(Q37194949)

18 August 2017

p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells (English)

1 reference

18 August 2017

David H Raulet

5

0 references

author name string

Alexandre Iannello

1

1 reference

18 August 2017

Thornton W Thompson

2

1 reference

18 August 2017

Michele Ardolino

3

1 reference

18 August 2017

Scott W Lowe

4

1 reference

18 August 2017

language of work or name

English

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publication date

16 September 2013

1 reference

Journal of Experimental Medicine

18 August 2017

1 reference

18 August 2017

210

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18 August 2017

2057-2069

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18 August 2017

10

1 reference

describes a project that uses

18 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3782044/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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6 September 2017

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RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry

6 September 2017

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p53 is an important regulator of CCL2 gene expression

6 September 2017

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Granule exocytosis mediates immune surveillance of senescent cells.

6 September 2017

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Comprehensive analysis of NKG2D ligand expression and release in leukemia: implications for NKG2D-mediated NK cell responses.

6 September 2017

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Expression of the RAE-1 family of stimulatory NK-cell ligands requires activation of the PI3K pathway during viral infection and transformation

6 September 2017

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Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2.

6 September 2017

1 reference

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Human NK cells are alerted to induction of p53 in cancer cells by upregulation of the NKG2D ligands ULBP1 and ULBP2.

6 September 2017

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Pro-senescence therapy for cancer treatment

6 September 2017

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G-protein-coupled receptors in control of natural killer cell migration

6 September 2017

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Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression

6 September 2017

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Four faces of cellular senescence.

6 September 2017

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Innate or adaptive immunity? The example of natural killer cells

6 September 2017

1 reference

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DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion

6 September 2017

1 reference

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Regulation of MCP-1 chemokine transcription by p53

6 September 2017

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Senescence in tumours: evidence from mice and humans

6 September 2017

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NKG2D ligand expression in human colorectal cancer reveals associations with prognosis and evidence for immunoediting

6 September 2017

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Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

6 September 2017

1 reference

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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

6 September 2017

1 reference

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Senescence of activated stellate cells limits liver fibrosis

6 September 2017

1 reference

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Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

6 September 2017

1 reference

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Chemokine signaling via the CXCR2 receptor reinforces senescence

6 September 2017

1 reference

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NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy

6 September 2017

1 reference

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The trafficking of natural killer cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Restoration of p53 function leads to tumour regression in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Oncogene-Induced Senescence: Putting the Brakes on Tumor Development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

BRAFE600-associated senescence-like cell cycle arrest of human naevi

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Roles of the NKG2D immunoreceptor and its ligands

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Expression and role of MICA and MICB in human hepatocellular carcinomas and their regulation by retinoic acid

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Epithelial-mesenchymal transition induced by senescent fibroblasts

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Regulatory T cells increase the avidity of primary CD8+ T cell responses and promote memory.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Oncogene-induced senescence as an initial barrier in lymphoma development

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3782044

3 September 2018

Identifiers

DOI

10.1084/JEM.20130783

1 reference

18 August 2017

1 reference

18 August 2017

1 reference