(Q37140645)

18 August 2017

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title

AAV vectors for RNA-based modulation of gene expression (English)

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18 August 2017

O Danos

1

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18 August 2017

publication date

17 April 2008

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18 August 2017

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18 August 2017

volume

15

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18 August 2017

issue

11

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18 August 2017

page(s)

864-869

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Role of plasmid-coded RNA and ribonuclease III in plasmid DNA replication

18 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Nuclear antisense RNA induces extensive adenosine modifications and nuclear retention of target transcripts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Gene silencing in mammals by small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Ribozyme gene therapy: applications for molecular medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

The spliceosome: a novel multi-faceted target for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Spliceosome-mediated RNA trans-splicing as a tool for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Strategies for silencing human disease using RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: the retina as a model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Lessons from Nature: microRNA-based shRNA libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Titers of HIV-based vectors encoding shRNAs are reduced by a dicer-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Development of hammerhead ribozymes to modulate endogenous gene expression for functional studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Stable alteration of pre-mRNA splicing patterns by modified U7 small nuclear RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Chimeric adeno-associated virus/antisense U1 small nuclear RNA effectively rescues dystrophin synthesis and muscle function by local treatment of mdx mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Regulation of gene expression in vivo following transduction by two separate rAAV vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Comparison of RNAi efficiency mediated by tetracycline-responsive H1 and U6 promoter variants in mammalian cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Time-dependent reorganization of brain circuitry underlying long-term memory storage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

In vivo transduction of cerebellar Purkinje cells using adeno-associated virus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

VEGF links hippocampal activity with neurogenesis, learning and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

In vivo inhibition of hippocampal Ca2+/calmodulin-dependent protein kinase II by RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

rAAV-mediated shRNA ameliorated neuropathology in Huntington disease model mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Local gene knockdown in the brain using viral-mediated RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Down-regulation of alpha-synuclein expression can rescue dopaminergic cells from cell death in the substantia nigra of Parkinson's disease rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Therapeutic liabilities of in vivo viral vector tropism: adeno-associated virus vectors, NMDAR1 antisense, and focal seizure sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Ribozyme rescue of photoreceptor cells in P23H transgenic rats: long-term survival and late-stage therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Preservation of photoreceptor morphology and function in P23H rats using an allele independent ribozyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

RNA interference-mediated suppression and replacement of human rhodopsin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Anti-clarin-1 AAV-delivered ribozyme induced apoptosis in the mouse cochlea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Ribozyme knockdown of the gamma-subunit of rod cGMP phosphodiesterase alters the ERG and retinal morphology in wild-type mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Suppression of mitochondrial oxidative stress provides long-term neuroprotection in experimental optic neuritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

SOD2 knockdown mouse model of early AMD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Rapid and stable knockdown of an endogenous gene in retinal pigment epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

AAV-mediated knockdown of phospholamban leads to improved contractility and calcium handling in cardiomyocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Rescue of dystrophic muscle through U7 snRNA-mediated exon skipping

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Gene expression profiling to monitor therapeutic and adverse effects of antisense therapies for Duchenne muscular dystrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Body-wide gene therapy of Duchenne muscular dystrophy in the mdx mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

AAV mediated expression of anti-sense neuropeptide Y cRNA in the arcuate nucleus of rats results in decreased weight gain and food intake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Leptin receptor signaling in midbrain dopamine neurons regulates feeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Attenuation of hypertension and heart hypertrophy by adeno-associated virus delivering angiotensinogen antisense

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

AAV delivery of mineralocorticoid receptor shRNA prevents progression of cold-induced hypertension and attenuates renal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Long-term inhibition of the central alpha(2B)-adrenergic receptor gene via recombinant AAV-delivered antisense in hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Spliceosome-mediated RNA trans-splicing with recombinant adeno-associated virus partially restores cystic fibrosis transmembrane conductance regulator function to polarized human cystic fibrosis airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Preferential silencing of a common dominant rhodopsin mutation does not inhibit retinal degeneration in a transgenic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

Inhibition of thymidine kinase gene expression by anti-sense RNA: A molecular approach to genetic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

7 January 2021

Strategems in vitro for gene therapies directed to dominant mutations

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

7 January 2021

Local dystrophin restoration with antisense oligonucleotide PRO051

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

7 January 2021

RNAi inhibition of mineralocorticoid receptors prevents the development of cold-induced hypertension

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.69

7 January 2021

Identifiers

DOI

10.1038/GT.2008.69

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18 August 2017

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