(Q37278398)

English

IL-4Ralpha responsiveness of non-CD4 T cells contributes to resistance in schistosoma mansoni infection in pan-T cell-specific IL-4Ralpha-deficient mice.

scientific article published on 23 July 2009

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19628763%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

IL-4Ralpha responsiveness of non-CD4 T cells contributes to resistance in schistosoma mansoni infection in pan-T cell-specific IL-4Ralpha-deficient mice (English)

1 reference

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3 February 2020

Schistosoma mansoni

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Benjamin G Dewals

1

1 reference

Europe PubMed Central

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3 February 2020

Antony J Cutler

6

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3 February 2020

author name string

Jennifer C Hoving

2

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3 February 2020

Mosiuoa Leeto

3

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3 February 2020

Reece G Marillier

4

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3 February 2020

Umeshree Govender

5

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3 February 2020

William G C Horsnell

7

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3 February 2020

Frank Brombacher

8

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3 February 2020

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23 July 2009

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3 February 2020

The American Journal of Pathology

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3 February 2020

175

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3 February 2020

2

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3 February 2020

706-716

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3 February 2020

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2716945/fullTextXML

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inferred from PubMed Central ID database lookup

IL-10 and TGF-beta redundantly protect against severe liver injury and mortality during acute schistosomiasis

1 reference

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Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system

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Protective immune mechanisms in helminth infection

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Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance

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6 September 2017

Deletion of IL-4Ralpha on CD4 T cells renders BALB/c mice resistant to Leishmania major infection.

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TH1-dominant granulomatous pathology does not inhibit fibrosis or cause lethality during murine schistosomiasis

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Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells

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Interleukin-4 receptor alpha-deficient BALB/c mice show an unimpaired T helper 2 polarization in response to Leishmania major infection

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The IL-4 receptor: signaling mechanisms and biologic functions

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Unimpaired down-modulation of the hepatic granulomatous response in CD8 T-cell- and gamma interferon-deficient mice chronically infected with Schistosoma mansoni

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Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

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Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

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Acquisition of lymphokine-producing phenotype by CD4+ T cells

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Delayed hypersensitivity-type granuloma formation and dermal reaction induced and elicited by a soluble factor isolated from Schistosoma mansoni eggs

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Helper T-cell subsets in mouse leishmaniasis: induction, expansion and effector function

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The regulation of immunity to Leishmania major

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Impairment of alternative macrophage activation delays cutaneous leishmaniasis in nonhealing BALB/c mice.

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Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology.

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Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agent

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IL-4-deficient Balb/c mice resist infection with Leishmania major

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Conditional gene targeting

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Th2 cells are required for the Schistosoma mansoni egg-induced granulomatous response.

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Schistosome-infected IL-4 receptor knockout (KO) mice, in contrast to IL-4 KO mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profile

1 reference

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IL-10 and the dangers of immune polarization: excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis

1 reference

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Characterization of granuloma T lymphocyte function from Schistosoma mansoni-infected mice

1 reference

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Determination of arginase activity in macrophages: a micromethod

1 reference

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Susceptibility to Leishmania major infection in interleukin-4-deficient mice

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2353/AJPATH.2009.090137

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19628763%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

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3 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19628763%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

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