(Q37330436)

English

Aberrant Splicing Promotes Proteasomal Degradation of L-type CaV1.2 Calcium Channels by Competitive Binding for CaVβ Subunits in Cardiac Hypertrophy

scientific article published on 12 October 2016

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Aberrant Splicing Promotes Proteasomal Degradation of L-type CaV1.2 Calcium Channels by Competitive Binding for CaVβ Subunits in Cardiac Hypertrophy (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

object named as

Jiong-Wei Wang

2

0 references

Dominique de Kleijn

5

object named as

Dominique P V de Kleijn

0 references

author name string

Zhenyu Hu

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Dejie Yu

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Jia Lin Soon

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Dominique P V de Kleijn

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Roger Foo

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Ping Liao

7

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Henry M Colecraft

8

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Tuck Wah Soong

9

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

language of work or name

0 references

publication date

12 October 2016

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Scientific Reports

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

35247

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

copyright license

Creative Commons Attribution 4.0 International

12 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5059693/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Direct Evidence for Microdomain-Specific Localization and Remodeling of Functional L-Type Calcium Channels in Rat and Human Atrial Myocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Alternative splicing generates a novel truncated Cav1.2 channel in neonatal rat heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Calcium channel blockers and outcomes in older patients with heart failure and preserved ejection fraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

L-type CaV1.2 calcium channels: from in vitro findings to in vivo function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

L-type Ca2+ channel function during Timothy syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Calcium channel auxiliary α2δ and β subunits: trafficking and one step beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Voltage-gated calcium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Ca(V)1.2 channel N-terminal splice variants modulate functional surface expression in resistance size artery smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Alternative splicing of Cav1.2 channel exons in smooth muscle cells of resistance-size arteries generates currents with unique electrophysiological properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Molecular alteration of Ca(v)1.2 calcium channel in chronic myocardial infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Alternative splicing of voltage-gated calcium channels: from molecular biology to disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Dilated cardiomyopathy with increased SR Ca2+ loading preceded by a hypercontractile state and diastolic failure in the alpha(1C)TG mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Atherosclerosis-related molecular alteration of the human CaV1.2 calcium channel alpha1C subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Transcript scanning reveals novel and extensive splice variations in human l-type voltage-gated calcium channel, Cav1.2 alpha1 subunit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Functional embryonic cardiomyocytes after disruption of the L-type alpha1C (Cav1.2) calcium channel gene in the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Efficacy and safety of calcium channel blockers in heart failure: focus on recent trials with second-generation dihydropyridines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

A beta 4 isoform-specific interaction site in the carboxyl-terminal region of the voltage-dependent Ca2+ channel alpha 1A subunit

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

https://api.crossref.org/works/10.1038%2FSREP35247

21 January 2018

Direct interaction of Gβγ with a C-terminal Gβγ-binding domain of the Ca 2+ channel α 1 subunit is responsible for channel inhibition by G protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

6 September 2017

Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

14 September 2017

Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

14 September 2017

A destructive interaction mechanism accounts for dominant-negative effects of misfolded mutants of voltage-gated calcium channels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

14 September 2017

Cardiac L-type calcium channel beta-subunits expressed in human heart have differential effects on single channel characteristics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

14 September 2017

Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

1 July 2018

Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

1 July 2018

N terminus is key to the dominant negative suppression of Ca(V)2 calcium channels: implications for episodic ataxia type 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

1 July 2018

L-type Ca2+ channel density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

1 July 2018

L-type calcium currents of human myocytes from ventricle of non-failing and failing hearts and from atrium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

1 July 2018

Effect of amlodipine on the survival of patients with severe chronic heart failure due to a nonischemic cardiomyopathy: results of the PRAISE-2 study (prospective randomized amlodipine survival evaluation 2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

2 September 2018

A caveolae-targeted L-type Ca²+ channel antagonist inhibits hypertrophic signaling without reducing cardiac contractility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

2 September 2018

Mechanism of auxiliary β-subunit-mediated membrane targeting of L-type (Ca(V)1.2) channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

2 September 2018

Decrease in the density of t-tubular L-type Ca2+ channel currents in failing ventricular myocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

2 September 2018

Reduced cardiac L-type Ca2+ current in Ca(V)beta2-/- embryos impairs cardiac development and contraction with secondary defects in vascular maturation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

2 September 2018

Reduced calcium current density in single myocytes isolated from hypertrophied failing guinea pig hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059693

2 September 2018

p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload

1 reference

https://api.crossref.org/works/10.1038%2FSREP35247

21 January 2018

Splice variant specific modulation of CaV1.2 calcium channel by galectin-1 regulates arterial constriction

1 reference

https://pubmed.ncbi.nlm.nih.gov/27731386

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-type Ca2+ channel alpha 1c subunit isoform switching in failing human ventricular myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/27731386

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Cavβ subunit prevents RFP2-mediated ubiquitination and proteasomal degradation of L-type channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/27731386

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reemergence of the fetal pattern of L-type calcium channel gene expression in non infarcted myocardium during left ventricular remodeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/27731386

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

β(2)-Adrenergic and M(2)-muscarinic receptors decrease basal t-tubular L-type Ca2+ channel activity and suppress ventricular contractility in heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/27731386

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trafficking of L-type calcium channels mediated by the postsynaptic scaffolding protein AKAP79

1 reference

https://pubmed.ncbi.nlm.nih.gov/27731386

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SREP35247

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q37330436&oldid=2200183095"