(Q37341652)

19 August 2017

1 reference

title

Intracellular and extracellular serpins modulate lung disease (English)

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19 August 2017

D J Askew

1

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19 August 2017

G A Silverman

series ordinal

2

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19 August 2017

publication date

1 December 2008

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19 August 2017

published in

Journal of Perinatology

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19 August 2017

volume

28 Suppl 3

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19 August 2017

page(s)

S127-35

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https://scigraph.springernature.com/pub.10.1038/jp.2008.150

19 August 2017

exact match

0 references

cites work

Serpin structure, mechanism, and function

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Structure of a serpin-protease complex shows inhibition by deformation

21 January 2018

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https://api.crossref.org/works/10.1038%2FJP.2008.150

The mechanism of Z alpha 1-antitrypsin accumulation in the liver

21 January 2018

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Alpha1-antitrypsin deficiency--a model for conformational diseases

21 January 2018

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Human plasma proteinase inhibitors

21 January 2018

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https://api.crossref.org/works/10.1038%2FJP.2008.150

alpha 1-Antitrypsin: molecular pathology, leukocytes, and tissue damage

21 January 2018

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State of the art. Mechanistic heterogeneity in chronic obstructive pulmonary disease: insights from transgenic mice

21 January 2018

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Lung polymers in Z alpha1-antitrypsin deficiency-related emphysema

21 January 2018

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https://api.crossref.org/works/10.1038%2FJP.2008.150

Polymers of Z alpha1-antitrypsin co-localize with neutrophils in emphysematous alveoli and are chemotactic in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Polymers of alpha(1)-antitrypsin are chemotactic for human neutrophils: a new paradigm for the pathogenesis of emphysema

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Therapeutic level of functional human alpha 1 antitrypsin (hAAT) secreted from murine muscle transduced by adeno-associated virus (rAAV1) vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Preclinical characterization of a recombinant adeno-associated virus type 1-pseudotyped vector demonstrates dose-dependent injection site inflammation and dissemination of vector genomes to distant sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Potential role of inhibitors of neutrophil elastase in treating diseases of the airway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Grp78, Grp94, and Grp170 interact with alpha1-antitrypsin mutants that are retained in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Chemical chaperones mediate increased secretion of mutant alpha 1-antitrypsin (alpha 1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in alpha 1-AT deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Lack of effect of oral 4-phenylbutyrate on serum alpha-1-antitrypsin in patients with alpha-1-antitrypsin deficiency: a preliminary study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Exacerbations in cystic fibrosis. 1: Epidemiology and pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Safety and efficacy of recombinant alpha(1)-antitrypsin therapy in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Prevention of bronchopulmonary dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Pathogenesis of bronchopulmonary dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Elastase and alpha 1-proteinase inhibitor activity in tracheal aspirates during respiratory distress syndrome. Role of inflammation in the pathogenesis of bronchopulmonary dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Inflammation and bronchopulmonary dysplasia

21 January 2018

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https://api.crossref.org/works/10.1038%2FJP.2008.150

Tracheobronchial aspirate fluid neutrophil lipocalin, elastase- and neutrophil protease-4-alpha1-antitrypsin complexes, protease inhibitors and free proteolytic activity in respiratory distress syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Apoptosis of airway epithelial cells in response to meconium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Human meconium has high phospholipase A2 activity and induces cellular injury and apoptosis in piglet lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Meconium aspiration induces a concentration-dependent pulmonary hypertensive response in newborn piglets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Characterization of serine/cysteine protease inhibitor alpha1-antitripsin from meconium-instilled rabbit lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Clinical practice. Acute pulmonary edema

