(Q37283568)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828015%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

review article

1 reference

title

Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828015%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828015%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Herve Boutin

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828015%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Nadja Van Camp

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828015%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Bertrand Tavitian

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828015%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

author name string

Frédéric Dollé

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828015%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

publication date

1 October 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828015%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Nuclear Medicine and Molecular Imaging

15 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828015%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

volume

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828015%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828015%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

page(s)

2304-2319

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828015%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00259-008-0908-9

15 January 2020

exact match

0 references

cites work

Innate and adaptive immune responses of the central nervous system

1 reference

https://api.crossref.org/works/10.1007%2FS00259-008-0908-9

Dynamics of polymorphonuclear leukocyte accumulation in acute cerebral infarction and their correlation with brain tissue damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00259-008-0908-9

Heterogeneity of blood-brain barrier changes in multiple sclerosis: an MRI study with gadolinium-DTPA enhancement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00259-008-0908-9

Assessment of neuroinflammation and microglial activation in Alzheimer's disease with radiolabelled PK11195 and single photon emission computed tomography. A pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00259-008-0908-9

VCAM-1-positive microglia target oligodendrocytes at the border of multiple sclerosis lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00259-008-0908-9

Radiolabeled leucocyte imaging in diffuse granulomatous involvement of the meninges in Wegener's granulomatosis: scintigraphic findings and their role in monitoring treatment response to specific immunotherapy (humanized monoclonal antilymphocyte an

21 January 2018

1 reference

12 December 2020

Synthesis, fluorine-18 radiolabeling, and in vitro characterization of 1-iodophenyl-N-methyl-N-fluoroalkyl-3-isoquinoline carboxamide derivatives as potential PET radioligands for imaging peripheral benzodiazepine receptor

1 reference

12 December 2020

MRI detection of early endothelial activation in brain inflammation

1 reference

12 December 2020

Longitudinal, quantitative assessment of amyloid, neuroinflammation, and anti-amyloid treatment in a living mouse model of Alzheimer's disease enabled by positron emission tomography

1 reference

12 December 2020

Microglial cell population dynamics in the injured adult central nervous system

1 reference

12 December 2020

Differential blood-brain barrier breakdown and leucocyte recruitment following excitotoxic lesions in juvenile and adult rats.

1 reference

12 December 2020

MR molecular imaging of early endothelial activation in focal ischemia

1 reference

12 December 2020

Synthesis and evaluation of two positron-labeled nitric oxide synthase inhibitors, S-[11C]methylisothiourea and S-(2-[18F]fluoroethyl)isothiourea, as potential positron emission tomography tracers

1 reference

12 December 2020

Visualising microglial activation in vivo

1 reference

12 December 2020

Increased binding of peripheral benzodiazepine receptor in Alzheimer's disease measured by positron emission tomography with [11C]DAA1106.

1 reference

12 December 2020

Inflammatory response after ischemic stroke: a USPIO-enhanced MRI study in patients.

1 reference

12 December 2020

Evaluation of reference regions for (R)-[(11)C]PK11195 studies in Alzheimer's disease and mild cognitive impairment.

1 reference

12 December 2020

2-Phenyl-imidazo[1,2-a]pyridine derivatives as ligands for peripheral benzodiazepine receptors: stimulation of neurosteroid synthesis and anticonflict action in rats.

1 reference

12 December 2020

Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis

1 reference

12 December 2020

Cobalt-55 positron emission tomography in vascular dementia: significance of white matter changes.

1 reference

12 December 2020

Peripheral type benzodiazepine binding sites are a sensitive indirect index of neuronal damage.

1 reference

12 December 2020

Quantitative analysis for estimating binding potential of the peripheral benzodiazepine receptor with [(11)C]DAA1106.

