(Q37132811)

18 August 2017

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title

Serotonin pharmacology in the gastrointestinal tract: a review (English)

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18 August 2017

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1 reference

D T Beattie

1

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18 August 2017

J A M Smith

series ordinal

2

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18 August 2017

publication date

9 April 2008

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Naunyn-Schmiedeberg's Archives of Pharmacology

18 August 2017

published in

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18 August 2017

volume

377

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18 August 2017

issue

3

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18 August 2017

page(s)

181-203

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https://scigraph.springernature.com/pub.10.1007/s00210-008-0276-9

18 August 2017

exact match

0 references

cites work

Comparative efficacy of a single oral dose of ondansetron and of buspirone against cisplatin-induced emesis in cancer patients

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

Differences between 5-HT3 receptor antagonists in modulation of visceral hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

Functional evidence for a 5‐HT2B receptor mediating contraction of longitudinal muscle in human small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

5-Hydroxytryptamine (5-HT) mediates potent relaxation in the sheep isolated pulmonary vein via activation of 5-HT4 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

Drug-induced defaecation in rats: role of central 5-HT1A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

Efficacy of Ondansetron (Gr 38032F) and the Role of Serotonin in Cisplatin-Induced Nausea and Vomiting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

Impaired osmotic sensation in mice lacking TRPV4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

Mediation by 5-hydroxytryptamine2B receptors of endothelium-dependent relaxation in rat jugular vein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

GR113808: a novel, selective antagonist with high affinity at the 5-HT4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

Reciprocal activity of longitudinal and circular muscle during intestinal peristaltic reflex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

The function of 5-HT3 receptors on colonic transit in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

The effects of renzapride, a novel prokinetic agent, in diabetic gastroparesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

The cardiovascular safety profile of renzapride, a novel treatment for irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

Investigation into the 5-hydroxytryptamine receptor mediating smooth muscle relaxation in the rat oesophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

Gastroprokinetic properties of the benzimidazolone derivative BIMU 1, an agonist at 5-hydroxytryptamine4 and antagonist at 5-hydroxytryptamine3 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

Constipation evoked by 5-HT3-receptor antagonism: evidence for heterogeneous efficacy among different antagonists in guinea-pigs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

Acute tryptophan depletion alters gastrointestinal and anxiety symptoms in irritable bowel syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

Effects of tegaserod on Fos, substance P and calcitonin gene-related peptide expression induced by colon inflammation in lumbarsacral spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

Characterization of the 5-hydroxytryptamine receptor type involved in inhibition of spontaneous activity of human isolated colonic circular muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

The guinea-pig distal colon--a sensitive preparation for the investigation of 5-HT4 receptor-mediated contractions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

Selective and functional 5-hydroxytryptamine4 receptor antagonism by SB 207266

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-008-0276-9

Functional gastroduodenal disorders

21 January 2018

1 reference

12 December 2020

Pharmacological properties of 3-amino-5,6,7,8-tetrahydro-2-[4-[4-(quinolin-2-yl)piperazin-1-yl]butyl]quinazolin-4(3H)-one (TZB-30878), a novel therapeutic agent for diarrhea-predominant irritable bowel syndrome (IBS) and its effects on an experiment

1 reference

12 December 2020

Alterations in expression of p11 and SERT in mucosal biopsy specimens of patients with irritable bowel syndrome

1 reference

12 December 2020

Tegaserod, a 5-HT4 receptor partial agonist, decreases sensitivity to rectal distension in healthy subjects

1 reference

12 December 2020

Effect of sumatriptan, a 5HT1 agonist, on the frequency of transient lower esophageal sphincter relaxations and gastroesophageal reflux in healthy subjects.

1 reference

12 December 2020

5-Hydroxytryptamine receptor subtype messenger RNAs in human dorsal root ganglia: a polymerase chain reaction study

1 reference

12 December 2020

The 5-hydroxytryptamine(4a) receptor is palmitoylated at two different sites, and acylation is critically involved in regulation of receptor constitutive activity

1 reference

12 December 2020

Effect of tegaserod on gut transit in male and female subjects

1 reference

12 December 2020

A novel rat serotonin (5-HT6) receptor: molecular cloning, localization and stimulation of cAMP accumulation

1 reference

12 December 2020

Molecular cloning and functional characterization of a human 5-HT1B serotonin receptor: A homologue of the rat 5-HT1B receptor with 5-HT1D-like pharmacological specificity

