(Q37352067)

English

Chronic exposure of betaTC-6 cells to supraphysiologic concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator

scientific article published on February 1996

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Chronic exposure of betaTC-6 cells to supraphysiologic concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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author name string

V Poitout

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

L K Olson

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

R P Robertson

3

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Europe PubMed Central

PMC publication ID

19 August 2017

language of work or name

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publication date

1 February 1996

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Europe PubMed Central

PMC publication ID

19 August 2017

Journal of Clinical Investigation

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Europe PubMed Central

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19 August 2017

97

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Europe PubMed Central

PMC publication ID

19 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

1041-1046

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein.

1 reference

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Expression of the trans-active factors that stimulate insulin control element-mediated activity appear to precede insulin gene transcription.

1 reference

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6 September 2017

Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression

1 reference

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Insulin-promoter-factor 1 is required for pancreas development in mice

1 reference

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IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene

1 reference

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6 September 2017

Reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression

1 reference

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Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed

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Sequence of a cDNA Encoding Syrian Hamster Preproinsulin

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Firefly luciferase gene: structure and expression in mammalian cells

1 reference

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Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene

1 reference

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6 September 2017

Type II diabetes, glucose "non-sense," and islet desensitization

1 reference

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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Cooperativity of sequence elements mediates tissue specificity of the rat insulin II gene

1 reference

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Metabolic control of insulin gene expression and biosynthesis

1 reference

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6 September 2017

Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations

1 reference

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6 September 2017

Definition of the carbohydrate response element of the rat S14 gene. Evidence for a common factor required for carbohydrate regulation of hepatic genes

1 reference

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6 September 2017

Differentiating glucose toxicity from glucose desensitization: a new message from the insulin gene

1 reference

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14 September 2017

IPF1, a homeodomain-containing transactivator of the insulin gene

1 reference

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28 September 2017

Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the beta-cell function

1 reference

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28 September 2017

Morphological and functional characterization of beta TC-6 cells--an insulin-secreting cell line derived from transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507151

28 September 2017

The reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to high glucose concentration is associated with the loss of RIPE3b1 and STF-1 transcription factor expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507151

28 September 2017

The defective glucose sensitivity of the B cell in non insulin dependent diabetes. Improvement after twenty hours of normoglycaemia

1 reference

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26 June 2018

Hyperglycaemia as an inducer as well as a consequence of impaired islet cell function and insulin resistance: implications for the management of diabetes.

1 reference

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26 June 2018

Quantitative analysis of pancreatic proinsulin mRNA in genetically diabetic (db/db) mice.

1 reference

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26 June 2018

A tissue-specific nuclear factor binds to multiple sites in the human insulin-gene enhancer

1 reference

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26 June 2018

Insulin secretion and cAMP metabolism in HIT cells. Reciprocal and serial passage-dependent relationships

1 reference

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26 June 2018

Cell-specific and ubiquitous factors are responsible for the enhancer activity of the rat insulin II gene

1 reference

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26 June 2018

Beta-cell function improved by supplementing basal insulin secretion in mild diabetes

1 reference

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26 June 2018

Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

1 reference

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2 September 2018

Identifiers

10.1172/JCI118496

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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