(Q37201951)

English

Long-term polyclonal and multilineage engraftment of methylguanine methyltransferase P140K gene-modified dog hematopoietic cells in primary and secondary recipients

scientific article published on 31 March 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Long-term polyclonal and multilineage engraftment of methylguanine methyltransferase P140K gene-modified dog hematopoietic cells in primary and secondary recipients (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Hans-Peter Kiem

8

object named as

Hans-Peter Kiem

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

author name string

Brian C Beard

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Reeteka Sud

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Kirsten A Keyser

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Christina Ironside

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Tobias Neff

5

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Sabine Gerull

6

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Grant D Trobridge

7

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

0 references

publication date

31 March 2009

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

113

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

21

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

5094-5103

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors

1 reference

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High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector

1 reference

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Insertional mutagenesis in gene therapy and stem cell biology

1 reference

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Stable differentiation and clonality of murine long-term hematopoiesis after extended reduced-intensity selection for MGMT P140K transgene expression

1 reference

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1 reference

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Foamy virus vector integration sites in normal human cells

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Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells

1 reference

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Chance or necessity? Insertional mutagenesis in gene therapy and its consequences

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Applied molecular evolution of O6-benzylguanine-resistant DNA alkyltransferases in human hematopoietic cells

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Protection and in vivo selection of hematopoietic stem cells using temozolomide, O6-benzylguanine, and an alkyltransferase-expressing retroviral vector

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Engineering human DNA alkyltransferases for gene therapy using random sequence mutagenesis.

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Retroviral transduction of a mutant methylguanine DNA methyltransferase gene into human CD34 cells confers resistance to O6-benzylguanine plus 1,3-bis(2-chloroethyl)-1-nitrosourea

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Novel human DNA alkyltransferases obtained by random substitution and genetic selection in bacteria

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Protection of bone marrow transplant recipients from lethal doses of methotrexate by the generation of methotrexate-resistant bone marrow

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The P140K mutant of human O(6)-methylguanine-DNA-methyltransferase (MGMT) confers resistance in vitro and in vivo to temozolomide in combination with the novel MGMT inactivator O(6)-(4-bromothenyl)guanine

1 reference

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14 September 2017

Overexpression of glutathione-S-transferase, MGSTII, confers resistance to busulfan and melphalan

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Methylguanine methyltransferase-mediated in vivo selection and chemoprotection of allogeneic stem cells in a large-animal model

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Hematopoietic stem cell compartment: acute and late effects of radiation therapy and chemotherapy

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Forced expression of cytidine deaminase confers resistance to cytosine arabinoside and gemcitabine

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Clonality analysis after retroviral-mediated gene transfer to CD34+ cells from the cord blood of ADA-deficient SCID neonates

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Selection for G156A O6-methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and protection from lethality in mice treated with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea.

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Synergistic efficacy of O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in a human colon cancer xenograft completely resistant to BCNU alone

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Differential effects of cytotoxic agents on hematopoietic progenitors

1 reference

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Increase in nitrosourea resistance in mammalian cells by retrovirally mediated gene transfer of bacterial O6-alkylguanine-DNA alkyltransferase

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Comparison of the inactivation of mammalian and bacterial O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine and O6-methylguanine

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Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1

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Nature of the hemopoietic stem cell compartment and its proliferative potential

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Reciprocal relationship between O6-methylguanine-DNA methyltransferase P140K expression level and chemoprotection of hematopoietic stem cells

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Hematopoietic stem cell deficit of transplanted bone marrow previously exposed to cytotoxic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/19336761

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retroviral-mediated gene transduction of human alkyltransferase complementary DNA confers nitrosourea resistance to human hematopoietic progenitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19336761

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retroviral vectors containing a variant dihydrofolate reductase gene for drug protection and in vivo selection of hematopoietic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19336761

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemangiosarcoma in dogs and cats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19336761

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multisystem stem cell failure after apparent recovery from alkylating agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/19336761

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1182/BLOOD-2008-09-176412

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

ResearchGate publication ID

0 references

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