1 reference

12 December 2020

5-HT2B receptors do not modulate sensitivity to colonic distension in rats with acute colorectal hypersensitivity

1 reference

12 December 2020

Identification of cells that express 5-hydroxytryptamine1A receptors in the nervous systems of the bowel and pancreas

1 reference

12 December 2020

Tegaserod inhibits the serotonin transporter SERT

1 reference

12 December 2020

Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization

1 reference

12 December 2020

Structure of the human serotonin 5-HT4 receptor gene and cloning of a novel 5-HT4 splice variant

1 reference

12 December 2020

The cost-effectiveness of psychotherapy and paroxetine for severe irritable bowel syndrome

1 reference

12 December 2020

Slow excitatory post-synaptic potentials in myenteric AH neurons of the guinea-pig ileum are reduced by the 5-hydroxytryptamine7 receptor antagonist SB 269970.

1 reference

12 December 2020

5-HT4 receptor antagonism in irritable bowel syndrome: effect of SB-207266-A on rectal sensitivity and small bowel transit

1 reference

12 December 2020

Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor

1 reference

12 December 2020

Recent advances on the importance of the serotonin transporter SERT in the rat intestine.

1 reference

12 December 2020

Cloning, pharmacological characterisation and tissue distribution of a novel 5-HT4 receptor splice variant, 5-HT4(i).

1 reference

12 December 2020

Uptake of serotonin at the apical and basolateral membranes of human intestinal epithelial (Caco-2) cells occurs through the neuronal serotonin transporter (SERT).

1 reference

12 December 2020

Guinea pig 5-HT transporter: cloning, expression, distribution, and function in intestinal sensory reception

1 reference

12 December 2020

Identification of neurons that express 5-hydroxytryptamine4 receptors in intestine

1 reference

12 December 2020

Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters

1 reference

12 December 2020

Effects of prucalopride on colonic transit, anorectal function and bowel habits in patients with chronic constipation

1 reference

12 December 2020

Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype

1 reference

12 December 2020

The role of 5-HT on the cardiovascular and renal systems and the clinical potential of 5-HT modulation

1 reference

12 December 2020

The influence of the novel 5-HT1A agonist R137696 on the proximal stomach function in healthy volunteers.

1 reference

12 December 2020

Serotonin activates electrolyte transport via 5-HT2A receptor in rat colonic crypt cells

1 reference

12 December 2020

The medical benefit of 5-HT research

1 reference

12 December 2020

Distinct 5-HT receptors mediate the peristaltic reflex induced by mucosal stimuli in human and guinea pig intestine

1 reference

12 December 2020

A placebo-controlled trial of the 5-HT1A agonist R-137696 on symptoms, visceral hypersensitivity and on impaired accommodation in functional dyspepsia

1 reference

12 December 2020

Influence of acute serotonin reuptake inhibition on colonic sensorimotor function in man.

1 reference

12 December 2020

The 5-HT4 antagonist R216073 does not affect gastric motor and sensory function in patients with functional dyspepsia

1 reference

12 December 2020

5-hydroxytryptamine 2B receptor regulates cell-cycle progression: cross-talk with tyrosine kinase pathways

1 reference

12 December 2020

Expression of 5-HT3 receptors by extrinsic duodenal afferents contribute to intestinal inhibition of gastric emptying

1 reference

12 December 2020

Pilot study of the efficacy of renzapride on gastrointestinal motility and symptoms in patients with constipation-predominant irritable bowel syndrome

1 reference

12 December 2020

Characterization of the human 5-hydroxytryptamine1B receptor

1 reference

12 December 2020

5-HT(3)-receptor antagonists in the management of nausea and vomiting in cancer and cancer treatment

1 reference

12 December 2020

Molecular, pharmacological and functional diversity of 5-HT receptors

1 reference

12 December 2020

5-HT receptors on interstitial cells of Cajal, smooth muscle and enteric nerves.

1 reference

12 December 2020

A sensitive method for the assay of 5-hydroxytryptamine

1 reference

12 December 2020

Prucalopride, a systemic enterokinetic, for the treatment of constipation

1 reference

12 December 2020

Neurotransmitters mediating the intestinal peristaltic reflex in the mouse

1 reference

12 December 2020

The pharmacological properties of the novel selective 5-HT3 receptor antagonist, alosetron, and its effects on normal and perturbed small intestinal transit in the fasted rat.

1 reference

12 December 2020

Efficacy of alosetron in irritable bowel syndrome: a meta-analysis of randomized controlled trials

1 reference

12 December 2020

International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin)

1 reference

12 December 2020

Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs.

