(Q37251086)

English

High glucose represses β-klotho expression and impairs fibroblast growth factor 21 action in mouse pancreatic islets: involvement of peroxisome proliferator-activated receptor γ signaling

scientific article published on 29 July 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

High glucose represses β-klotho expression and impairs fibroblast growth factor 21 action in mouse pancreatic islets: involvement of peroxisome proliferator-activated receptor γ signaling (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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object named as

Po Sing Leung

7

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Carmella Evans-Molina

4

object named as

Carmella Evans-Molina

1 reference

Europe PubMed Central

19 August 2017

PMC publication ID

author name string

Wing Yan So

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Qianni Cheng

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Lihua Chen

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Aimin Xu

5

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Europe PubMed Central

PMC publication ID

19 August 2017

Karen S L Lam

6

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Europe PubMed Central

PMC publication ID

19 August 2017

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publication date

29 July 2013

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Europe PubMed Central

PMC publication ID

19 August 2017

number of pages

9

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based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

62

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

3751-3759

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

30 August 2021

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April 2022 Public Data File from Crossref

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3806592/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

βKlotho is required for fibroblast growth factor 21 effects on growth and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

TNF-α represses β-Klotho expression and impairs FGF21 action in adipose cells: involvement of JNK1 in the FGF21 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

Relationship of serum fibroblast growth factor 21 with abnormal glucose metabolism and insulin resistance: the Baltimore Longitudinal Study of Aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

Growth hormone induces hepatic production of fibroblast growth factor 21 through a mechanism dependent on lipolysis in adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

Fibroblast growth factor 21 induces glucose transporter-1 expression through activation of the serum response factor/Ets-like protein-1 in adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

The role of peroxisome proliferator-activated receptor γ in pancreatic β cell function and survival: therapeutic implications for the treatment of type 2 diabetes mellitus

1 reference

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9 September 2017

Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

Role of glucotoxicity and lipotoxicity in the pathophysiology of Type 2 diabetes mellitus and emerging treatment strategies

1 reference

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9 September 2017

Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis

1 reference

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9 September 2017

The PPARgamma agonist pioglitazone ameliorates aging-related progressive renal injury

1 reference

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9 September 2017

Fibroblast growth factor-21 is induced in human skeletal muscles by hyperinsulinemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

FGF21 N- and C-termini play different roles in receptor interaction and activation

1 reference

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9 September 2017

In vivo and in vitro studies of a functional peroxisome proliferator-activated receptor gamma response element in the mouse pdx-1 promoter

1 reference

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9 September 2017

Fibroblast growth factor 21 corrects obesity in mice

1 reference

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9 September 2017

Research resource: nuclear hormone receptor expression in the endocrine pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

Fibroblast growth factor-21 as a therapeutic agent for metabolic diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21.

1 reference

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9 September 2017

Beta-cell preservation with thiazolidinediones

1 reference

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9 September 2017

FGF-21 as a novel metabolic regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

Identification and characterization of peroxisome proliferator response element in the mouse GLUT2 promoter

1 reference

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9 September 2017

Long-term glycaemic control with pioglitazone in patients with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

Role of peroxisome proliferator-activated receptor-gamma in the glucose-sensing apparatus of liver and beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

Serum response factor: discovery, biochemistry, biological roles and implications for tissue injury healing

1 reference

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9 September 2017

Phasic insulin release and metabolic regulation in type 2 diabetes.

1 reference

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9 September 2017

Diabetes mellitus and genetically programmed defects in beta-cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

The importance of the beta-cell in the pathogenesis of type 2 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

9 September 2017

FGF21 reloaded: challenges of a rapidly growing field

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

14 September 2017

Klotho is a target gene of PPAR-gamma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

14 September 2017

Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

14 September 2017

Circulating fibroblast growth factor-21 is elevated in impaired glucose tolerance and type 2 diabetes and correlates with muscle and hepatic insulin resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

26 June 2018

FGF-21/FGF-21 receptor interaction and activation is determined by betaKlotho

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

26 June 2018

Molecular determinants of FGF-21 activity-synergy and cross-talk with PPARgamma signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

26 June 2018

Angiotensin II exerts glucose-dependent effects on Kv currents in mouse pancreatic beta-cells via angiotensin II type 2 receptors

1 reference

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3 September 2018

Serum concentrations and tissue expression of a novel endocrine regulator fibroblast growth factor-21 in patients with type 2 diabetes and obesity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

3 September 2018

Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

3 September 2018

Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

3 September 2018

Angiotensin II type 1 receptor blockade improves beta-cell function and glucose tolerance in a mouse model of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

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Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

3 September 2018

Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel Klotho family protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

3 September 2018

The genetic basis of type 2 diabetes mellitus: impaired insulin secretion versus impaired insulin sensitivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806592

3 September 2018

The influence of age and dietary conditions on diabetes in the db mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/23897951

12 December 2020

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Expression of peroxisome proliferator-activated receptor γ (PPARγ) in normal human pancreatic islet cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23897951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DB13-0645

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

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