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Disturbed alveolar fibrin turnover during pneumonia is restricted to the site of infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Procoagulant and fibrinolytic activity in ventilator-associated pneumonia: impact of inadequate antimicrobial therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Cellular origin of pro-coagulant and (anti)-fibrinolytic factors in bleomycin-injured lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Plasminogen activator inhibitor type-1 deficiency does not influence the outcome of murine pneumococcal pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Antithrombin: in control of coagulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Effects of various doses of antithrombin III on endotoxin-induced endothelial cell injury and coagulation abnormalities in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Antithrombin III prevents early pulmonary dysfunction after lung transplantation in the dog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of antithrombin III, protein C, and protein S deficiencies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Antithrombin III (ATIII) replacement therapy in patients with sepsis and/or postsurgical complications: a controlled double-blind, randomized, multicenter study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Control of the coagulation system by serpins. Getting by with a little help from glycosaminoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Disruption of the protein C inhibitor gene results in impaired spermatogenesis and male infertility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Characterization of a novel human protein C inhibitor (PCI) gene transgenic mouse useful for studying the role of PCI in physiological and pathological conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Is protein C inhibitor antithrombotic and protective in pulmonary hypertension?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Thrombin-activatable fibrinolysis inhibitor and protein C inhibitor in interstitial lung disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

A fast-acting elastase inhibitor in human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Inhibition of apoptosis in human tumour cells by the tumour-associated serpin, SCC antigen-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Squamous cell carcinoma antigen suppresses radiation-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

SERPINB12 is a novel member of the human ov-serpin family that is widely expressed and inhibits trypsin-like serine proteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

The serpin MNEI inhibits elastase-like and chymotrypsin-like serine proteases through efficient reactions at two active sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Linkage of neutrophil serine proteases and decreased surfactant protein-A (SP-A) levels in inflammatory lung disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Human monocyte/neutrophil elastase inhibitor (MNEI) is regulated by PU.1/Spi-1, Sp1, and NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

The undecided serpin. The ins and outs of plasminogen activator inhibitor type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

A novel matrix attachment region DNA binding motif identified using a random phage peptide library

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis--CREB and NF-kappaB as key regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Co-expression of the squamous cell carcinoma antigens 1 and 2 in normal adult human tissues and squamous cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Cross-class inhibition of the cysteine proteinases cathepsins K, L, and S by the serpin squamous cell carcinoma antigen 1: a kinetic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Squamous cell carcinoma antigen 2 is a novel serpin that inhibits the chymotrypsin-like proteinases cathepsin G and mast cell chymase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Analysis of novel disease-related genes in bronchial asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Caspase-independent cell deaths

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

21 January 2018

Lysosomes in cell death

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Imbalance between cysteine proteases and inhibitors in a baboon model of bronchopulmonary dysplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

A role for the granzyme B inhibitor serine protease inhibitor 6 in CD8+ memory cell homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Expression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: differential modulation by T helper type 1 and type 2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Serine protease inhibitor 6 protects cytotoxic T cells from self-inflicted injury by ensuring the integrity of cytotoxic granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

The granzyme B inhibitor, protease inhibitor 9, is mainly expressed by dendritic cells and at immune-privileged sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

Developmental expression of plasminogen activator inhibitor type 1 by human alveolar macrophages. Possible role in lung injury

21 January 2018

1 reference

12 December 2020

High-dose antithrombin III treatment of severely injured patients: results of a prospective study

1 reference

12 December 2020

Alveolar Fibrin Formation Caused by Enhanced Procoagulant and Depressed Fibrinolytic Capacities in Severe Pneumonia

1 reference

12 December 2020

alpha1-Proteinase inhibitor therapy for the prevention of chronic lung disease of prematurity: a randomized, controlled trial

1 reference

12 December 2020

Antithrombin III in patients with severe sepsis. A randomized, placebo-controlled, double-blind multicenter trial plus a meta-analysis on all randomized, placebo-controlled, double-blind trials with antithrombin III in severe sepsis

1 reference

12 December 2020

Increased procoagulant and antifibrinolytic activities in the lungs with idiopathic pulmonary fibrosis

1 reference

12 December 2020

Aerosolized prolastin suppresses bacterial proliferation in a model of chronic Pseudomonas aeruginosa lung infection