1 reference

12 December 2020

Long-term efficacy of oral cisapride in symptomatic upper gut dysmotility.

1 reference

12 December 2020

Functions of peripheral 5-hydroxytryptamine receptors, especially 5-hydroxytryptamine4 receptor, in gastrointestinal motility

1 reference

12 December 2020

Pharmacological characterization of 5-HT4 receptors mediating relaxation of canine isolated rectum circular smooth muscle

1 reference

12 December 2020

Cloning, expression and pharmacology of a truncated splice variant of the human 5-HT7 receptor (h5-HT7b)

1 reference

12 December 2020

Tissue-specific alternative promoters of the serotonin receptor gene HTR3B in human brain and intestine.

1 reference

12 December 2020

5-HT3-receptor antagonist inhibits visceral pain differently in chemical and mechanical stimuli in rats

1 reference

12 December 2020

Review article: tegaserod

1 reference

12 December 2020

Serotonin and its role in colonic function and in gastrointestinal disorders

1 reference

12 December 2020

The effect of the 5-HT3 receptor antagonist, alosetron, on brain responses to visceral stimulation in irritable bowel syndrome patients

1 reference

12 December 2020

Alosetron: ischemic colitis and serious complications of constipation

1 reference

12 December 2020

The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution

1 reference

12 December 2020

No hypothermic response to serotonin in 5-HT7 receptor knockout mice

1 reference

12 December 2020

Functional esophageal disorders

1 reference

12 December 2020

Influence of 5-HT1 receptor agonists on feline stomach relaxation

1 reference

12 December 2020

Serotonergic modulation of murine fundic tone

1 reference

12 December 2020

The 5-HT(3) receptor antagonist alosetron inhibits the colorectal distention induced depressor response and spinal c-fos expression in the anaesthetised rat.

1 reference

12 December 2020

Pharmacologic therapy for the irritable bowel syndrome

1 reference

12 December 2020

Mediation of 5-HT-induced internal carotid vasodilatation in GR127935- and ritanserin-pretreated dogs by 5-HT7 receptors

1 reference

12 December 2020

Serotonin increases protective duodenal bicarbonate secretion via enteric ganglia and a 5-HT4-dependent pathway

1 reference

12 December 2020

Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase

1 reference

12 December 2020

Tegaserod, a 5-HT(4) receptor partial agonist, relieves symptoms in irritable bowel syndrome patients with abdominal pain, bloating and constipation

1 reference

12 December 2020

Effects of the 5-HT3 antagonist cilansetron vs placebo on phasic sigmoid colonic motility in healthy man: a double-blind crossover trial

1 reference

12 December 2020

Nitric oxide is produced via 5-HT1B and 5-HT2B receptor activation in human coronary artery endothelial cells

1 reference

12 December 2020

Irritable bowel syndrome: new agents targeting serotonin receptor subtypes

1 reference

12 December 2020

1 reference

12 December 2020

Motor dysfunction of the small bowel and colon in patients with the carcinoid syndrome and diarrhea.

1 reference

12 December 2020

Expression and function of 5-HT4 receptors in the mouse enteric nervous system

1 reference

12 December 2020

Efficacy and safety of alosetron in women with irritable bowel syndrome: a randomised, placebo-controlled trial

1 reference

12 December 2020

The 5-HT3B subunit is a major determinant of serotonin-receptor function

1 reference

12 December 2020

Neurochemical classification of myenteric neurons in the guinea-pig ileum

1 reference

12 December 2020

Gastrointestinal prokinetic benzamides: the pharmacology underlying stimulation of motility

1 reference

12 December 2020

Effect of alosetron on left colonic motility in non-constipated patients with irritable bowel syndrome and healthy volunteers

1 reference

12 December 2020

Treatment of nausea and vomiting: gaps in our knowledge.

1 reference

12 December 2020

The importance of 5-hydroxytryptamine receptors in the gut.

1 reference

12 December 2020

The role of the abdominal visceral innervation and 5-hydroxytryptamine M-receptors in vomiting induced by the cytotoxic drugs cyclophosphamide and cis-platin in the ferret

1 reference

12 December 2020

Evidence for 5-HT7 receptors mediating relaxation of human colonic circular smooth muscle

1 reference

12 December 2020

Adverse reactions of selective serotonin reuptake inhibitors: reports from a spontaneous reporting system

1 reference

12 December 2020

Are all 5-HT3 receptor antagonists the same?

