(Q37171562)

18 August 2017

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title

Covalent inhibitors of glycosidases and their applications in biochemistry and biology (English)

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18 August 2017

Brian P Rempel

1

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18 August 2017

Stephen G Withers

series ordinal

2

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18 August 2017

language of work or name

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22 May 2008

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18 August 2017

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18 August 2017

volume

18

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18 August 2017

issue

8

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18 August 2017

page(s)

570-586

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Glycosidase inhibitors: update and perspectives on practical use.

18 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Naturally occurring iminosugars and related compounds: structure, distribution, and biological activity

21 January 2018

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Inhibition of glucocerebrosidase and induction of neural abnormality by cyclophellitol in mice.

21 January 2018

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Accumulation of tissue glucosylsphingosine in Gaucher-like mouse induced by the glucosylceramidase inhibitor cyclophellitol.

21 January 2018

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Suicide-substrate inactivation of beta-galactosidase by diazomethyl beta-D-galactopyranosyl ketone.

21 January 2018

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Rapid screening of the aglycone specificity of glycosidases: applications to enzymatic synthesis of oligosaccharides

21 January 2018

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Phosphatidylcholine synthesis is elevated in neuronal models of Gaucher disease due to direct activation of CTP:phosphocholine cytidylyltransferase by glucosylceramide

21 January 2018

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Identification of the non-lysosomal glucosylceramidase as beta-glucosidase 2

21 January 2018

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Stereospecific ring opening of conduritol-B-epoxide by an active site aspartate residue of sucrase-isomaltase

21 January 2018

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Crystal structures of complexes of N-butyl- and N-nonyl-deoxynojirimycin bound to acid beta-glucosidase: insights into the mechanism of chemical chaperone action in Gaucher disease

21 January 2018

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High resolution X-ray crystallography shows that ascorbate is a cofactor for myrosinase and substitutes for the function of the catalytic base

21 January 2018

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Therapeutic applications of imino sugars in lysosomal storage disorders

21 January 2018

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Identification of the two essential groups in the family 3 beta-glucosidase from Flavobacterium meningosepticum by labelling and tandem mass spectrometric analysis

21 January 2018

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Mapping the conformational itinerary of beta-glycosidases by X-ray crystallography

21 January 2018

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Recent structural insights into the expanding world of carbohydrate-active enzymes

21 January 2018

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Altered intracellular redox status in Gaucher disease fibroblasts and impairment of adaptive response against oxidative stress

21 January 2018

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Human acid beta-glucosidase: isolation and amino acid sequence of a peptide containing the catalytic site

21 January 2018

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X-ray structure of human acid-β-glucosidase, the defective enzyme in Gaucher disease

21 January 2018

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Murine models of acute neuronopathic Gaucher disease

21 January 2018

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Identification of candidate active site residues in lysosomal beta-hexosaminidase A.

21 January 2018

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A novel alpha-glucosidase from the acidophilic archaeon Ferroplasma acidiphilum strain Y with high transglycosylation activity and an unusual catalytic nucleophile

21 January 2018

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Structural basis for cyclophellitol inhibition of a beta-glucosidase

21 January 2018

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Glycosidase inhibition: an assessment of the binding of 18 putative transition-state mimics

21 January 2018

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Inhibition of glycosylation processing alters the growth parameters of cells transformed by the oncogene of simian sarcoma virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Active-site peptide "fingerprinting" of glycosidases in complex mixtures by mass spectrometry. Discovery of a novel retaining beta-1,4-glycanase in Cellulomonas fimi

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

New families in the classification of glycosyl hydrolases based on amino acid sequence similarities

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Epidermal sphingolipids: metabolism, function, and roles in skin disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Studies on the transglucosylation reactions of cassava and Thai rosewood beta-glucosidases using 2-deoxy-2-fluoro-glycosyl-enzyme intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

A mechanism-based affinity-labeling agent for possible use in isolating N-acetylglucosaminidase

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

21 January 2018

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Molecular and active-site structure of a Bacillus 1,3-1,4-beta-glucanase

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Investigation of the active site of the extracellular beta-D-xylosidase from Aspergillus carbonarius

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Crystallographic studies of the interaction of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 with natural substrates and products

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Elevation of intracellular glucosylceramide levels results in an increase in endoplasmic reticulum density and in functional calcium stores in cultured neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Investigation of the active site of Escherichia coli beta-D-galactosidase by photoaffinity labelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Efficient photoaffinity labeling of human beta-hexosaminidase A. Synthesis and application of 3-azi-1-[(2-acetamido-2-deoxy-1-beta- D-glucopyranosyl)thio]- and -galactopyranosyl)thio]butane

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Mechanism-based fluorescent labeling of beta-galactosidases. An efficient method in proteomics for glycoside hydrolases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Inversion of the roles of the nucleophile and acid/base catalysts in the covalent binding of epoxyalkyl xyloside inhibitor to the catalytic glutamates of endo-1,4-beta-xylanase (XYNII): a molecular dynamics study

