)-trans-PAT: a novel full-efficacy serotonin 5-HT2C receptor agonist with 5-HT2A and 5-HT2B receptor inverse agonist/antagonist activity

1 reference

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14 September 2017

5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice

1 reference

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14 September 2017

Old and new pharmacology: positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine(2B/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']di pyrrole-1(2H)-carboxamide)

1 reference

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Pimavanserin tartrate: a 5-HT2A inverse agonist with potential for treating various neuropsychiatric disorders

1 reference

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Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells

1 reference

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5-HT(2A) inverse-agonists for the treatment of insomnia

1 reference

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Identification of a serotonin/glutamate receptor complex implicated in psychosis

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Lorcaserin, a novel selective human 5-hydroxytryptamine2C agonist: in vitro and in vivo pharmacological characterization

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Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivo

1 reference

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5-HT2C receptor agonists as an innovative approach for psychiatric disorders

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GPCR functional selectivity has therapeutic impact

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Role of G(q) protein in behavioral effects of the hallucinogenic drug 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane

1 reference

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Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors

1 reference

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Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior

1 reference

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CP-809,101, a selective 5-HT2C agonist, shows activity in animal models of antipsychotic activity

1 reference

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Functional Selectivity and Classical Concepts of Quantitative Pharmacology

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Serotonin 5-HT2C receptors as a target for the treatment of depressive and anxious states: focus on novel therapeutic strategies

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1 reference

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1 reference

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1 reference

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Neuroendocrine evidence that (S)-2-(chloro-5-fluoro-indol- l-yl)-1-methylethylamine fumarate (Ro 60-0175) is not a selective 5-hydroxytryptamine(2C) receptor agonist.

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Regulation of serotonin-2C receptor G-protein coupling by RNA editing

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Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines

1 reference

https://pubmed.ncbi.nlm.nih.gov/23353901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological and behavioral characterization of the 5-HT2A receptor in C57BL/6N mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23353901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.NEUROPHARM.2013.01.007

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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