1 reference

12 December 2020

Causes and treatment of functional dyspepsia

1 reference

12 December 2020

Peripheral neural serotonin receptors: identification and characterization with specific antagonists and agonists

1 reference

12 December 2020

Evaluation of whole blood serotonin and plasma and urine 5-hydroxyindole acetic acid in diagnosis of carcinoid disease

1 reference

12 December 2020

Palonosetron: a second-generation 5-hydroxytryptamine receptor antagonist

1 reference

12 December 2020

5-hydroxytryptamine receptors in the human cardiovascular system

1 reference

12 December 2020

Effects of a serotonin 5-HT(4) receptor antagonist SB-207266 on gastrointestinal motor and sensory function in humans

1 reference

12 December 2020

Exogenous serotonin regulates proliferation of interstitial cells of Cajal in mouse jejunum through 5-HT2B receptors

1 reference

12 December 2020

In vivo characterization of 5‐HT1A receptor‐mediated gastric relaxation in conscious dogs

1 reference

12 December 2020

Fibrotic valvular heart disease is not related to chemical class but to biological function: 5-HT2B receptor activation plays crucial role

1 reference

12 December 2020

5-Hydroxytryptamine and human small intestinal motility: effect of inhibiting 5-hydroxytryptamine reuptake

1 reference

12 December 2020

The 5-HT4 receptor agonist, tegaserod, is a potent 5-HT2B receptor antagonist in vitro and in vivo

1 reference

12 December 2020

Pharmacological characterization of 5-Hydroxytryptamine-receptor subtypes in circular muscle from the rat stomach.

1 reference

12 December 2020

Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans

1 reference

12 December 2020

Effect of prucalopride, a new enterokinetic agent, on gastrointestinal transit and anorectal function in healthy volunteers

1 reference

12 December 2020

Selectivity of 5-HT3 receptor antagonists and anti-emetic mechanisms of action

1 reference

12 December 2020

5-Hydroxytryptamine-induced Cl- transport is mediated by 5-HT3 and 5-HT4 receptors in the rat distal colon

1 reference

12 December 2020

5-Hydroxytryptamine effects in the gut: the 3, 4, and 7 receptors

1 reference

12 December 2020

5-HT(2A) receptors: location and functional analysis in intestines of wild-type and 5-HT(2A) knockout mice

1 reference

12 December 2020

The functional gastrointestinal disorders and the Rome III process

1 reference

12 December 2020

5-HT1D and 5-HT2B receptors mediate contraction of smooth muscle in human small intestine

1 reference

12 December 2020

The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound

1 reference

12 December 2020

Sumatriptan is an agonist at 5-HT receptors on myenteric neurones in the guinea-pig gastric antrum

1 reference

12 December 2020

Actions of 5-hydroxytryptamine on myenteric neurons in guinea pig gastric antrum

1 reference

12 December 2020

Involvement of the serotonin 5-HT2B receptor in cardiac hypertrophy linked to sympathetic stimulation: control of interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha cytokine production by ventricular fibroblasts

1 reference

12 December 2020

Signal transduction pathways for serotonin as an intestinal secretagogue

1 reference

12 December 2020

Colonic transit in man is slowed by ondansetron (GR38032F), a selective 5-hydroxytryptamine receptor (type 3) antagonist

1 reference

12 December 2020

Effect of tegaserod on esophageal pain threshold, regurgitation, and symptom relief in patients with functional heartburn and mechanical sensitivity

1 reference

12 December 2020

Distribution of mRNA coding for 5-hydroxytryptamine receptor subtypes in the intestines of healthy dairy cows and dairy cows with cecal dilatation-dislocation

1 reference

12 December 2020

Regulation of the peristaltic reflex by peptides of the myenteric plexus

1 reference

12 December 2020

Review article: the complexity of drug development for irritable bowel syndrome

1 reference

12 December 2020

Review article: intestinal serotonin signalling in irritable bowel syndrome

1 reference

12 December 2020

Detection of the 5-HT1A receptor and 5-HT1A receptor mRNA in the rat bowel and pancreas: comparison with 5-HT1P receptors

1 reference

12 December 2020

5-HT4 receptors located on cholinergic nerves in human colon circular muscle

1 reference

12 December 2020

5-HT(2B) receptors play a key role in mediating the excitatory effects of 5-HT in human colon in vitro

1 reference

12 December 2020

Comparison of tegaserod (HTF 919) and its main human metabolite with cisapride and erythromycin on cardiac repolarization in the isolated rabbit heart

1 reference

12 December 2020

Cloning and expression of a 5-hydroxytryptamine7 receptor positively coupled to adenylyl cyclase

1 reference

12 December 2020

Human colonic mucosa possesses a mixed population of 5-HT receptors

1 reference

12 December 2020

Mechanism of the anti-emetic activity of 5-HT3 receptor antagonists

1 reference

12 December 2020

A review of central 5-HT receptors and their function

1 reference

12 December 2020

Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome.