1 reference

12 December 2020

Chemokine receptor 5 antagonist D-Ala-peptide T-amide reduces microglia and astrocyte activation within the hippocampus in a neuroinflammatory rat model of Alzheimer's disease

1 reference

12 December 2020

The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imaging

1 reference

12 December 2020

Tc-99m exametazime-labeled leukocyte scans in the study of infections in skull neurosurgery

1 reference

12 December 2020

Down-regulation of the macrophage lineage through interaction with OX2 (CD200)

1 reference

12 December 2020

Synthesis of the enantiomers of [N-methyl-11C]PK 11195 and comparison of their behaviours as radioligands for PK binding sites in rats.

1 reference

12 December 2020

[(11)C]DAA1106: radiosynthesis and in vivo binding to peripheral benzodiazepine receptors in mouse brain

1 reference

12 December 2020

Cobalt-57 and technetium-99m-HMPAO-labeled leukocytes for visualization of ischemic infarcts.

1 reference

12 December 2020

PET studies on the brain uptake and regional distribution of [11C]vinpocetine in human subjects

1 reference

12 December 2020

The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds specifically to microglia in a rat model of traumatic brain injury: implications for PET imaging

1 reference

12 December 2020

Synthesis and evaluation of a fluorine-18 labeled antisense oligonucleotide as a potential PET tracer for iNOS mRNA expression

1 reference

12 December 2020

Site-directed mutagenesis of the peripheral benzodiazepine receptor: identification of amino acids implicated in the binding site of Ro5-4864

1 reference

12 December 2020

The discovery of a novel macrophage binding site

1 reference

12 December 2020

Imaging inflammation in acute brain ischemia

1 reference

12 December 2020

Synthesis, labeling, and biological evaluation of halogenated 2-quinolinecarboxamides as potential radioligands for the visualization of peripheral benzodiazepine receptors

1 reference

12 December 2020

N,N-dialkyl-2-phenylindol-3-ylglyoxylamides. A new class of potent and selective ligands at the peripheral benzodiazepine receptor.

1 reference

12 December 2020

Antianxiety and antidepressant-like effects of AC-5216, a novel mitochondrial benzodiazepine receptor ligand

1 reference

12 December 2020

Ultrasound derived imaging and quantification of cell adhesion molecules in experimental autoimmune encephalomyelitis (EAE) by Sensitive Particle Acoustic Quantification (SPAQ).

1 reference

12 December 2020

Early and reversible neuropathology induced by tetracycline-regulated lentiviral overexpression of mutant huntingtin in rat striatum

1 reference

12 December 2020

Inflammation in stroke: the good, the bad, and the unknown

1 reference

12 December 2020

Imaging brain inflammation with [(11)C]PK11195 by PET and induction of the peripheral-type benzodiazepine receptor after transient focal ischemia in rats.

1 reference

12 December 2020

Strategy for improved [(11)C]DAA1106 radiosynthesis and in vivo peripheral benzodiazepine receptor imaging using microPET, evaluation of [(11)C]DAA1106.

1 reference

12 December 2020

A general method for the synthesis of aryl [11C]methylsulfones: potential PET probes for imaging cyclooxygenase-2 expression

1 reference

12 December 2020

Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function

1 reference

12 December 2020

In vivo imaging of neuroinflammation

1 reference

12 December 2020

A comparison of the high-affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)-PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation

1 reference

12 December 2020

Brain uptake and plasma metabolism of [11C]vinpocetine: a preliminary PET study in a cynomolgus monkey

1 reference

12 December 2020

Cerebral uptake of [ethyl-11C]vinpocetine and 1-[11C]ethanol in cynomolgous monkeys: a comparative preclinical PET study

1 reference

12 December 2020

Evaluation of a radiolabelled peripheral benzodiazepine receptor ligand in the central nervous system inflammation of experimental autoimmune encephalomyelitis: a possible probe for imaging multiple sclerosis

1 reference

12 December 2020

Matrix metalloproteinases in neuroinflammation

1 reference

12 December 2020

SPM analysis of parametric (R)-[11C]PK11195 binding images: plasma input versus reference tissue parametric methods.

