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Role of non-degradative ubiquitination in interleukin-1 and toll-like receptor signaling.
scientific article published on 06 August 2008
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Europe PubMed Central
PMCID
2659176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
review article
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Europe PubMed Central
title
Role of non-degradative ubiquitination in interleukin-1 and toll-like receptor signaling
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2659176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
main subject
toll-like receptor
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interleukins
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protein ubiquitination
1 reference
based on heuristic
inferred from title
author
Andrew G Bowie
series ordinal
2
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stated in
Europe PubMed Central
PMCID
2659176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
author name string
Sinéad E Keating
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2659176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
language of work or name
English
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publication date
6 August 2008
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stated in
Europe PubMed Central
PMCID
2659176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
published in
Journal of Biological Chemistry
1 reference
stated in
Europe PubMed Central
PMCID
2659176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
volume
284
1 reference
stated in
Europe PubMed Central
PMCID
2659176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
issue
13
1 reference
stated in
Europe PubMed Central
PMCID
2659176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
page(s)
8211-8215
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Europe PubMed Central
PMCID
2659176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
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Deubiquitylation and regulation of the immune response
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PubMed Central
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Are the IKKs and IKK-related kinases TBK1 and IKK-epsilon similarly activated?
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9 September 2017
Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation
1 reference
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9 September 2017
Pellino 3b negatively regulates interleukin-1-induced TAK1-dependent NF kappaB activation
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9 September 2017
Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase
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PubMed Central
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9 September 2017
DUBA: a deubiquitinase that regulates type I interferon production
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IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination
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9 September 2017
The interplay between viruses and innate immune signaling: recent insights and therapeutic opportunities
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Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKepsilon-dependent Lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF.
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9 September 2017
Kinase-active interleukin-1 receptor-associated kinases promote polyubiquitination and degradation of the Pellino family: direct evidence for PELLINO proteins being ubiquitin-protein isopeptide ligases
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Toll-like receptors, RIG-I-like RNA helicases and the antiviral innate immune response
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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
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9 September 2017
Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses
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9 September 2017
Pellino proteins are more than scaffold proteins in TLR/IL-1R signalling: a role as novel RING E3-ubiquitin-ligases
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9 September 2017
Toll-like receptors and RNA helicases: two parallel ways to trigger antiviral responses
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9 September 2017
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]
1 reference
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PubMed Central
reference URL
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9 September 2017
Pathogen recognition and innate immunity
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9 September 2017
IL-1 receptor-associated kinase 1 is critical for latent membrane protein 1-induced p65/RelA serine 536 phosphorylation and NF-kappaB activation
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9 September 2017
Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
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9 September 2017
Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
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9 September 2017
Ubiquitin signalling in the NF-kappaB pathway
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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9 September 2017
The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO
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PubMed Central
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9 September 2017
Polyubiquitin chains: polymeric protein signals
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PubMed Central
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9 September 2017
IRAK1 serves as a novel regulator essential for lipopolysaccharide-induced interleukin-10 gene expression
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9 September 2017
Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
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PubMed Central
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9 September 2017
TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains
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PubMed Central
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9 September 2017
The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes
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PubMed Central
reference URL
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9 September 2017
RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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9 September 2017
Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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9 September 2017
A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
retrieved
9 September 2017
Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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9 September 2017
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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9 September 2017
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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9 September 2017
The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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9 September 2017
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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9 September 2017
The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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14 September 2017
YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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14 September 2017
Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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14 September 2017
The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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26 June 2018
Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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26 June 2018
Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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3 September 2018
Identification of TRAF6-dependent NEMO polyubiquitination sites through analysis of a new NEMO mutation causing incontinentia pigmenti.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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3 September 2018
Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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3 September 2018
The role of ubiquitination in Drosophila innate immunity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659176
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3 September 2018
Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.R800038200
retrieved
21 January 2018
The interleukin-1 receptor-associated kinase is degraded by proteasomes following its phosphorylation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18684710
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1074/JBC.R800038200
1 reference
stated in
Europe PubMed Central
PMCID
2659176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
PMCID
2659176
1 reference
stated in
Europe PubMed Central
PMCID
2659176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
PubMed ID
18684710
1 reference
stated in
Europe PubMed Central
PMCID
2659176
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
ResearchGate publication ID
23153658
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