(Q37280672)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

title

Disruption of Bax protein prevents neuronal cell death but produces cognitive impairment in mice following traumatic brain injury (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

main subject

traumatic brain injury

0 references

cognitive dysfunction

1 reference

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Patrick M. Kochanek

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

author name string

Roya Tehranian

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Marie E Rose

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Vincent Vagni

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Raymond P Griffith

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Hao Liu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Robert S B Clark

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

C Edward Dixon

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Steven H Graham

10

1 reference

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10 January 2020

publication date

1 July 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

published in

Journal of Neurotrauma

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

volume

25

1 reference

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10 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

page(s)

755-767

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

10 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia.

6 September 2017

1 reference

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Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Traumatic brain injury in infants and children: mechanisms of secondary damage and treatment in the intensive care unit

6 September 2017

1 reference

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Temporal alterations in cellular Bax:Bcl-2 ratio following traumatic brain injury in the rat

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Targeting programmed cell death in neurodegenerative diseases

6 September 2017

1 reference

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Caspase-3 apoptotic signaling following injury to the central nervous system.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Bcl-2 family gene products in cerebral ischemia and traumatic brain injury

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Programmed cell death of embryonic motoneurons triggered through the Fas death receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Temporal profile of neuronal damage in a model of transient forebrain ischemia

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Inhibition of Bax-induced cytochrome c release from neural cell and brain mitochondria by dibucaine and propranolol.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Bax-independent inhibition of apoptosis by Bcl-XL.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

The Dorothy Russell Memorial Lecture. The molecular and cellular sequelae of experimental traumatic brain injury: pathogenetic mechanisms

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Apoptosis-suppressor gene bcl-2 expression after traumatic brain injury in rats.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Early neuropathologic effects of mild or moderate hypoxemia after controlled cortical impact injury in rats

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Apoptosis repressor genes Bcl-2 and Bcl-x-long are expressed in the rat brain following global ischemia

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Altered expression of Bcl-2, Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Transgenic mice that overexpress the anti-apoptotic Bcl-2 protein have improved histological outcome but unchanged behavioral outcome after traumatic brain injury

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Isoflurane exerts neuroprotective actions at or near the time of severe traumatic brain injury

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Evaluation of the apoptosis-related proteins of the BCL-2 family in the traumatic penumbra area of the rat model of cerebral contusion, treated by hyperbaric oxygen therapy: a quantitative immunohistochemical study

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Bax ablation protects against myocardial ischemia-reperfusion injury in transgenic mice

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Characterization of Bax and Bcl-2 in apoptosis after experimental traumatic brain injury in the rat.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Isoflurane improves long-term neurologic outcome versus fentanyl after traumatic brain injury in rats.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Overexpression of Bcl-2 is neuroprotective after experimental brain injury in transgenic mice

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Reduction of cognitive and motor deficits after traumatic brain injury in mice deficient in poly(ADP-ribose) polymerase

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Bcl-2 family proteins and mitochondria.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Immunohistochemical analysis of in vivo patterns of Bak expression, a proapoptotic member of the Bcl-2 protein family.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Increases in bcl-2 protein in cerebrospinal fluid and evidence for programmed cell death in infants and children after severe traumatic brain injury

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2717742

Expression of the apoptosis-effector gene, Bax, is up-regulated in vulnerable hippocampal CA1 neurons following global ischemia

3 December 2018

1 reference

12 December 2020

Bak BH3 peptides antagonize Bcl-xL function and induce apoptosis through cytochrome c-independent activation of caspases

1 reference

12 December 2020

Caspase-3 mediated neuronal death after traumatic brain injury in rats

1 reference

12 December 2020

Fas (CD95/APO-1) plays a role in the pathophysiology of focal cerebral ischemia

1 reference

12 December 2020

Detection of single- and double-strand DNA breaks after traumatic brain injury in rats: comparison of in situ labeling techniques using DNA polymerase I, the Klenow fragment of DNA polymerase I, and terminal deoxynucleotidyl transferase

1 reference

12 December 2020

Involvement of mitochondria in ischemic cell injury and in regulation of intracellular calcium

1 reference

12 December 2020

The role of excitatory amino acids and NMDA receptors in traumatic brain injury

1 reference

12 December 2020

Identifiers

DOI

10.1089/NEU.2007.0441

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18627254%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

PubMed publication ID

18627254

1 reference