1 reference

12 December 2020

Development of ligands for the peripheral benzodiazepine receptor

1 reference

12 December 2020

2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR)

1 reference

12 December 2020

In-vivo measurement of activated microglia in dementia

1 reference

12 December 2020

Radiosynthesis, in vitro validation, and in vivo evaluation of 18F-labeled COX-1 and COX-2 inhibitors.

1 reference

12 December 2020

The concept of in vivo imaging of neuroinflammation with [11C](R)-PK11195 PET.

1 reference

12 December 2020

Imaging glial cell activation with [11C]-R-PK11195 in patients with AIDS.

1 reference

12 December 2020

Synthesis and in vivo evaluation of a novel peripheral benzodiazepine receptor PET radioligand

1 reference

12 December 2020

N-(5-Fluoro-2-phenoxyphenyl)-N-(2-[(131)I]iodo-5-me thoxybenzyl)acetamide: a potent iodinated radioligand for the peripheral-type benzodiazepine receptor in brain.

1 reference

12 December 2020

Labeling and evaluation of N-[11C]methylated quinoline-2-carboxamides as potential radioligands for visualization of peripheral benzodiazepine receptors

1 reference

12 December 2020

Improved synthesis of the peripheral benzodiazepine receptor ligand [11C]DPA-713 using [11C]methyl triflate.

1 reference

12 December 2020

In vitro and ex vivo autoradiography studies on peripheral-type benzodiazepine receptor binding using [11C]AC-5216 in normal and kainic acid-lesioned rats

1 reference

12 December 2020

Connexin43, the major gap junction protein of astrocytes, is down-regulated in inflamed white matter in an animal model of multiple sclerosis

1 reference

12 December 2020

Technetium-99m hexamethylpropylene amine oxime leucocyte scintigraphy in the differential diagnosis of cerebral abscesses

1 reference

12 December 2020

Synthesis and receptor binding studies of halogenated N,N-dialkylel-(2-phenyl-1H-indol-3-yl)glyoxylamides to visualize peripheral benzodiazepine receptors with SPECT or PET.

1 reference

12 December 2020

Quantitative analyses of 18F-FEDAA1106 binding to peripheral benzodiazepine receptors in living human brain.

1 reference

12 December 2020

Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain

1 reference

12 December 2020

Synthesis and in vivo evaluation of 18F-desbromo-DuP-697 as a PET tracer for cyclooxygenase-2 expression

1 reference

12 December 2020

A systematic comparison of kinetic modelling methods generating parametric maps for [(11)C]-(R)-PK11195.

1 reference

12 December 2020

[18F]FMDAA1106 and [18F]FEDAA1106: two positron-emitter labeled ligands for peripheral benzodiazepine receptor (PBR).

1 reference

12 December 2020

Characterization of binding sites for the omega3 receptor ligands [3H]PK11195 and [3H]RO5-4864 in human brain.

1 reference

12 December 2020

Positron emission tomography imaging of peripheral benzodiazepine receptor binding in human immunodeficiency virus-infected subjects with and without cognitive impairment.

1 reference

12 December 2020

Pharmacological evaluation of an [(123)I] labelled imidazopyridine-3-acetamide for the study of benzodiazepine receptors

1 reference

12 December 2020

The use of imaging in the early development of neuropharmacological drugs: a survey of approved NDAs

1 reference

12 December 2020

PET imaging with [11C]PBR28 can localize and quantify upregulated peripheral benzodiazepine receptors associated with cerebral ischemia in rat.

1 reference

12 December 2020

Development of a tracer kinetic plasma input model for (R)-[11C]PK11195 brain studies

1 reference

12 December 2020

Reference and target region modeling of [11C]-(R)-PK11195 brain studies

1 reference

12 December 2020

Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study.

1 reference

12 December 2020

The significance of cobalt-55 positron emission tomography in ischemic stroke.

1 reference

12 December 2020

Evaluation of methods for generating parametric (R-[11C]PK11195 binding images.

1 reference

12 December 2020

A new focal EAE model of cortical demyelination: multiple sclerosis-like lesions with rapid resolution of inflammation and extensive remyelination.