1 reference

12 December 2020

Effects of venlafaxine, buspirone, and placebo on colonic sensorimotor functions in healthy humans

1 reference

12 December 2020

Review article: serotonin receptors and transporters -- roles in normal and abnormal gastrointestinal motility

1 reference

12 December 2020

Heterogeneity of 5-HT receptors mediating secretion in the human intestine

1 reference

12 December 2020

Novel brain-specific 5-HT4 receptor splice variants show marked constitutive activity: role of the C-terminal intracellular domain

1 reference

12 December 2020

Signalling mechanism coupled to 5‐hydroxytryptamine4 receptor‐mediated facilitation of fast synaptic transmission in the guinea‐pig ileum myenteric plexus

1 reference

12 December 2020

Characterization and localization of a peripheral neural 5-hydroxytryptamine receptor subtype (5-HT1P) with a selective agonist, 3H-5-hydroxyindalpine

1 reference

12 December 2020

Serotonin induces Cl- secretion in human jejunal mucosa in vitro via a nonneural pathway at a 5-HT4 receptor

1 reference

12 December 2020

Serotonin: a mediator of the brain-gut connection

1 reference

12 December 2020

Serotonin uptake and its modulation in rat jejunal enterocyte preparation

1 reference

12 December 2020

Increased platelet depleted plasma 5-hydroxytryptamine concentration following meal ingestion in symptomatic female subjects with diarrhoea predominant irritable bowel syndrome

1 reference

12 December 2020

Electrophysiological studies of 5-hydroxytryptamine receptors on enteric neurons

1 reference

12 December 2020

Influence of sumatriptan on gastric fundus tone and on the perception of gastric distension in man

1 reference

12 December 2020

Association between a functional polymorphism in the serotonin transporter gene and diarrhoea predominant irritable bowel syndrome in women

1 reference

12 December 2020

The terminals of myenteric intrinsic primary afferent neurons of the guinea-pig ileum are excited by 5-hydroxytryptamine acting at 5-hydroxytryptamine-3 receptors

1 reference

12 December 2020

Alosetron and irritable bowel syndrome

1 reference

12 December 2020

Alignment of receptor nomenclature with the human genome: classification of 5-HT1B and 5-HT1D receptor subtypes.

1 reference

12 December 2020

Activation of 5-HT1P receptors on submucosal afferents subsequently triggers VIP neurons and chloride secretion in the guinea-pig colon

1 reference

12 December 2020

Effect of amitriptyline on symptoms, sleep, and visceral perception in patients with functional dyspepsia

1 reference

12 December 2020

Lisuride, a dopamine receptor agonist with 5-HT2B receptor antagonist properties: absence of cardiac valvulopathy adverse drug reaction reports supports the concept of a crucial role for 5-HT2B receptor agonism in cardiac valvular fibrosis

1 reference

12 December 2020

The selective serotonin reuptake inhibitor fluoxetine does not change rectal sensitivity and symptoms in patients with irritable bowel syndrome: a double blind, randomized, placebo-controlled study

1 reference

12 December 2020

Characterization of human 5-HT4(d) receptor desensitization in CHO cells

1 reference

12 December 2020

Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E.

1 reference

12 December 2020

5-HT7 receptors modulate peristalsis and accommodation in the guinea pig ileum.

1 reference

12 December 2020

5-Hydroxytryptamine (5-HT)-induced endothelium-dependent relaxation of pig coronary arteries is mediated by 5-HT receptors similar to the 5-HT1D receptor subtype

1 reference

12 December 2020

Vagal control of the heart: central serotonergic (5-HT) mechanisms

1 reference

12 December 2020

Review article: the therapeutic potential of 5-HT3 receptor antagonists in the treatment of irritable bowel syndrome

1 reference

12 December 2020

The effects of vagal nerve stimulation on endoluminal release of serotonin and substance P into the feline small intestine

1 reference

12 December 2020

Characterization of 5-hydroxytryptamine (5-HT) receptor subtypes influencing colonic motility in conscious dogs

1 reference

12 December 2020

Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor

1 reference

12 December 2020

Cisapride stimulates motility of the intestine via the 5-hydroxytryptamine receptors

1 reference

12 December 2020

Expression of 5-HT3 receptors in the rat gastrointestinal tract

1 reference

12 December 2020

Characterisation of 5-HT receptors in human coronary arteries by molecular and pharmacological techniques

1 reference

12 December 2020

Drug evaluation: Pumosetrag for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.

