(Q37216215)

English

Metabolic gene remodeling and mitochondrial dysfunction in failing right ventricular hypertrophy secondary to pulmonary arterial hypertension

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scholarly article

1 reference

Europe PubMed Central

19 August 2017

Metabolic gene remodeling and mitochondrial dysfunction in failing right ventricular hypertrophy secondary to pulmonary arterial hypertension (English)

1 reference

Europe PubMed Central

19 August 2017

arterial hypertension

0 references

right ventricular hypertrophy

1 reference

based on heuristic

inferred from title

Edward J Lesnefsky

14

object named as

Edward J Lesnefsky

1 reference

Europe PubMed Central

19 August 2017

Karol Szczepanek

3

object named as

Karol Szczepanek

1 reference

Europe PubMed Central

19 August 2017

author name string

Jose Gomez-Arroyo

1

1 reference

Europe PubMed Central

19 August 2017

Shiro Mizuno

2

1 reference

Europe PubMed Central

19 August 2017

Benjamin Van Tassell

4

1 reference

Europe PubMed Central

19 August 2017

Ramesh Natarajan

5

1 reference

Europe PubMed Central

19 August 2017

Cristobal G dos Remedios

6

1 reference

Europe PubMed Central

19 August 2017

Jennifer I Drake

7

1 reference

Europe PubMed Central

19 August 2017

Laszlo Farkas

8

1 reference

Europe PubMed Central

19 August 2017

Donatas Kraskauskas

9

1 reference

Europe PubMed Central

19 August 2017

Dayanjan S Wijesinghe

10

1 reference

Europe PubMed Central

19 August 2017

Charles E Chalfant

11

1 reference

Europe PubMed Central

19 August 2017

John Bigbee

12

1 reference

Europe PubMed Central

19 August 2017

Antonio Abbate

13

1 reference

Europe PubMed Central

19 August 2017

Harm J Bogaard

15

1 reference

Europe PubMed Central

19 August 2017

Norbert F Voelkel

16

1 reference

Europe PubMed Central

19 August 2017

publication date

14 November 2012

1 reference

Europe PubMed Central

19 August 2017

Circulation: Heart Failure

1 reference

Europe PubMed Central

19 August 2017

6

1 reference

Europe PubMed Central

19 August 2017

1

1 reference

Europe PubMed Central

19 August 2017

136-144

1 reference

Europe PubMed Central

19 August 2017

Pathobiology of pulmonary arterial hypertension and right ventricular failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

Molecular signature of a right heart failure program in chronic severe pulmonary hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

Mitochondrial adaptations to physiological vs. pathological cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

Defective DNA replication impairs mitochondrial biogenesis in human failing hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

A proposed mitochondrial-metabolic mechanism for initiation and maintenance of pulmonary arterial hypertension in fawn-hooded rats: the Warburg model of pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

The right ventricle under pressure: cellular and molecular mechanisms of right-heart failure in pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

Metabolic remodelling of the failing heart: beneficial or detrimental?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

The failing heart--an engine out of fuel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

Transcriptional regulatory circuits controlling mitochondrial biogenesis and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: a potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

Oxidative damage and mitochondrial decay in aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

6 September 2017

Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

14 September 2017

Targeting energetic metabolism: a new frontier in the pathogenesis and treatment of pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

26 June 2018

Staphylococcus aureus sepsis and mitochondrial accrual of the 8-oxoguanine DNA glycosylase DNA repair enzyme in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

26 June 2018

Progressive right ventricular dysfunction in patients with pulmonary arterial hypertension responding to therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

3 September 2018

Suppression of histone deacetylases worsens right ventricular dysfunction after pulmonary artery banding in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

3 September 2018

Adrenergic receptor blockade reverses right heart remodeling and dysfunction in pulmonary hypertensive rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

3 September 2018

The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

3 September 2018

A dynamic and chamber-specific mitochondrial remodeling in right ventricular hypertrophy can be therapeutically targeted

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

3 September 2018

Induction of mitochondrial biogenesis is a maladaptive mechanism in mitochondrial cardiomyopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

3 September 2018

The nuclear receptor ERRalpha is required for the bioenergetic and functional adaptation to cardiac pressure overload.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

3 September 2018

ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

3 September 2018

Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

3 September 2018

Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

3 September 2018

Microarray analysis reveals pivotal divergent mRNA expression profiles early in the development of either compensated ventricular hypertrophy or heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

3 September 2018

Survival in primary pulmonary hypertension. Validation of a prognostic equation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3790960

3 September 2018

Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23152488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

VEGF-R blockade causes endothelial cell apoptosis, expansion of surviving CD34+ precursor cells and transdifferentiation to smooth muscle-like and neuronal-like cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23152488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

1 reference

https://pubmed.ncbi.nlm.nih.gov/23152488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/23152488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of impaired fatty acid metabolism in right ventricular hypertrophy: assessment by I-123 beta-methyl iodophenyl pentadecanoic acid (BMIPP) myocardial single-photon emission computed tomography

1 reference

https://pubmed.ncbi.nlm.nih.gov/23152488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/CIRCHEARTFAILURE.111.966127

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

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