1 reference

12 December 2020

Synthesis and evaluation of N-(5-fluoro-2-phenoxyphenyl)-N-(2-[(18)F]fluoromethoxy-d(2)-5-methoxybenzyl)acetamide: a deuterium-substituted radioligand for peripheral benzodiazepine receptor

1 reference

12 December 2020

Radiosynthesis and initial evaluation of [18F]-FEPPA for PET imaging of peripheral benzodiazepine receptors

1 reference

12 December 2020

Anti-VCAM-1 antibodies did not protect against ischemic damage either in rats or in mice

1 reference

12 December 2020

Intrinsic activated microglia map to the peri-infarct zone in the subacute phase of ischemic stroke.

1 reference

12 December 2020

Synthesis and evaluation in monkey of two sensitive 11C-labeled aryloxyanilide ligands for imaging brain peripheral benzodiazepine receptors in vivo

1 reference

12 December 2020

11C-DPA-713: a novel peripheral benzodiazepine receptor PET ligand for in vivo imaging of neuroinflammation.

1 reference

12 December 2020

Radiolabeled neuronal nitric oxide synthase inhibitors: synthesis, in vivo evaluation, and primate PET studies

1 reference

12 December 2020

PET imaging of human gliomas with ligands for the peripheral benzodiazepine binding site.

1 reference

12 December 2020

In vivo binding to peripheral benzodiazepine binding sites in lesioned rat brain: comparison between [3H]PK11195 and [18F]PK14105 as markers for neuronal damage.

1 reference

12 December 2020

[11C]vinpocetine: a prospective peripheral benzodiazepine receptor ligand for primate PET studies

1 reference

12 December 2020

Synthesis and evaluation of [123I]-iodo-PK11195 for mapping peripheral-type benzodiazepine receptors (omega 3) in heart

1 reference

12 December 2020

Induction of type 2 iodothyronine deiodinase in astrocytes after transient focal cerebral ischemia in the rat.

1 reference

12 December 2020

Peripheral benzodiazepine receptors: on mice and human brain imaging

1 reference

12 December 2020

Peripheral benzodiazepine binding sites in human gliomas evaluated with positron emission tomography.

1 reference

12 December 2020

Synthesis, in vivo evaluation and PET study of a carbon-11-labeled neuronal nitric oxide synthase (nNOS) inhibitor S-methyl-L-thiocitrulline.

1 reference

12 December 2020

55Cobalt (Co) as a PET-tracer in stroke, compared with blood flow, oxygen metabolism, blood volume and gadolinium-MRI.

1 reference

12 December 2020

Toll-like receptor 2 signaling in response to brain injury: an innate bridge to neuroinflammation.

1 reference

12 December 2020

Radioiodinated benzodiazepines: agents for mapping glial tumors

1 reference

12 December 2020

Inflammation in Alzheimer disease: driving force, bystander or beneficial response?

1 reference

12 December 2020

Functional neuroimaging in multiple sclerosis with radiolabelled glia markers: preliminary comparative PET studies with [11C]vinpocetine and [11C]PK11195 in patients.

1 reference

12 December 2020

Synthesis of 18F-labelled cyclooxygenase-2 (COX-2) inhibitors via Stille reaction with 4-[18F]fluoroiodobenzene as radiotracers for positron emission tomography (PET).

1 reference

12 December 2020

11C-AC-5216: a novel PET ligand for peripheral benzodiazepine receptors in the primate brain

1 reference

12 December 2020

Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation

1 reference

12 December 2020

[2-11C]isopropyl-, [1-11C]ethyl-, and [11C]methyl-labeled phenoxyphenyl acetamide derivatives as positron emission tomography ligands for the peripheral benzodiazepine receptor: radiosynthesis, uptake, and in vivo binding in brain.

1 reference

12 December 2020

Is damage in central nervous system due to inflammation?

1 reference

12 December 2020

Phase-dependent roles of reactive microglia and astrocytes in nervous system injury as delineated by imaging of peripheral benzodiazepine receptor.

