(Q37278215)

19 August 2017

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title

Role of the CXCR4/CXCL12 signaling axis in breast cancer metastasis to the brain (English)

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19 August 2017

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Cimona V Hinton

1

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Hava Karsenty Avraham

object named as

Hava Karsenty Avraham

series ordinal

3

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author name string

Shalom Avraham

series ordinal

2

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19 August 2017

language of work or name

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24 September 2008

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Clinical & Experimental Metastasis

19 August 2017

published in

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19 August 2017

volume

27

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19 August 2017

issue

2

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19 August 2017

page(s)

97-105

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Tumor metastasis to brain: role of endothelial cells, neurotrophins, and paracrine growth factors

19 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS10585-008-9210-2

Breast cancer metastasis to the central nervous system

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Early phase I data on an irreversible pan-erb inhibitor: CI-1033. What did we learn?

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Vascular endothelial growth factor in CSF: a biological marker for carcinomatous meningitis

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A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines

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12 December 2020

Expression of stromal cell-derived factor-1 and CXCR4 chemokine receptor mRNAs in cultured rat glial and neuronal cells

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12 December 2020

The risk of central nervous system metastases after trastuzumab therapy in patients with breast carcinoma

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Chemokine receptors in human endothelial cells. Functional expression of CXCR4 and its transcriptional regulation by inflammatory cytokines

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12 December 2020

Stromal cell-derived factor 1 regulates primitive hematopoiesis by suppressing apoptosis and by promoting G(0)/G(1) transition in CD34(+) cells: evidence for an autocrine/paracrine mechanism.

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12 December 2020

Identifying breast cancer patients at risk for Central Nervous System (CNS) metastases in trials of the International Breast Cancer Study Group (IBCSG).

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12 December 2020

The pro-inflammatory seven-transmembrane segment receptors of the leukocyte

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12 December 2020

Nerve growth factor is a potential therapeutic target in breast cancer

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12 December 2020

Chemoattractant signaling and leukocyte activation

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12 December 2020

Wound repair: the role of cytokines and vasoactive mediators

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12 December 2020

A gene expression signature associated with metastatic cells in effusions of breast carcinoma patients.

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12 December 2020

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

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12 December 2020

Nerve growth factor-induced migration of endothelial cells

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12 December 2020

The chemokines: cytokines that direct leukocyte migration

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12 December 2020

Molecular cloning and structure of a pre-B-cell growth-stimulating factor

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12 December 2020

Lung metastasis genes couple breast tumor size and metastatic spread.

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12 December 2020

Diagnosis and Management of Central Nervous System Metastases from Breast Cancer

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12 December 2020

Central nervous system metastases in women who receive trastuzumab-based therapy for metastatic breast carcinoma

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12 December 2020

Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice

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12 December 2020

Chemokine networks and breast cancer metastasis.

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12 December 2020

Brain metastases in breast cancer; natural history, prognostic factors and outcome

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12 December 2020

Functional expression of the CXC-chemokine receptor-4/fusin on mouse microglial cells and astrocytes.

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12 December 2020

Stromal effects on mammary gland development and breast cancer

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12 December 2020

Breakdown of the Blood–Brain Barrier After Fluid Percussion Brain Injury in the Rat: Part 2: Effect of Hypoxia on Permeability to Plasma Proteins

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12 December 2020

Molecular cloning of cDNAs encoding a LD78 receptor and putative leukocyte chemotactic peptide receptors

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12 December 2020

Nerve growth factor mediates its pro-invasive effect in parallel with the release of a soluble E-cadherin fragment from breast cancer MCF-7/AZ cells.

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12 December 2020

Nerve growth factor receptors and signaling in breast cancer

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12 December 2020

CXCL12/CXCR4 transactivates HER2 in lipid rafts of prostate cancer cells and promotes growth of metastatic deposits in bone

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12 December 2020

Chemokine receptor CXCR4 expression in endothelium

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12 December 2020

Isolation and characterization of a novel secretory protein, stromal cell-derived factor-2 (SDF-2) using the signal sequence trap method

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12 December 2020

A possible role for CXCR4 and its ligand, the CXC chemokine stromal cell-derived factor-1, in the development of bone marrow metastases in neuroblastoma

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12 December 2020

Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells

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12 December 2020

NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4

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12 December 2020

Occult central nervous system involvement in patients with metastatic breast cancer: prevalence, predictive factors and impact on overall survival

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12 December 2020

Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro

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12 December 2020

CXCR4 is a major chemokine receptor on glioma cells and mediates their survival

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12 December 2020

Chemokine-receptor interactions: GPCRs, glycosaminoglycans and viral chemokine binding proteins

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12 December 2020

Cell-matrix interactions during development and apoptosis of the mouse mammary gland in vivo.

