(Q45111099)

9 December 2017

Not so strange bedfellows: G-protein-coupled receptors and Src family kinases (English)

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G protein-coupled receptor

9 December 2017

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author name string

Deirdre K Luttrell

series ordinal

1

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9 December 2017

Louis M Luttrell

series ordinal

2

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9 December 2017

language of work or name

English

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publication date

1 October 2004

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9 December 2017

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9 December 2017

23

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9 December 2017

7969-7978

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9 December 2017

48

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208162

9 December 2017

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cites work

Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Overexpression of c-src enhances beta-adrenergic-induced cAMP accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Direct binding of activated c-Src to the beta 3-adrenergic receptor is required for MAP kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Role of tyrosine kinase activity of epidermal growth factor receptor in the lysophosphatidic acid-stimulated mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta -arrestin-dependent scaffolding complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Identification of a new Pyk2 isoform implicated in chemokine and antigen receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

c-Src tyrosine kinase binds the beta 2-adrenergic receptor via phospho-Tyr-350, phosphorylates G-protein-linked receptor kinase 2, and mediates agonist-induced receptor desensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

EGF receptor phosphorylation is affected by ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Tyrosine phosphorylation of G protein alpha subunits by pp60c-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

A calcium-dependent tyrosine kinase splice variant in human monocytes. Activation by a two-stage process involving adherence and a subsequent intracellular signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Src homology 3 binding sites in the P2Y2 nucleotide receptor interact with Src and regulate activities of Src, proline-rich tyrosine kinase 2, and growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Transformation of Rat-1 fibroblasts with the v-src oncogene increases the tyrosine phosphorylation state and activity of the alpha subunit of Gq/G11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Expanding roles for beta-arrestins as scaffolds and adapters in GPCR signaling and trafficking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

G protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase.Shc adapter protein signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Matrix metalloproteinases 2 and 9 mediate epidermal growth factor receptor transactivation by gonadotropin-releasing hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Agonist-dependent phosphorylation of the G protein-coupled receptor kinase 2 (GRK2) by Src tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

c-Cbl is transiently tyrosine-phosphorylated, ubiquitinated, and membrane-targeted following CSF-1 stimulation of macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Rapid transactivation of the vascular endothelial growth factor receptor KDR/Flk-1 by the bradykinin B2 receptor contributes to endothelial nitric-oxide synthase activation in cardiac capillary endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Essential role of dynamin in internalization of M2 muscarinic acetylcholine and angiotensin AT1A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Differential regulation of Pyk2 and focal adhesion kinase (FAK). The C-terminal domain of FAK confers response to cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Electroporation of pp60c−srcAntibodies Inhibits the Angiotensin II Activation of Phospholipase C-γ1 in Rat Aortic Smooth Muscle Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Angiotensin II Controls p21 Activity via pp60

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Thrombin Stimulates Phosphorylation of Insulin-like Growth Factor-1 Receptor, Insulin Receptor Substrate-1, and Phospholipase C-γ1 in Rat Aortic Smooth Muscle Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Dynamin associates with Src-Homology Collagen (Shc) and becomes tyrosine phosphorylated in response to insulin

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Structure and regulation of Src family kinases

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Regulation of a calcium-dependent tyrosine kinase in vascular smooth muscle cells by angiotensin II and platelet-derived growth factor. Dependence on calcium and the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

The interplay between Src family kinases and receptor tyrosine kinases

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

The when and how of Src regulation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Trafficking and proteolytic release of epidermal growth factor receptor ligands are modulated by their membrane-anchoring domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Angiotensin II Induces Transactivation of Two Different Populations of the Platelet-derived Growth Factor β Receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Requirement of receptor internalization for opioid stimulation of mitogen-activated protein kinase: biochemical and immunofluorescence confocal microscopic evidence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Thrombin induces activation of p38 MAP kinase in human platelets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

The role of receptor kinases and arrestins in G protein-coupled receptor regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascades in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Src tyrosine kinase is a novel direct effector of G proteins.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors: a co-culture system for identifying intermediates upstream and downstream of heparin-binding EGF shedding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

G protein-coupled receptor kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

The interplay between Src and integrins in normal and tumor biology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Emerging roles for p120-catenin in cell adhesion and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Transactivation of the EGF receptor mediates IGF-1-stimulated shc phosphorylation and ERK1/2 activation in COS-7 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Nuclear signaling by endothelin-1 requires Src protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Critical role of calcium- dependent epidermal growth factor receptor transactivation in PC12 cell membrane depolarization and bradykinin signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208162

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208162

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Dimensions Publication ID

9 December 2017

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