1 reference

12 December 2020

Effect of the 5HT1A receptor partial agonist buspirone on colorectal distension-induced pseudoaffective and behavioral responses in the female Wistar rat.

1 reference

12 December 2020

Cloning of the human serotonin 5-HT2 and 5-HT1C receptor subtypes

1 reference

12 December 2020

Molecular and pharmacological characterization of serotonin 5-HT2A and 5-HT2B receptor subtypes in dog

1 reference

12 December 2020

Differences in signal transduction of two 5-HT4 receptor splice variants: compound specificity and dual coupling with Galphas- and Galphai/o-proteins

1 reference

12 December 2020

Effect of a novel prokinetic drug, R093877, on gastrointestinal transit in healthy volunteers

1 reference

12 December 2020

SB-207266: 5-HT4 receptor antagonism in human isolated gut and prevention of 5-HT-evoked sensitization of peristalsis and increased defaecation in animal models

1 reference

12 December 2020

Coexpression of 5-HT2A and 5-HT4 receptors coupled to distinct signaling pathways in human intestinal muscle cells

1 reference

12 December 2020

Activation of intrinsic afferent pathways in submucosal ganglia of the guinea pig small intestine

1 reference

12 December 2020

Review article: tegaserod for chronic constipation

1 reference

12 December 2020

5-HT7 receptors: current knowledge and future prospects

1 reference

12 December 2020

Activation of peripheral 5-HT receptors attenuates colonic sensitivity to intraluminal distension

1 reference

12 December 2020

Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1D alpha and 5-HT1D beta

1 reference

12 December 2020

Regulation of ion transport by 5-hydroxytryptamine in rat colon

1 reference

12 December 2020

Serotonin and the 5-HT(2B) receptor in the development of enteric neurons.

1 reference

12 December 2020

Incidence of ischemic colitis and serious complications of constipation among patients using alosetron: systematic review of clinical trials and post-marketing surveillance data

1 reference

12 December 2020

Altered 5-hydroxytryptamine signaling in patients with constipation- and diarrhea-predominant irritable bowel syndrome

1 reference

12 December 2020

The use of tegaserod in critically ill patients with impaired gastric motility.

1 reference

12 December 2020

Evidence for the involvement of 5-hydroxytryptamine 4 receptors in 5-hydroxytryptophan-induced diarrhea in mice

1 reference

12 December 2020

Effect of a novel 5-HT3 receptor agonist MKC-733 on upper gastrointestinal motility in humans.

1 reference

12 December 2020

Serotonin receptor mRNA expression in rat dorsal root ganglion neurons

1 reference

12 December 2020

Palonosetron: a unique 5-HT3 receptor antagonist indicated for the prevention of acute and delayed chemotherapy-induced nausea and vomiting.

1 reference

12 December 2020

Acute tryptophan depletion affects brain-gut responses in irritable bowel syndrome patients and controls.

1 reference

12 December 2020

Ligand-gated ion channels in the enteric nervous system

1 reference

12 December 2020

Sumatriptan, a selective 5-HT1 receptor agonist, induces a lag phase for gastric emptying of liquids in humans

1 reference

12 December 2020

Influence of 5-HT3 receptor antagonists in visceromotor and nociceptive responses to rectal distension before and during experimental colitis in rats

1 reference

12 December 2020

Spontaneous adverse event reports of serious ventricular arrhythmias, QT prolongation, syncope, and sudden death in patients treated with cisapride

1 reference

12 December 2020

Functional consequence of serotonin/5-HT2B receptor signaling in heart: role of mitochondria in transition between hypertrophy and heart failure?