1 reference

12 December 2020

Synthesis and in vitro binding of N,N-dialkyl-2-phenylindol-3-yl-glyoxylamides for the peripheral benzodiazepine binding sites

1 reference

12 December 2020

Synthesis and in vivo evaluation of [18F]-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide as a PET imaging probe for COX-2 expression.

1 reference

12 December 2020

Transgenic rat model of Huntington's disease

1 reference

12 December 2020

Drug distribution in man: a positron emission tomography study after oral administration of the labelled neuroprotective drug vinpocetine

1 reference

12 December 2020

Chronic quinolinic acid lesions in rats closely resemble Huntington's disease

1 reference

12 December 2020

DPA-714, a new translocator protein-specific ligand: synthesis, radiofluorination, and pharmacologic characterization

1 reference

12 December 2020

Expression of CD200 by macrophage-like cells in ischemic core of rat brain after transient middle cerebral artery occlusion.

1 reference

12 December 2020

Analysis of inflammation

1 reference

12 December 2020

Development of a new radioligand, N-(5-fluoro-2-phenoxyphenyl)-N-(2-[18F]fluoroethyl-5-methoxybenzyl)acetamide, for pet imaging of peripheral benzodiazepine receptor in primate brain

1 reference

12 December 2020

Evaluation of reference tissue models for the analysis of [11C](R)-PK11195 studies.

1 reference

12 December 2020

The radiosynthesis of [18F]PK 14105 as an alternative radioligand for peripheral type benzodiazepine binding sites

1 reference

12 December 2020

Labelling of "Peripheral-Type" Benzodiazepine Binding Sites in the Rat Brain By Using [3H]PK 11195, an Isoquinoline Carboxamide Derivative: Kinetic Studies and Autoradiographic Localization

1 reference

12 December 2020

Kinetic evaluation in nonhuman primates of two new PET ligands for peripheral benzodiazepine receptors in brain.

1 reference

12 December 2020

SSR180575 (7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide), a peripheral benzodiazepine receptor ligand, promotes neuronal survival and repair

1 reference

12 December 2020

In vivo imaging of brain lesions with [(11)C]CLINME, a new PET radioligand of peripheral benzodiazepine receptors.

1 reference

12 December 2020

Blood flow dependence of the intratumoral distribution of peripheral benzodiazepine receptor binding in intact mouse fibrosarcoma

1 reference

12 December 2020

Brain and whole-body imaging in nonhuman primates of [11C]PBR28, a promising PET radioligand for peripheral benzodiazepine receptors

1 reference

12 December 2020

Evaluation of three quinoline-carboxamide derivatives as potential radioligands for the in vivo pet imaging of neurodegeneration.

1 reference

12 December 2020

Effects of neuroinflammation on glia-glia gap junctional intercellular communication: a perspective

1 reference

12 December 2020

Novel peripheral benzodiazepine receptor ligand [11C]DAA1106 for PET: an imaging tool for glial cells in the brain

1 reference

12 December 2020

In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease

1 reference

12 December 2020

Microglial activation correlates with severity in Huntington disease: a clinical and PET study.

1 reference

12 December 2020

The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity

1 reference

12 December 2020

Translocator protein 18 kDa (TSPO): molecular sensor of brain injury and repair

1 reference

12 December 2020

Radiosynthesis and in vivo evaluation of N-[11C]methylated imidazopyridineacetamides as PET tracers for peripheral benzodiazepine receptors.

1 reference

12 December 2020

Brain kinetics and specific binding of [11C]PK 11195 to omega 3 sites in baboons: positron emission tomography study.

1 reference

12 December 2020

10.1007/S00259-008-0908-9

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828015%20AND%20SRC:MED&resulttype=core&format=json

release_23js63dyobe4lo3s3ghx3354pm

15 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/23js63dyobe4lo3s3ghx3354pm

24 November 2022

mapped directly with Wikidata item

1 reference