(Q38314203)

2 September 2017

Expression of hTERT immortalises normal human urothelial cells without inactivation of the p16/Rb pathway (English)

1 reference

2 September 2017

0 references

Chapman EJ

1

1 reference

2 September 2017

Hurst CD

2

1 reference

2 September 2017

Pitt E

3

1 reference

2 September 2017

Chambers P

4

1 reference

2 September 2017

Aveyard JS

5

1 reference

2 September 2017

Knowles MA

6

1 reference

2 September 2017

language of work or name

English

0 references

publication date

17 April 2006

1 reference

2 September 2017

1 reference

2 September 2017

25

1 reference

2 September 2017

5037-5045

1 reference

2 September 2017

36

1 reference

describes a project that uses

2 September 2017

0 references

0 references

0 references

https://scigraph.springernature.com/pub.10.1038/sj.onc.1209513

0 references

cites work

Id1 regulation of cellular senescence through transcriptional repression of p16/Ink4a.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Measurement of relative copy number of CDKN2A/ARF and CDKN2B in bladder cancer by real-time quantitative PCR and multiplex ligation-dependent probe amplification

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Telomerase activity: a biomarker of cell proliferation, not malignant transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Direct evidence from siRNA-directed "knock down" that p16(INK4a) is required for human fibroblast senescence and for limiting ras-induced epithelial cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Control of replicative life span in human cells: barriers to clonal expansion intermediate between M1 senescence and M2 crisis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Comprehensive analysis of CDKN2A status in microdissected urothelial cell carcinoma reveals potential haploinsufficiency, a high frequency of homozygous co-deletion and associations with clinical phenotype.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Immortalisation and transformation revisited

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Adriamycin-induced senescence in breast tumor cells involves functional p53 and telomere dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Genetic and epigenetic changes in human epithelial cells immortalized by telomerase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

High-resolution analysis of genomic copy number alterations in bladder cancer by microarray-based comparative genomic hybridization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

dChipSNP: significance curve and clustering of SNP-array-based loss-of-heterozygosity data

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Tumor suppression by Ink4a-Arf: progress and puzzles

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

What we could do now: molecular pathology of bladder cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Senescing oral dysplasias are not immortalized by ectopic expression of hTERT alone without other molecular changes, such as loss of INK4A and/or retinoic acid receptor-β: but p53 mutations are not necessarily required

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Replicative senescence in human uroepithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

hTERT antagonizes p53-induced apoptosis independently of telomerase activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

20q gain associates with immortalization: 20q13.2 amplification correlates with genome instability in human papillomavirus 16 E7 transformed human uroepithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Telomerase modulates expression of growth-controlling genes and enhances cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Telomerase contributes to tumorigenesis by a telomere length-independent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Cell-surface receptor for ecotropic murine retroviruses is a basic amino-acid transporter.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Immortalization of distinct human mammary epithelial cell types by human papilloma virus 16 E6 or E7.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Telomerase Alone Extends the Replicative Life Span of Human Skeletal Muscle Cells Without Compromising Genomic Stability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Human endothelial cell life extension by telomerase expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Overcoming cellular senescence in human cancer pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209513

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209513

1 reference

Dimensions Publication ID

2 September 2017

0 references

1 reference