1 reference

12 December 2020

Compartment- and cell-specific expression of coagulation and fibrinolysis factors in the murine lung undergoing inhalational versus intravenous endotoxin application

1 reference

12 December 2020

Glycosaminoglycans regulate the enzyme specificity of protein C inhibitor

1 reference

12 December 2020

Heparin binding to protein C inhibitor

1 reference

12 December 2020

Proteinase-antiproteinase balance in tracheal aspirates from neonates

1 reference

12 December 2020

A registry of patients with severe deficiency of alpha 1-antitrypsin. Design and methods. The Alpha 1-Antitrypsin Deficiency Registry Study Group

1 reference

12 December 2020

Heterozygous MZ alpha 1-antitrypsin deficiency in adults with chronic active hepatitis and cryptogenic cirrhosis

1 reference

12 December 2020

Sex steroid hormones in circulatory shock, sepsis syndrome, and septic shock

1 reference

12 December 2020

Recombinant human Monocyte/Neutrophil elastase inhibitor protects rat lungs against injury from cystic fibrosis airway secretions

1 reference

12 December 2020

Neonatal chronic lung disease in extremely immature baboons

1 reference

12 December 2020

Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency

1 reference

12 December 2020

Alpha-1 proteinase inhibitor (a1PI) for preventing chronic lung disease in preterm infants.

1 reference

12 December 2020

Cell death and lung cell histology in meconium aspirated newborn rabbit lung

1 reference

12 December 2020

Secretory leukocyte protease inhibitor and lung inflammation in developing bronchopulmonary dysplasia

1 reference

12 December 2020

High concentrations of plasminogen activator inhibitor-1 in lungs of preterm infants with respiratory distress syndrome

1 reference

12 December 2020

Protective role of protein C inhibitor in monocrotaline-induced pulmonary hypertension

1 reference

12 December 2020

The intracellular serpin proteinase inhibitor 6 is expressed in monocytes and granulocytes and is a potent inhibitor of the azurophilic granule protease, cathepsin G.

1 reference

12 December 2020

Turnover of *I-protein C inhibitor and *I-alpha 1-antitrypsin and their complexes with activated protein C

1 reference

12 December 2020

Atopy, asthma, and emphysema in patients with severe alpha-1-antitrypysin deficiency

1 reference

12 December 2020

Plasminogen activator inhibitor-1 potentiates LPS-induced neutrophil activation through a JNK-mediated pathway.

1 reference

12 December 2020

Aerosol α1 -antitrypsin treatment for cystic fibrosis

1 reference

12 December 2020

Protein C inhibitor regulates the thrombin-thrombomodulin complex in the up- and down regulation of TAFI activation.

1 reference

12 December 2020

Revisiting alpha1-antitrypsin therapy in cystic fibrosis: can it still offer promise?

1 reference

12 December 2020

alpha1-Antitrypsin inhalation reduces airway inflammation in cystic fibrosis patients

1 reference

12 December 2020

Protection from tumor necrosis factor-mediated cytolysis by overexpression of plasminogen activator inhibitor type-2.

1 reference

12 December 2020

Protein C inhibitor, a serpin with functions in- and outside vascular biology.

1 reference

12 December 2020

SERPINB1 upregulation is associated with in vivo complex formation with neutrophil elastase and cathepsin G in a baboon model of bronchopulmonary dysplasia

1 reference

12 December 2020

Plasminogen activator inhibitor type 2 inhibits tumor necrosis factor alpha-induced apoptosis. Evidence for an alternate biological function

1 reference

12 December 2020

Protein C Inhibitor Is a Potent Inhibitor of the Thrombin-Thrombomodulin Complex

1 reference

12 December 2020

Regulation of Hemostasis by Heparin-Binding Serpins

1 reference

https://api.crossref.org/works/10.1038%2FJP.2008.150

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/JP.2008.150

1 reference

Dimensions Publication ID

19 August 2017

1027335918

0 references

PMC publication ID

7104463

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1 reference