21 January 2018

1 reference

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Epoxyalkyl oligo-(1→4)-β-D-glucosides as active-site-directed inhibitors of cellulases

21 January 2018

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Amino acid sequence at the active site of beta-glucosidase A from bitter almonds

21 January 2018

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Crystallographic structure of human beta-hexosaminidase A: interpretation of Tay-Sachs mutations and loss of GM2 ganglioside hydrolysis

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease

21 January 2018

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Recent developments of transition-state analogue glycosidase inhibitors of non-natural product origin

21 January 2018

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Mice with type 2 and 3 Gaucher disease point mutations generated by a single insertion mutagenesis procedure

21 January 2018

1 reference

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Study of the preferred modification sites of the quinone methide intermediate resulting from the latent trapping device of the activity probes for hydrolases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Mechanistic and structural analysis of a family 31 alpha-glycosidase and its glycosyl-enzyme intermediate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Mutagenesis of glycosidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Identification of an essential glutamate residue in the active site of endoglucanase III from Trichoderma reesei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective mechanism-inspired inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Enzymatic hydrolysis of pyridoxine-5'-beta-D-glucoside is catalyzed by intestinal lactase-phlorizin hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Crystal structure of human beta-hexosaminidase B: understanding the molecular basis of Sandhoff and Tay-Sachs disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Crystallographic evidence for substrate-assisted catalysis in a bacterial beta-hexosaminidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Demonstration of feasibility of in vivo gene therapy for Gaucher disease using a chemically induced mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

In vivo inhibition of beta-glucosidase and beta-mannosidase activity in rats by 2-deoxy-2-fluoro-beta-glycosyl fluorides and recovery of activity in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

ERAD: the long road to destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Elevation of glucosylceramide in multidrug-resistant cancer cells and accumulation in cytoplasmic droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Insights into the mechanism of Drosophila melanogaster Golgi alpha-mannosidase II through the structural analysis of covalent reaction intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

X-ray structure of human acid-beta-glucosidase covalently bound to conduritol-B-epoxide. Implications for Gaucher disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Structure-function relationships in glucosidase I: amino acids involved in binding the substrate to the enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Synthesis of a novel photoaffinity derivative of 1-deoxynojirimycin for active site-directed labeling of glucosidase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

21 January 2018

Glycosidase mechanisms

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Therapeutic strategies to ameliorate lysosomal storage disorders--a focus on Gaucher disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Correlation between enzyme activity and substrate storage in a cell culture model system for Gaucher disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

A regulatory role for sphingolipids in neuronal growth. Inhibition of sphingolipid synthesis and degradation have opposite effects on axonal branching.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Facile synthesis toward the construction of an activity probe library for glycosidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Generation of a conditional knockout of murine glucocerebrosidase: utility for the study of Gaucher disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

The Gaucher mouse: differential action of conduritol B epoxide and reversibility of its effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

The Gaucher mouse: additional biochemical alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Gaucher disease mouse models: point mutations at the acid beta-glucosidase locus combined with low-level prosaposin expression lead to disease variants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Protein engineering in the alpha-amylase family: catalytic mechanism, substrate specificity, and stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Phosphatidylcholine metabolism is altered in a monocyte-derived macrophage model of Gaucher disease but not in lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Design and synthesis of activity probes for glycosidases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

A mass spectrometry-based approach for probing enzyme active sites: identification of Glu 127 in Cellulomonas fimi exoglycanase as the residue modified by N-bromoacetyl cellobiosylamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

21 January 2018

Glycosidase mechanisms

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Photoaffinity labeling and its application in structural biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Synthesis and testing of mechanism-based protein-profiling probes for retaining endo-glycosidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Cyclophellitol: a naturally occurring mechanism-based inactivator of beta-glucosidases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Viable mouse models of acid beta-glucosidase deficiency: the defect in Gaucher disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Breakdown of oligosaccharides by the process of elimination

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Intestinal lactase-phlorizin hydrolase (LPH): the two catalytic sites; the role of the pancreas in pro-LPH maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Synthesis and testing of 2-deoxy-2,2-dihaloglycosides as mechanism-based inhibitors of alpha-glycosidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Gaucher disease: Perspectives on a prototype lysosomal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Salicortin: a repeat-attack new-mechanism-based Agrobacterium faecalis beta-glucosidase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

Structural comparison of differently glycosylated forms of acid-β-glucosidase, the defective enzyme in Gaucher disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWN041

A strategy for functional proteomic analysis of glycosidase activity from cell lysates.

21 January 2018

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1002/ANIE.200454235

Production, isolation and structure determination of a novel beta-glucosidase inhibitor, cyclophellitol, from Phellinus sp

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.43.49

Identifiers

DOI

10.1093/GLYCOB/CWN041

1 reference

18 August 2017

1 reference