(Q52659693)

5 May 2018

title

The role of ubiquitination in Drosophila innate immunity. (English)

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5 May 2018

main subject

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Immune deficiency Dmel_CG5576

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Fas-associated death domain Dmel_CG12297

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TGF-beta activated kinase 1 Dmel_CG18492

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Bendless Dmel_CG18319

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protein ubiquitination

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2

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5 May 2018

Tom Maniatis

7

object named as

Tom Maniatis

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5 May 2018

Rui Zhou

1

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5 May 2018

Mei Hong

3

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5 May 2018

Dorothy S Liao

4

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5 May 2018

Yvonne Chung

5

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5 May 2018

Zhijian J Chen

6

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5 May 2018

language of work or name

English

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publication date

4 August 2005

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5 May 2018

Journal of Biological Chemistry

published in

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5 May 2018

volume

280

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5 May 2018

issue

40

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5 May 2018

page(s)

34048-34055

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5 May 2018

The immune response of Drosophila

cites work

1 reference

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A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense

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The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

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Requirement for a peptidoglycan recognition protein (PGRP) in Relish activation and antibacterial immune responses in Drosophila

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The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein

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The Drosophila immune system detects bacteria through specific peptidoglycan recognition

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Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway

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Drosophila peptidoglycan recognition protein LC (PGRP-LC) acts as a signal-transducing innate immune receptor

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Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses

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Immune Activation of NF-κB and JNK Requires Drosophila TAK1

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21 January 2018

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Caspase-mediated processing of the Drosophila NF-kappaB factor Relish

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A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity

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The antibacterial arm of the drosophila innate immune response requires an IkappaB kinase.

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Role of Drosophila IKK gamma in a toll-independent antibacterial immune response

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Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

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TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

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TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

21 January 2018

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Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling

21 January 2018

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An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

21 January 2018

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Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

21 January 2018

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The Drosophila bendless gene encodes a neural protein related to ubiquitin-conjugating enzymes

21 January 2018

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Treatment of l(2)mbn Drosophila tumorous blood cells with the steroid hormone ecdysone amplifies the inducibility of antimicrobial peptide gene expression

21 January 2018

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Inducible expression of double-stranded RNA reveals a role for dFADD in the regulation of the antibacterial response in Drosophila adults

21 January 2018

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The Drosophila immune defense against gram-negative infection requires the death protein dFADD.

21 January 2018

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The Drosophila caspase Dredd is required to resist gram-negative bacterial infection

21 January 2018

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dFADD, a novel death domain-containing adapter protein for the Drosophila caspase DREDD.

21 January 2018

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Sequential activation of signaling pathways during innate immune responses in Drosophila.

21 January 2018

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Targeting of TAK1 by the NF-kappa B protein Relish regulates the JNK-mediated immune response in Drosophila

21 January 2018

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Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

21 January 2018

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

21 January 2018

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The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

21 January 2018

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Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer

21 January 2018

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Physical and functional interactions between Drosophila TRAF2 and Pelle kinase contribute to Dorsal activation.

21 January 2018

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Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

21 January 2018

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Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling

21 January 2018

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The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2.

21 January 2018

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Requirement for caspase-8 in NF-kappaB activation by antigen receptor.

21 January 2018

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The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M506655200

1 reference

5 May 2018

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5 May 2018