(Q37331829)

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Fibroblast growth factor receptor 1 promotes proliferation and survival via activation of the mitogen-activated protein kinase pathway in bladder cancer

scientific article published on 19 May 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Fibroblast growth factor receptor 1 promotes proliferation and survival via activation of the mitogen-activated protein kinase pathway in bladder cancer (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Margaret A Knowles

4

object named as

Margaret A Knowles

0 references

object named as

Fiona R Lamont

2

0 references

Darren C. Tomlinson

object named as

Darren C Tomlinson

1

0 references

author name string

Steve D Shnyder

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

language of work or name

0 references

publication date

19 May 2009

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Cancer Research

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

69

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

4613-4620

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Cancer statistics, 2008

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

6 September 2017

FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

6 September 2017

Expression of hTERT immortalises normal human urothelial cells without inactivation of the p16/Rb pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

6 September 2017

Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

6 September 2017

Molecular subtypes of bladder cancer: Jekyll and Hyde or chalk and cheese?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

6 September 2017

Urothelial tumorigenesis: a tale of divergent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

6 September 2017

Cellular signaling by fibroblast growth factor receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

6 September 2017

Cancer. Addiction to oncogenes--the Achilles heal of cancer

1 reference

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6 September 2017

Tyrosine kinase fusion genes in chronic myeloproliferative diseases.

1 reference

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6 September 2017

Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland

1 reference

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6 September 2017

Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

6 September 2017

High-throughput tissue microarray analysis of 3p25 (RAF1) and 8p12 (FGFR1) copy number alterations in urinary bladder cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

6 September 2017

Fibroblast growth factors, their receptors and signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

6 September 2017

Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus

1 reference

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6 September 2017

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

6 September 2017

Shc and a novel 89-kDa component couple to the Grb2-Sos complex in fibroblast growth factor-2-stimulated cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

6 September 2017

Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

14 September 2017

Auristatin PYE, a novel synthetic derivative of dolastatin 10, is highly effective in human colon tumour models.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

14 September 2017

Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: role of fibroblast growth factor receptor-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

14 September 2017

FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

14 September 2017

The inhibitory anti-FGFR3 antibody, PRO-001, is cytotoxic to t(4;14) multiple myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

14 September 2017

Alternative splicing of fibroblast growth factor receptor 3 produces a secreted isoform that inhibits fibroblast growth factor-induced proliferation and is repressed in urothelial carcinoma cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

14 September 2017

FGFR3 as a therapeutic target of the small molecule inhibitor PKC412 in hematopoietic malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

14 September 2017

The economic consequences of prostate and bladder cancer in the UK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

14 September 2017

CHIR-258, a novel, multitargeted tyrosine kinase inhibitor for the potential treatment of t(4;14) multiple myeloma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

14 September 2017

Targeting FGFR3 in multiple myeloma: inhibition of t(4;14)-positive cells by SU5402 and PD173074.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

14 September 2017

Messenger ribonucleic acids for fibroblast growth factors and their receptor in bladder and renal cell carcinoma cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

28 September 2017

Reduced activation of RAF-1 and MAP kinase by a fibroblast growth factor receptor mutant deficient in stimulation of phosphatidylinositol hydrolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

28 September 2017

Oncogenic properties of the mutated forms of fibroblast growth factor receptor 3b.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

26 June 2018

Dynamic transcriptional regulatory complexes, including E2F4, p107, p130, and Sp1, control fibroblast growth factor receptor 1 gene expression during myogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

26 June 2018

Normal human urothelial cells in vitro: proliferation and induction of stratification.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

26 June 2018

Increased levels of fibroblast growth factor-like activity in urine from patients with bladder or kidney cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

26 June 2018

Immunohistochemical detection of acidic fibroblast growth factor in bladder transitional cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

26 June 2018

Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

2 September 2018

Sp1 is required for transcriptional activation of the fibroblast growth factor receptor 1 gene in neonatal cardiomyocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

2 September 2018

FGFR3 and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

2 September 2018

Array-based comparative genomic hybridization for genome-wide screening of DNA copy number in bladder tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

2 September 2018

EGF receptor activation by heterologous mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

2 September 2018

Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737316

2 September 2018

PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19458078

12 December 2020

based on heuristic

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Expression of FGF and FGF receptor genes in human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19458078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urinary basic fibroblast growth factor in patients with bladder cancer and benign prostatic hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19458078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased expression of keratinocyte growth factor receptor in a subset of human transitional cell bladder carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/19458078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction by fibroblast growth factor receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19458078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in expression of basic fibroblast growth factor (FGF) 2 and its receptor FGFR-1 in human prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19458078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fibroblast growth factor receptor 3 (FGFR3) mutation is a strong indicator of superficial bladder cancer with low recurrence rate

1 reference

https://pubmed.ncbi.nlm.nih.gov/19458078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tumor-suppressive functions of the human INK4A locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19458078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19458078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19458078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-08-2816

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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