(Q37129813)

18 August 2017

1 reference

title

Forkhead transcription factors and ageing (English)

1 reference

18 August 2017

L Partridge

1

1 reference

PubMed ID

18391977

18 August 2017

J C Brüning

series ordinal

2

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PubMed ID

18391977

18 August 2017

language of work or name

English

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publication date

1 April 2008

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18 August 2017

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18 August 2017

27

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18 August 2017

2351-2363

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18 August 2017

16

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https://scigraph.springernature.com/pub.10.1038/onc.2008.28

18 August 2017

0 references

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Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction

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Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands

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21 January 2018

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14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport

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Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 January 2018

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Cell cycle and death control: long live Forkheads

21 January 2018

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Age of ovary determines remaining life expectancy in old ovariectomized mice

21 January 2018

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WAF1, a potential mediator of p53 tumor suppression

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FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

21 January 2018

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Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes

21 January 2018

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The Foxa family of transcription factors in development and metabolism

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Dynamics of the action of dFOXO on adult mortality in Drosophila.

21 January 2018

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An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans

21 January 2018

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The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor

21 January 2018

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A systematic RNAi screen for longevity genes in C. elegans

21 January 2018

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Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans

21 January 2018

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21 January 2018

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21 January 2018

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IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

21 January 2018

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Signals from the reproductive system regulate the lifespan of C. elegans

21 January 2018

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21 January 2018

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Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

21 January 2018

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The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling

21 January 2018

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The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

21 January 2018

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Lifespan extension in Caenorhabditis elegans by complete removal of food.

21 January 2018

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21 January 2018

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21 January 2018

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A C. elegans mutant that lives twice as long as wild type

21 January 2018

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daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

21 January 2018

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FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction

21 January 2018

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Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake

21 January 2018

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A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results

21 January 2018

1 reference

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Expression of Drosophila FOXO regulates growth and can phenocopy starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Suppression of aging in mice by the hormone Klotho

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Pax3-FKHR knock-in mice show developmental aberrations but do not develop tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

DAF-16 target genes that control C. elegans life-span and metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Dietary deprivation extends lifespan in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

The 14-3-3 protein FTT-2 regulates DAF-16 in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Regulation of Drosophila life span by olfaction and food-derived odors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Foxa3 (HNF-3gamma) binds to and activates the rat proglucagon gene promoter but is not essential for proglucagon gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Demography of dietary restriction and death in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

IRES-mediated functional coupling of transcription and translation amplifies insulin receptor feedback

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Evolutionary conservation of regulated longevity assurance mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Glucocorticoid receptor-mediated protection from apoptosis is associated with induction of the serine/threonine survival kinase gene, sgk-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Mammalian SIRT1 represses forkhead transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Nuclear forkhead box O1 controls and integrates key signaling pathways in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

The forkhead transcription factor Foxo1 regulates adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Immune regulation by Foxo transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

The coactivator p300 directly acetylates the forkhead transcription factor Foxo1 and stimulates Foxo1-induced transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Transcriptional feedback control of insulin receptor by dFOXO/FOXO1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Nutrient availability and growth: regulation of insulin signaling by dFOXO/FOXO1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Conserved and tissue-specific genic and physiologic responses to caloric restriction and altered IGFI signaling in mitotic and postmitotic tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Regulation of PTEN transcription by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Brain IRS2 signaling coordinates life span and nutrient homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Forkhead transcription factors II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

SnapShot: forkhead transcription factors I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Stressing the role of FoxO proteins in lifespan and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

JNK Signaling Confers Tolerance to Oxidative Stress and Extends Lifespan in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

The fork head domain: a novel DNA binding motif of eukaryotic transcription factors?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Insulin regulation of heart function in aging fruit flies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

SMK-1, an essential regulator of DAF-16-mediated longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Regulation of C. elegans life-span by insulinlike signaling in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

p53-dependent inhibition of FKHRL1 in response to DNA damage through protein kinase SGK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

PUMA induces the rapid apoptosis of colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Systems biology of aging in four species

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Phylogenetic relationships of the Fox (Forkhead) gene family in the Bilateria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Benchmarks for ageing studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Hepatic and glucagon-like peptide-1-mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Foxa1-deficient mice exhibit impaired insulin secretion due to uncoupled oxidative phosphorylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

Role of Foxa-2 in adipocyte metabolism and differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.28

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.28

1 reference

18 August 2017

1 reference

PubMed ID

18391977