(Q37340398)

19 August 2017

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title

New targets and treatments in multiple myeloma: Src family kinases as central regulators of disease progression (English)

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19 August 2017

1

Morie A Gertz

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19 August 2017

language of work or name

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1 December 2008

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19 August 2017

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19 August 2017

volume

49

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19 August 2017

issue

12

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19 August 2017

page(s)

2240-2245

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Molecular mechanisms of novel therapeutic approaches for multiple myeloma

19 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

Multiple myeloma: an old disease with new hope for the future

21 January 2018

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Molecular aspects of multiple myeloma.

21 January 2018

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Mechanisms of bone metastasis

21 January 2018

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Thalidomide and dexamethasone: therapy for multiple myeloma.

21 January 2018

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Multiple myeloma: charging toward a bright future.

21 January 2018

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Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: a clinical trial coordinated by the Eastern Cooperative Oncology Group

21 January 2018

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21 January 2018

New drugs for myeloma

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Mitogenic signals initiated via interleukin-6 receptor complexes in cooperation with other transmembrane molecules in myelomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

Selective expression of a protein-tyrosine kinase, p56lyn, in hematopoietic cells and association with production of human T-cell lymphotropic virus type I

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

Interleukin-6-induced proliferation of human myeloma cells associated with CD45 molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

The protein tyrosine phosphatase CD45 is required for interleukin 6 signaling in U266 myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

Interleukin-7 Induces MUC1

21 January 2018

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https://api.crossref.org/works/10.1080%2F10428190802475311

Bortezomib (Velcadetrade mark) in the Treatment of Multiple Myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

Bortezomib or high-dose dexamethasone for relapsed multiple myeloma

21 January 2018

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https://api.crossref.org/works/10.1080%2F10428190802475311

High response rate and improved graft-versus-host disease following bortezomib as salvage therapy after reduced intensity conditioning allogeneic stem cell transplantation for multiple myeloma

21 January 2018

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Bortezomib plus melphalan and prednisone in elderly untreated patients with multiple myeloma: updated time-to-events results and prognostic factors for time to progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma

21 January 2018

1 reference

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Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

Small-molecule inhibition of proteasome and silencing by vascular endothelial cell growth factor-specific siRNA induce additive antitumor activity in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

Caveolin-1 is required for vascular endothelial growth factor-triggered multiple myeloma cell migration and is targeted by bortezomib

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays.

21 January 2018

1 reference

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Curcumin (Diferuloylmethane) Inhibits Constitutive and IL-6-Inducible STAT3 Phosphorylation in Human Multiple Myeloma Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

Identification and validation of phospho-SRC, a novel and potential pharmacodynamic biomarker for dasatinib (SPRYCEL), a multi-targeted kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

Expression of c-Kit isoforms in multiple myeloma: differences in signaling and drug sensitivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

Potent inhibition of platelet-derived growth factor-induced responses in vascular smooth muscle cells by BMS-354825 (dasatinib).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

Validation of PDGFRbeta and c-Src tyrosine kinases as tumor/vessel targets in patients with multiple myeloma: preclinical efficacy of the novel, orally available inhibitor dasatinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

Single agent dexamethasone for pre-stem cell transplant induction therapy for multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190802475311

10.1080/10428190802475311

21 January 2018

Identifiers

DOI

1 reference

19 August 2017

1 reference