(Q37269248)

English

DEPTOR promotes survival of cervical squamous cell carcinoma cells and its silencing induces apoptosis through downregulating PI3K/AKT and by up-regulating p38 MAP kinase

scientific article published on 16 March 2016

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scholarly article

1 reference

Europe PubMed Central

19 August 2017

DEPTOR promotes survival of cervical squamous cell carcinoma cells and its silencing induces apoptosis through downregulating PI3K/AKT and by up-regulating p38 MAP kinase (English)

1 reference

Europe PubMed Central

19 August 2017

cervical squamous cell carcinoma

1 reference

based on heuristic

inferred from title

author name string

Kalanghad Puthankalam Srinivas

1

1 reference

Europe PubMed Central

19 August 2017

Remadevi Viji

2

1 reference

Europe PubMed Central

19 August 2017

Vipin Mohan Dan

3

1 reference

Europe PubMed Central

19 August 2017

Indira Sukumaran Sajitha

4

1 reference

Europe PubMed Central

19 August 2017

Rajappan Prakash

5

1 reference

Europe PubMed Central

19 August 2017

Puthan Valappil Rahul

6

1 reference

Europe PubMed Central

19 August 2017

Thankayyan R Santhoshkumar

7

1 reference

Europe PubMed Central

19 August 2017

Subhadra Lakshmi

8

1 reference

Europe PubMed Central

19 August 2017

Madhavan Radhakrishna Pillai

9

1 reference

Europe PubMed Central

19 August 2017

language of work or name

0 references

publication date

16 March 2016

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

7

1 reference

Europe PubMed Central

19 August 2017

17

1 reference

Europe PubMed Central

19 August 2017

24154-24171

1 reference

Europe PubMed Central

19 August 2017

Rap1 promotes endothelial mechanosensing complex formation, NO release and normal endothelial function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

DEPTOR has growth suppression activity against pancreatic cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

The overexpression of scaffolding protein NEDD9 promotes migration and invasion in cervical cancer via tyrosine phosphorylated FAK and SRC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Role of p38 and JNK MAPK signaling pathways and tumor suppressor p53 on induction of apoptosis in response to Ad-eIF5A1 in A549 lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Calpain and reactive oxygen species targets Bax for mitochondrial permeabilisation and caspase activation in zerumbone induced apoptosis

1 reference

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6 September 2017

Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR.

1 reference

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6 September 2017

Cellular entry of human papillomavirus type 16 involves activation of the phosphatidylinositol 3-kinase/Akt/mTOR pathway and inhibition of autophagy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

An evolving role for DEPTOR in tumor development and progression

1 reference

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6 September 2017

Targeting the mTOR-DEPTOR pathway by CRL E3 ubiquitin ligases: therapeutic application

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

AKT-dependent phosphorylation of Niban regulates nucleophosmin- and MDM2-mediated p53 stability and cell apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Regulation of TOR by small GTPases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Functional characterization of glycine N-methyltransferase and its interactive protein DEPDC6/DEPTOR in hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

DEPTOR, an mTOR inhibitor, is a physiological substrate of SCF(βTrCP) E3 ubiquitin ligase and regulates survival and autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

The human papillomavirus E6 oncogene represses a cell adhesion pathway and disrupts focal adhesion through degradation of TAp63β upon transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

E6 and E7 from human papillomavirus type 16 cooperate to target the PDZ protein Na/H exchange regulatory factor 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Overexpression of DEP domain containing mTOR-interacting protein correlates with poor prognosis in differentiated thyroid carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

mTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of action

1 reference

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6 September 2017

Nitric oxide induces early viral transcription coincident with increased DNA damage and mutation rates in human papillomavirus-infected cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Papillomavirus E6 proteins

1 reference

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6 September 2017

Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Apoptosis: controlled demolition at the cellular level

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Defining the role of mTOR in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Clonogenic assay of cells in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma

1 reference

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6 September 2017

Growing roles for the mTOR pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Mitogen-activated protein kinases in apoptosis regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Suppression of MEK/ERK signaling pathway enhances cisplatin-induced NF-kappaB activation by protein phosphatase 4-mediated NF-kappaB p65 Thr dephosphorylation

1 reference

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6 September 2017

Cell death: critical control points

1 reference

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6 September 2017

Differential effects of rapamycin on mammalian target of rapamycin signaling functions in mammalian cells

1 reference

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6 September 2017

The role of nitric oxide in cancer

1 reference

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Papillomaviruses and cancer: from basic studies to clinical application

1 reference

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6 September 2017

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

PUMA, a novel proapoptotic gene, is induced by p53

1 reference

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6 September 2017

Involvement of JNK-mediated pathway in EGF-mediated protection against paclitaxel-induced apoptosis in SiHa human cervical cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Identification of insulin receptor substrate 1 (IRS-1) and IRS-2 as signaling intermediates in the alpha6beta4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Mammalian MAP kinase signalling cascades

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029691

6 September 2017

Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways

1 reference

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6 September 2017

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

1 reference

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6 September 2017

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

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6 September 2017

Profiling of differentially expressed genes in human primary cervical cancer by complementary DNA expression array

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6 September 2017

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

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Differential expression of mTOR signalling components in drug resistance in ovarian cancer.

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The human papillomavirus type 16 E6 oncoprotein activates mTORC1 signaling and increases protein synthesis

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14 September 2017

Comparison of gene expression in squamous cell carcinoma and adenocarcinoma of the uterine cervix

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14 September 2017

Interferon-dependent activation of the serine kinase PI 3'-kinase requires engagement of the IRS pathway but not the Stat pathway

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26 June 2018

Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin.

1 reference

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The E7 protein from human papillomavirus type 16 enhances keratinocyte migration in an Akt-dependent manner

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3 September 2018

Cytochrome c is released in a single step during apoptosis

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3 September 2018

Human Papillomavirus Type 16 E7 Up-regulates AKT Activity through the Retinoblastoma Protein

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3 December 2018

Are adenocarcinomas and adenosquamous carcinomas different from squamous carcinomas in stage IB and II cervical cancer patients undergoing primary radical surgery?

1 reference

https://pubmed.ncbi.nlm.nih.gov/26992219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human papillomavirus and cervical cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/26992219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/ONCOTARGET.8131

1 reference

Europe PubMed Central

19 August 2017

release_ipnlptandbattbavjjz3m7m6ji

1 reference

https://api.fatcat.wiki/v0/release/ipnlptandbattbavjjz3m7m6ji

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

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