(Q77726430)

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Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases

scientific article published on 01 May 1999

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10318809%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10318809%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

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G J Della Rocca

1

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7 December 2019

S Maudsley

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10318809%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

Y Daaka

3

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7 December 2019

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1 May 1999

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7 December 2019

Journal of Biological Chemistry

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7 December 2019

274

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7 December 2019

20

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7 December 2019

13978-13984

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7 December 2019

Bombesin, bradykinin, vasopressin, and phorbol esters rapidly and transiently activate Src family tyrosine kinases in Swiss 3T3 cells. Dissociation from tyrosine phosphorylation of p125 focal adhesion kinase

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Angiotensin II Activates pp60 c- src in Vascular Smooth Muscle Cells

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Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

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The m1 muscarinic acetylcholine receptor transactivates the EGF receptor to modulate ion channel activity

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Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases

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Bradykinin receptors: pharmacological properties and biological roles

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Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins.

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G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1a fibroblasts. Shc phosphorylation and receptor endocytosis correlate with activation of Erk kinases

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Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascades in vascular smooth muscle cells

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Integrins and signal transduction pathways: the road taken

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Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

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A calcium-dependent tyrosine kinase splice variant in human monocytes. Activation by a two-stage process involving adherence and a subsequent intracellular signal

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Signal characteristics of G protein-transactivated EGF receptor

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Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway

1 reference

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Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

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Integrins: versatility, modulation, and signaling in cell adhesion

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Thrombin Stimulates Phosphorylation of Insulin-like Growth Factor-1 Receptor, Insulin Receptor Substrate-1, and Phospholipase C-γ1 in Rat Aortic Smooth Muscle Cells

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Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells

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Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

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G protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase.Shc adapter protein signaling complexes

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Ligand binding regulates the directed movement of beta1 integrins on fibroblasts

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Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells

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Differential coupling of alpha1-, alpha2-, and beta-adrenergic receptors to mitogen-activated protein kinase pathways and differentiation in transfected PC12 cells

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Tyrosine phosphorylation of paxillin and focal adhesion kinase by activation of muscarinic m3 receptors is dependent on integrin engagement by the extracellular matrix

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Identification of a new Pyk2 isoform implicated in chemokine and antigen receptor signaling

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Differential regulation of Pyk2 and focal adhesion kinase (FAK). The C-terminal domain of FAK confers response to cell adhesion

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Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src

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Integrin signalling and tyrosine phosphorylation: just the FAKs?

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Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation

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A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

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Differential activation of p44mapk (ERK1) by alpha-thrombin and thrombin-receptor peptide agonist

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Distinct pathways of Gi- and Gq-mediated mitogen-activated protein kinase activation

1 reference

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Identifiers

10.1074/JBC.274.20.13978

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10318809%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10318809%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

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