1 reference

12 December 2020

Tegaserod for the treatment of irritable bowel syndrome

1 reference

12 December 2020

Cloning and characterization of a novel human 5-HT4 receptor variant that lacks the alternatively spliced carboxy terminal exon. RT-PCR distribution in human brain and periphery of multiple 5-HT4 receptor variants

1 reference

12 December 2020

Autoreceptors can modulate 5-hydroxytryptamine release from porcine and human small intestine in vitro

1 reference

12 December 2020

Treatment of chronic constipation with cisapride and placebo

1 reference

12 December 2020

Understanding the pathobiology of chemotherapy-induced nausea and vomiting. Providing a basis for therapeutic progress

1 reference

12 December 2020

Abnormalities of 5-hydroxytryptamine metabolism in irritable bowel syndrome

1 reference

12 December 2020

5-Hydroxytryptamine receptor subtype messenger RNAs in rat peripheral sensory and sympathetic ganglia: a polymerase chain reaction study

1 reference

12 December 2020

Compounds possessing 5-HT3 receptor antagonistic activity inhibit intestinal propulsion in mice

1 reference

12 December 2020

Dual role of 5-HT3 receptors in a rat model of delayed stress-induced visceral hyperalgesia.

1 reference

12 December 2020

Delayed gastric emptying: whom to test, how to test, and what to do

1 reference

12 December 2020

Cisapride in the management of chronic functional dyspepsia: a multicenter, double-blind, placebo-controlled study

1 reference

12 December 2020

Pharmacological characterization of a novel 5-HT4 receptor agonist, TS-951, in vitro

1 reference

12 December 2020

Tegaserod, a 5-HT4 receptor partial agonist, accelerates gastric emptying and gastrointestinal transit in healthy male subjects

1 reference

12 December 2020

Characterization of a postjunctional 5-HT receptor mediating relaxation of guinea-pig isolated ileum

1 reference

12 December 2020

Cilansetron: a new serotonergic agent for the irritable bowel syndrome with diarrhoea

1 reference

12 December 2020

Review article: current and emerging therapies for functional dyspepsia

1 reference

12 December 2020

Role of 5-HT1B/D receptors in canine gastric accommodation: effect of sumatriptan and 5-HT1B/D receptor antagonists

1 reference

12 December 2020

Differential functional effects of two 5-HT4 receptor isoforms in adult cardiomyocytes.

1 reference

12 December 2020

Desperately seeking serotonin... A commentary on the withdrawal of tegaserod and the state of drug development for functional and motility disorders

1 reference

12 December 2020

Review article: The role of serotonergic agents in the treatment of patients with primary chronic constipation

1 reference

12 December 2020

MDL 72832: a potent and stereoselective ligand at central and peripheral 5-HT1A receptors

1 reference

12 December 2020

Granisetron and ondansetron: effects on the ileal brake mechanism in the rat

1 reference

12 December 2020

5-HT6 receptors: a novel target for cognitive enhancement

1 reference

12 December 2020

Molecular cloning, functional expression, and mRNA tissue distribution of the human 5-hydroxytryptamine2B receptor

1 reference

12 December 2020

Effect of renzapride on transit in constipation-predominant irritable bowel syndrome

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12 December 2020

Pharmacological characterization of 5-hydroxytryptamine-induced motor activity (in vitro) in the guinea pig gastric antrum and corpus

1 reference

12 December 2020

Antidepressants in IBS: are we deluding ourselves?

1 reference

12 December 2020

Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype

1 reference

12 December 2020

Multiple mechanisms of fast excitatory synaptic transmission in the enteric nervous system

1 reference

12 December 2020

Update on the role of drug therapy in non-ulcer dyspepsia.

1 reference

12 December 2020

Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract

1 reference

12 December 2020

Occurrence of colon ischemia in relation to irritable bowel syndrome

1 reference

12 December 2020

Effects of the enterokinetic prucalopride (R093877) on colonic motility in fasted dogs

1 reference

12 December 2020

Rationale for using serotonergic agents to treat irritable bowel syndrome.

1 reference

12 December 2020

Quantitative mRNA analysis of five C-terminal splice variants of the human 5-HT4 receptor in the central nervous system by TaqMan real time RT-PCR.

1 reference

12 December 2020

The involvement of 5-HT3 and 5-HT4 receptors in two models of gastrointestinal transit in mice

1 reference

12 December 2020

The 5-HT4 receptor: molecular cloning and pharmacological characterization of two splice variants

1 reference

12 December 2020

American Gastroenterological Association technical review on the diagnosis and treatment of gastroparesis

1 reference

12 December 2020

Prucalopride is effective in patients with severe chronic constipation in whom laxatives fail to provide adequate relief. Results of a double-blind, placebo-controlled clinical trial

1 reference

12 December 2020

The serotonin signaling system: from basic understanding to drug development for functional GI disorders

1 reference

12 December 2020

Effect of MKC-733, a 5-HT receptor partial agonist, on bowel motility and symptoms in subjects with constipation: an exploratory study

