(Q37129918)

English

HtrA, a Temperature- and Stationary Phase-Activated Protease Involved in Maturation of a Key Microbial Virulence Determinant, Facilitates Borrelia burgdorferi Infection in Mammalian Hosts

scientific article published on 06 June 2016

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scholarly article

1 reference

Europe PubMed Central

18 August 2017

HtrA, a Temperature- and Stationary Phase-Activated Protease Involved in Maturation of a Key Microbial Virulence Determinant, Facilitates Borrelia burgdorferi Infection in Mammalian Hosts (English)

1 reference

Europe PubMed Central

18 August 2017

Borrelia burgdorferi

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author name string

Meiping Ye

1

1 reference

Europe PubMed Central

18 August 2017

Kavita Sharma

2

1 reference

Europe PubMed Central

18 August 2017

Meghna Thakur

3

1 reference

Europe PubMed Central

18 August 2017

Alexis A Smith

4

1 reference

Europe PubMed Central

18 August 2017

Ozlem Buyuktanir

5

1 reference

Europe PubMed Central

18 August 2017

Xuwu Xiang

6

1 reference

Europe PubMed Central

18 August 2017

Xiuli Yang

7

1 reference

Europe PubMed Central

18 August 2017

Kamoltip Promnares

8

1 reference

Europe PubMed Central

18 August 2017

Yongliang Lou

9

1 reference

Europe PubMed Central

18 August 2017

X Frank Yang

10

1 reference

Europe PubMed Central

18 August 2017

Utpal Pal

11

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Europe PubMed Central

18 August 2017

language of work or name

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publication date

6 June 2016

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Europe PubMed Central

18 August 2017

Infection and Immunity

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Europe PubMed Central

18 August 2017

84

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Europe PubMed Central

18 August 2017

8

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Europe PubMed Central

18 August 2017

2372-2381

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Europe PubMed Central

18 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4962642/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Borrelia burgdorferi elongation factor EF-Tu is an immunogenic protein during Lyme borreliosis.

1 reference

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Lyme Disease Diagnosis: Serology

1 reference

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The Borrelia burgdorferi RelA/SpoT Homolog and Stringent Response Regulate Survival in the Tick Vector and Global Gene Expression during Starvation

1 reference

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Borrelia burgdorferi HtrA: evidence for twofold proteolysis of outer membrane protein p66.

1 reference

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Morphological and biochemical features of Borrelia burgdorferi pleomorphic forms

1 reference

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BB0323 and novel virulence determinant BB0238: Borrelia burgdorferi proteins that interact with and stabilize each other and are critical for infectivity

1 reference

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Borrelia burgdorferi HtrA may promote dissemination and irritation

1 reference

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The lipoprotein La7 contributes to Borrelia burgdorferi persistence in ticks and their transmission to naïve hosts

1 reference

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The HtrA protease of Borrelia burgdorferi degrades outer membrane protein BmpD and chemotaxis phosphatase CheX.

1 reference

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The emerging roles of HTRA1 in musculoskeletal disease.

1 reference

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Proteolysis of BB0323 results in two polypeptides that impact physiologic and infectious phenotypes in Borrelia burgdorferi

1 reference

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1 reference

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Borrelia burgdorferi and tick proteins supporting pathogen persistence in the vector

1 reference

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HtrA protease family as therapeutic targets

1 reference

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Borrelia burgdorferi requires the alternative sigma factor RpoS for dissemination within the vector during tick-to-mammal transmission

1 reference

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Whole-genome sequences of two Borrelia afzelii and two Borrelia garinii Lyme disease agent isolates.

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HTRA proteases: regulated proteolysis in protein quality control

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1 reference

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Helicobacter pylori HtrA is a new secreted virulence factor that cleaves E-cadherin to disrupt intercellular adhesion

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Characterization of unique regions of Borrelia burgdorferi surface-located membrane protein 1.

1 reference

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14 September 2017

HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues

1 reference

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HtrA proteins as targets in therapy of cancer and other diseases.

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BBA52 facilitates Borrelia burgdorferi transmission from feeding ticks to murine hosts

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Destruction of spirochete Borrelia burgdorferi round-body propagules (RBs) by the antibiotic tigecycline

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Proteases in bacterial pathogenesis

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BB0323 function is essential for Borrelia burgdorferi virulence and persistence through tick-rodent transmission cycle

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A chromosomally encoded virulence factor protects the Lyme disease pathogen against host-adaptive immunity

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The yeast HtrA orthologue Ynm3 is a protease with chaperone activity that aids survival under heat stress

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Chronic Lyme disease: a review

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Role of HtrA in the virulence and competence of Streptococcus pneumoniae

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The emergence of Lyme disease

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Essential role for OspA/B in the life cycle of the Lyme disease spirochete

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OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands

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The HtrA Family of Proteases

1 reference

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Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi

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The HtrA (DegP) protein, essential for Escherichia coli survival at high temperatures, is an endopeptidase

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The salt-sensitive structure and zinc inhibition of Borrelia burgdorferi protease BbHtrA.

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The role of a stress-response protein in Salmonella typhimurium virulence

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27 June 2018

Lyme disease spirochaetes possess an aggrecan-binding protease with aggrecanase activity

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HtrA is a major virulence determinant of Bacillus anthracis

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Identifiers

10.1128/IAI.00360-16

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

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