(Q37312601)

English

Study protocol for a multicentre randomised controlled trial: Safety, Tolerability, efficacy and quality of life Of a human recombinant alkaline Phosphatase in patients with sepsis-associated Acute Kidney Injury (STOP-AKI).

scientific article published on 27 September 2016

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scholarly article

1 reference

Europe PubMed Central

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24 March 2020

Study protocol for a multicentre randomised controlled trial: Safety, Tolerability, efficacy and quality of life Of a human recombinant alkaline Phosphatase in patients with sepsis-associated Acute Kidney Injury (STOP-AKI) (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27678541%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

multicenter clinical trial

0 references

0 references

quality of life

1 reference

based on heuristic

inferred from title

acute kidney injury

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Patrick T Murray

3

1 reference

Europe PubMed Central

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24 March 2020

6

object named as

John A Kellum

1 reference

Europe PubMed Central

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24 March 2020

Michael Joannidis

5

object named as

Michael Joannidis

1 reference

Europe PubMed Central

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24 March 2020

author name string

Esther Peters

1

1 reference

Europe PubMed Central

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24 March 2020

Ravindra L Mehta

2

1 reference

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24 March 2020

Jürgen Hummel

4

1 reference

Europe PubMed Central

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24 March 2020

Jacques Arend

7

1 reference

Europe PubMed Central

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24 March 2020

Peter Pickkers

8

1 reference

Europe PubMed Central

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24 March 2020

publication date

27 September 2016

1 reference

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24 March 2020

1 reference

Europe PubMed Central

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24 March 2020

6

1 reference

Europe PubMed Central

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24 March 2020

9

1 reference

Europe PubMed Central

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24 March 2020

e012371

1 reference

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24 March 2020

Pharmacokinetic Modeling and Dose Selection in a Randomized, Double-Blind, Placebo-Controlled Trial of a Human Recombinant Alkaline Phosphatase in Healthy Volunteers

1 reference

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6 September 2017

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

1 reference

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6 September 2017

Alkaline phosphatase protects against renal inflammation through dephosphorylation of lipopolysaccharide and adenosine triphosphate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5051490

6 September 2017

Catalytic signature of a heat-stable, chimeric human alkaline phosphatase with therapeutic potential.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5051490

6 September 2017

Alkaline phosphatase: a possible treatment for sepsis-associated acute kidney injury in critically ill patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5051490

6 September 2017

Acute kidney injury: an increasing global concern

1 reference

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6 September 2017

Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012

1 reference

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6 September 2017

SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials

1 reference

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6 September 2017

Four hour creatinine clearance is better than plasma creatinine for monitoring renal function in critically ill patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5051490

6 September 2017

Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: a prospective randomized double-blind placebo-controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5051490

6 September 2017

Lipopolysaccharide directly alters renal tubule transport through distinct TLR4-dependent pathways in basolateral and apical membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5051490

6 September 2017

Intensity of renal support in critically ill patients with acute kidney injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5051490

6 September 2017

Alkaline Phosphatases : Structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5051490

6 September 2017

The epidemiology of sepsis in the United States from 1979 through 2000

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5051490

6 September 2017

The immunopathogenesis of sepsis

1 reference

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6 September 2017

Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine

1 reference

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6 September 2017

Epidemiology of acute kidney injury in the intensive care unit

1 reference

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14 September 2017

Removal of phosphate from lipid A as a strategy to detoxify lipopolysaccharide

1 reference

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14 September 2017

Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study

1 reference

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26 June 2018

Alkaline phosphatase treatment improves renal function in severe sepsis or septic shock patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5051490

2 September 2018

Clinical pharmacology of exogenously administered alkaline phosphatase

1 reference

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2 September 2018

Ecto 5'-nucleotidase and nonspecific alkaline phosphatase. Two AMP-hydrolyzing ectoenzymes with distinct roles in human airways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5051490

2 September 2018

Alkaline phosphatases reduce toxicity of lipopolysaccharides in vivo and in vitro through dephosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5051490

2 September 2018

Evaluation of experiments with adaptive interim analyses.

1 reference

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2 September 2018

Low-dose dopamine in patients with early renal dysfunction: a placebo-controlled randomised trial. Australian and New Zealand Intensive Care Society (ANZICS) Clinical Trials Group

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sepsis-related acute kidney injury: a protective effect of drotrecogin alpha (activated) treatment?

1 reference

https://pubmed.ncbi.nlm.nih.gov/27678541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of the intensity of continuous renal replacement therapy in patients with sepsis and acute kidney injury: a single-center randomized clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/27678541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minimum urine collection periods for accurate determination of creatinine clearance in critically ill patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/27678541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute kidney injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/27678541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1136/BMJOPEN-2016-012371

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27678541%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27678541%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27678541%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

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