(Q37349831)

19 August 2017

1 reference

title

Autophagy genes and ageing (English)

1 reference

19 August 2017

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T Vellai

1

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19 August 2017

12 September 2008

1 reference

Cell Death & Differentiation

19 August 2017

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19 August 2017

16

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19 August 2017

1

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19 August 2017

94-102

1 reference

https://scigraph.springernature.com/pub.10.1038/cdd.2008.126

19 August 2017

0 references

cites work

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Genetics and the specificity of the aging process

21 January 2018

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Genetic links between diet and lifespan: shared mechanisms from yeast to humans

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Autophagy and aging: the importance of maintaining "clean" cells

21 January 2018

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Autophagy genes unc-51 and bec-1 are required for normal cell size in Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2008.126

Regulation of cell growth by autophagy

21 January 2018

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Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2008.126

Inactivation of the autophagy gene bec-1 triggers apoptotic cell death in C. elegans

21 January 2018

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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

21 January 2018

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Loss of autophagy in the central nervous system causes neurodegeneration in mice

21 January 2018

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The plasticity of aging: insights from long-lived mutants

21 January 2018

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Genetics of aging in Caenorhabditis elegans

21 January 2018

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A C. elegans mutant that lives twice as long as wild type

21 January 2018

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A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

21 January 2018

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Evidence that the gene encoding insulin degrading enzyme influences human lifespan

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2008.126

Insulin signalling and the regulation of glucose and lipid metabolism

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2008.126

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

21 January 2018

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A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2008.126

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2008.126

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

21 January 2018

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Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

21 January 2018

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FoxO transcription factors in the maintenance of cellular homeostasis during aging

21 January 2018

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JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling

21 January 2018

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JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16.

21 January 2018

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The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2008.126

Cross-talk between IGF-I and TGF-beta signaling pathways

21 January 2018

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Genetics: influence of TOR kinase on lifespan in C. elegans

21 January 2018

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The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2008.126

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

21 January 2018

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Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control

21 January 2018

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The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans

21 January 2018

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Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

21 January 2018

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Ribosomal S6 kinase signaling and the control of translation

21 January 2018

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The mRNA 5' cap-binding protein eIF4E and control of cell growth

21 January 2018

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eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans

21 January 2018

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Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans

21 January 2018

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Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans

21 January 2018

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Ageing and the regulation of protein synthesis: a balancing act?

21 January 2018

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C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span

21 January 2018

1 reference

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

21 January 2018

1 reference

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Sirtuin activators mimic caloric restriction and delay ageing in metazoans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Resveratrol improves health and survival of mice on a high-calorie diet

21 January 2018

1 reference

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Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

21 January 2018

1 reference

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Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2008.126

Transcriptional control of the core cell-death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Modulation of mammalian life span by the short isoform of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Mutations that increase the life span of C. elegans inhibit tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Catabolic insufficiency and aging

21 January 2018

1 reference

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Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

ROS, mitochondria and the regulation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Rates of behavior and aging specified by mitochondrial function during development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Mitochondrial superoxide decreases yeast survival in stationary phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

The effects of exogenous antioxidants on lifespan and oxidative stress resistance in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Dietary restriction in C. elegans: from rate-of-living effects to nutrient sensing pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Autophagy as a regulated pathway of cellular degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Autophagy: in sickness and in health

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

The molecular machinery of autophagy: unanswered questions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Molecular machinery of autophagosome formation in yeast, Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Autophagy in the Pathogenesis of Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Eaten alive: autophagy and neuronal cell death after hypoxia-ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Autophagy genes are essential for dauer development and life-span extension in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

SNF4Agamma, the Drosophila AMPK gamma subunit is required for regulation of developmental and stress-induced autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Regulation of autophagy by cytoplasmic p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

E2F1 regulates autophagy and the transcription of autophagy genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Autophagy regulates ageing in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Dual roles of autophagy in the survival of Caenorhabditis elegans during starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Autophagy is required for dietary restriction-mediated life span extension in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

A role for autophagy in the extension of lifespan by dietary restriction in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Neurodegeneration induces upregulation of Beclin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Autophagy and its possible roles in nervous system diseases, damage and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

The roles of intracellular protein-degradation pathways in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Regulation of Caenorhabditis elegans lifespan by a proteasomal E3 ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Autophagy fights disease through cellular self-digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Autophagy in aging and in neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Delayed ageing through damage protection by the Arf/p53 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Cost-free longevity in mice?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

Ambra1 regulates autophagy and development of the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

inferred from DOI database lookup

7 January 2021

based on heuristic

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

inferred from DOI database lookup

7 January 2021

based on heuristic

Sequestration revisited: integrating traditional electron microscopy, de novo assembly and new results

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.126

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/CDD.2008.126

1 reference

19 August 2017

1 reference

PubMed ID

19079287