(Q37330722)

19 August 2017

1 reference

title

Quantitative modeling perspectives on the ErbB system of cell regulatory processes (English)

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19 August 2017

Douglas A. Lauffenburger

series ordinal

2

object named as

Douglas A Lauffenburger

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19 August 2017

Matthew J Lazzara

1

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PubMed ID

19022246

19 August 2017

language of work or name

English

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publication date

5 November 2008

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Experimental Cell Research

19 August 2017

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19 August 2017

315

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19 August 2017

717-725

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19 August 2017

4

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Computational modeling of the EGF-receptor system: a paradigm for systems biology

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

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Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways

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Decreased internalisation of erbB1 mutants in lung cancer is linked with a mechanism conferring sensitivity to gefitinib

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Cell surface receptors for signal transduction and ligand transport: a design principles study.

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EGF and amphiregulin differentially regulate Cbl recruitment to endosomes and EGF receptor fate

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Ligand accumulation in autocrine cell cultures

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Argos inhibits epidermal growth factor receptor signalling by ligand sequestration

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Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor

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Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

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Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses

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Parsing ERK activation reveals quantitatively equivalent contributions from epidermal growth factor receptor and HER2 in human mammary epithelial cells

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A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling

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Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

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Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks

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Effects of HER2 overexpression on cell signaling networks governing proliferation and migration

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Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules

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A quantitative protein interaction network for the ErbB receptors using protein microarrays

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System-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties

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A module of negative feedback regulators defines growth factor signaling

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Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling

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Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops

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Reduction of mathematical models of signal transduction networks: simulation-based approach applied to EGF receptor signalling.

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A multiscale computational approach to dissect early events in the Erb family receptor mediated activation, differential signaling, and relevance to oncogenic transformations

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Building with a scaffold: emerging strategies for high- to low-level cellular modeling

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A biological approach to computational models of proteomic networks

7 January 2021

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Quantitative transcriptional control of ErbB receptor signaling undergoes graded to biphasic response for cell differentiation.

7 January 2021

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Modeling HER2 effects on cell behavior from mass spectrometry phosphotyrosine data

7 January 2021

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Multipathway model enables prediction of kinase inhibitor cross-talk effects on migration of Her2-overexpressing mammary epithelial cells

7 January 2021

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A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis.

7 January 2021

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Common effector processing mediates cell-specific responses to stimuli

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Quantitative network signal combinations downstream of TCR activation can predict IL-2 production response

7 January 2021

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Modeling of signal-response cascades using decision tree analysis.

7 January 2021

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Decision tree modeling predicts effects of inhibiting contractility signaling on cell motility

7 January 2021

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Drosophila eggshell is patterned by sequential action of feedforward and feedback loops.

7 January 2021

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The effects of EGF-receptor density on multiscale tumor growth patterns.

7 January 2021

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Simulating non-small cell lung cancer with a multiscale agent-based model

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10.1016/J.YEXCR.2008.10.033

7 January 2021

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

19022246