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12 December 2020

A multigenic program mediating breast cancer metastasis to bone

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12 December 2020

Rapid increase in blood-brain barrier permeability during severe hypoxia and metabolic inhibition.

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12 December 2020

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

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12 December 2020

Vascular endothelial growth factor modulates the transendothelial migration of MDA-MB-231 breast cancer cells through regulation of brain microvascular endothelial cell permeability

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12 December 2020

Breast cancer brain metastases

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12 December 2020

The biology of vascular endothelial growth factor

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12 December 2020

Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain

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12 December 2020

Lapatinib: a dual inhibitor of EGFR and HER2 tyrosine kinase activity

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12 December 2020

Not so strange bedfellows: G-protein-coupled receptors and Src family kinases

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12 December 2020

CXCL-12/stromal cell-derived factor-1alpha transactivates HER2-neu in breast cancer cells by a novel pathway involving Src kinase activation

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12 December 2020

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12 December 2020

Chemokines--chemotactic cytokines that mediate inflammation

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12 December 2020

Vascular endothelial growth factor expression promotes the growth of breast cancer brain metastases in nude mice

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12 December 2020

Chemokines and their receptors in lymphocyte traffic and HIV infection

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12 December 2020

T140 analogs as CXCR4 antagonists identified as anti-metastatic agents in the treatment of breast cancer

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12 December 2020

A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors.

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12 December 2020

Involvement of chemokine receptors in breast cancer metastasis

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12 December 2020

Transactivation of ErbB1 and ErbB2 receptors by angiotensin II in normal human prostate stromal cells

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12 December 2020

Expression pattern of CXC chemokine receptor-4 is correlated with lymph node metastasis in human invasive ductal carcinoma

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12 December 2020

Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms.

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12 December 2020

EGFR signal transactivation in cancer cells

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12 December 2020

CXCR4 activation induces epidermal growth factor receptor transactivation in an ovarian cancer cell line.

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12 December 2020

Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines

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12 December 2020

CD4-independent association between HIV-1 gp120 and CXCR4: functional chemokine receptors are expressed in human neurons

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12 December 2020

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

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12 December 2020

HER2 in brain metastases: issues of concordance, survival, and treatment.

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12 December 2020

Brain metastases from breast cancer: clinical course, prognosis and influence of treatment

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12 December 2020

Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation

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12 December 2020

Mediators of vascular remodelling co-opted for sequential steps in lung metastasis.

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12 December 2020

Central nervous system metastasis in breast cancer

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12 December 2020

In vivo selection for metastasis promoting genes in the mouse

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12 December 2020

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

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12 December 2020

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

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12 December 2020

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

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12 December 2020

Efficacy of intracerebral microinfusion of trastuzumab in an athymic rat model of intracerebral metastatic breast cancer.

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12 December 2020

Molecular cloning of the cDNA and chromosomal localization of the gene for a putative seven-transmembrane segment (7-TMS) receptor isolated from human spleen

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12 December 2020

Chemokines, inflammation and the immune system

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12 December 2020

Three-dimensional structures of alpha and beta chemokines.

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12 December 2020

Endothelial cells differentially express functional CXC-chemokine receptor-4 (CXCR-4/fusin) under the control of autocrine activity and exogenous cytokines

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12 December 2020

Oestrogen receptors, sites of metastatic disease and survival in recurrent breast cancer

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12 December 2020

Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene

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12 December 2020

CNS metastases in breast cancer

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12 December 2020

Human chemokines: an update

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12 December 2020

Chemokines and leukocyte traffic

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12 December 2020

Incidence of cerebral metastases in patients treated with trastuzumab for metastatic breast cancer.

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12 December 2020

Cancer and the chemokine network

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12 December 2020

Nerve growth factor overexpression and autocrine loop in breast cancer cells

1 reference

12 December 2020

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1 reference

12 December 2020

Chemokine receptors: gateways to inflammation and infection

1 reference

12 December 2020

Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis.

1 reference

12 December 2020

Vascular endothelial growth factor (VEGF) and its receptors

1 reference

12 December 2020

Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer

1 reference

12 December 2020

Chemokines: a new classification system and their role in immunity

1 reference

12 December 2020

Tumor necrosis factor receptor-associated death domain protein is involved in the neurotrophin receptor-mediated antiapoptotic activity of nerve growth factor in breast cancer cells

1 reference

12 December 2020

Molecular characterization of the tumor microenvironment in breast cancer

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12 December 2020

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

1 reference

12 December 2020

The p160 family coactivators regulate breast cancer cell proliferation and invasion through autocrine/paracrine activity of SDF-1alpha/CXCL12.

1 reference

12 December 2020

10.1007/S10585-008-9210-2

Identifiers

DOI

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19 August 2017

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