1 reference

12 December 2020

Condition-specific deactivation of brain regions by 5-HT3 receptor antagonist Alosetron

1 reference

12 December 2020

Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome

1 reference

12 December 2020

Influence of citalopram, a selective serotonin reuptake inhibitor, on oesophageal hypersensitivity: a double-blind, placebo-controlled study

1 reference

12 December 2020

Regional differences in expression of TPH-1, SERT, 5-HT(3) and 5-HT(4) receptors in the human stomach and duodenum

1 reference

12 December 2020

Effects of 5-HT(3) antagonism on postprandial gastric volume and symptoms in humans

1 reference

12 December 2020

The effects of tegaserod (HTF 919) on oesophageal acid exposure in gastro-oesophageal reflux disease.

1 reference

12 December 2020

Role of nitric oxide in fasting gastric fundus tone and in 5-HT1 receptor-mediated relaxation of gastric fundus.

1 reference

12 December 2020

5-HT4 receptor agonists enhance both cholinergic and nitrergic activities in human isolated colon circular muscle

1 reference

12 December 2020

Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase

1 reference

12 December 2020

Tegaserod accelerates orocecal transit in patients with constipation-predominant irritable bowel syndrome

1 reference

12 December 2020

Inter-digestive and post-prandial antro-pyloro-duodenal motor activity in humans: effect of 5-hydroxytryptamine 1 receptor agonism

1 reference

12 December 2020

Interactions of serotonin with multiple receptors and neurotransmitters in the guinea-pig isolated colon.

1 reference

12 December 2020

5-HT (serotonin) physiology and related drugs.

1 reference

12 December 2020

Effect of the selective serotonin reuptake inhibitor sertraline on gastric sensitivity and compliance in healthy humans

1 reference

12 December 2020

Effect of ondansetron on Salmonella typhimurium-induced net fluid accumulation in the pig jejunum in vivo.

1 reference

12 December 2020

Effects of the selective serotonin reuptake inhibitor, fluoxetine, on regional gastric contractility

1 reference

12 December 2020

Review article: cardiac adverse effects of gastrointestinal prokinetics

1 reference

12 December 2020

5-Hydroxytryptamine(7) receptor activation decreases slow afterhyperpolarization amplitude in CA3 hippocampal pyramidal cells

1 reference

12 December 2020

Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel

1 reference

12 December 2020

Functional bowel disorders

1 reference

12 December 2020

Effects of serotonin transporter inhibition on gastrointestinal motility and colonic sensitivity in the mouse

1 reference

12 December 2020

Ultrastructural examination of the targets of serotoninn immunoreactive descending interneurons in the guinea pig small intestine

1 reference

12 December 2020

Cloning and functional characterization of the rat stomach fundus serotonin receptor

1 reference

12 December 2020

Efficacy of cisapride and domperidone in functional (nonulcer) dyspepsia: a meta-analysis

1 reference

12 December 2020

Selective effects of serotonergic psychoactive agents on gastrointestinal functions in health

1 reference

12 December 2020

Idiopathic gastroparesis

1 reference

12 December 2020

Alosetron, a 5-HT3 receptor antagonist, delays colonic transit in patients with irritable bowel syndrome and healthy volunteers

1 reference

12 December 2020

1 reference

12 December 2020

Propulsion in guinea pig colon induced by 5-hydroxytryptamine (HT) via 5-HT4 and 5-HT3 receptors.

1 reference

12 December 2020

5-HT1A and 5-HT4 receptors mediate inhibition and facilitation of fast synaptic transmission in enteric neurons

1 reference

12 December 2020

1 reference

12 December 2020

Serotonergic facilitation of synaptic activity in the developing rat prefrontal cortex

1 reference

12 December 2020

Nerves, reflexes, and the enteric nervous system: pathogenesis of the irritable bowel syndrome

1 reference

12 December 2020

Stimulant effects of 5-hydroxytryptamine on guinea pig stomach preparations in vitro.

1 reference

12 December 2020

Comparison of 5-HT4 and 5-HT7 receptor expression and function in the circular muscle of the human colon

1 reference

12 December 2020

Characterization of the contraction to 5-HT in the canine colon longitudinal muscle

1 reference

12 December 2020

5-HT(3) and histamine H(1) receptors mediate afferent nerve sensitivity to intestinal anaphylaxis in rats

1 reference

12 December 2020

10.1007/S00210-008-0276-9

Identifiers

DOI

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18 August 2017

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